一百二十八、活血散。治是疮疹证不出，或出而迟，或出而倒靥者，皆宜服之。
上用白芍药炒为细末，用温酒调服，或入酒一匙则出快。如欲止痛者，只用温热水调服
之，以意寻之，此乃调荣卫药也。盖张氏《妙选方》云∶疮疹气匀即出，快气行，由荣卫无
阻矣。又芍药主时行寒热、消痈肿，则治疮痘矣。《素问》论脚受血而能行，目受血而能视
，手受血而能握物。《活人书》一证感寒，寸大尺弱，两足拘挛，为下焦血少，不能伸，用
芍药甘草汤三服，遂脚伸不拘挛能行，常用有效，又有老贵人不能拜跪，宣医用六辛汤，乃
是白芍药六两，甘草半两，服十日而能行，此亦活血散，行荣卫也。
一百二十九、人齿散。治疮疹已出而不快，既出而倒靥，患疮疹作寒热而脉反迟者，或
攻皮肤而出迟，或面额赤，脉不洪大者，或服凉药过多，血涩气弱，或出之未快，隐隐在皮
肤间，以酒调服之。钱乙附方，治疮疹倒靥，入麝香酒调服之。尤佳。又云∶疮疹倒靥不出
，加赤小豆七粒，薄荷酒调服之。若黑色者，名曰∶鬼疮子，用 猪血调下二钱，移时再服
之。
上用人齿脱落者，以瓷瓶固济，大火 令通赤，候冷取出为末，用薄荷酒调服之，半钱
。良久脉平，毒瓦斯散，疮如粟米而出，详之，此为发出疮疹之药也。如伤寒表汗之药，故伤
寒发汗，须看荣卫之浅深，疮疹表出，须看蕴热之多少也，恐蕴热少而用药过，为斑烂故也
。其已出而未快者，活血散蒺藜酒、葡萄酒之类可也。既出而倒靥者，须人齿散，则病药与
禀受弱人三者皆相当也，不尔，则病轻药重，反以为累后人不能究其毒瓦斯轻重，一概用药，
因兹夭横者多。昔有士贵之家，患疮疹已出而稍迟，遂用正气散加白芍药，又用胡荽酒猴梨
酒亦出迟。渠家云∶大抵医家用药太缓，自夜来烧人齿五个，酒调服之，一身疮疹俱出，骇
闻渠用，遂再诊视，脉已微，观脑后并两脚尽白色，是荣卫弱，热毒少而药力过，则阳气少
而无以应接，故无血色也。告云∶阳气尽出表外，今里寒，寒气成湿，湿必濡泻，急以二气
丹为小丸，服至半两，水泻二日方止。又服内补散治疮痘，其疮痘服人齿散，表过为斑烂，
遍体为一，将息月余方愈。其人精神稍缓，盖耗竭心液故也，详人齿治奶乳痈破肿，出箭镞
刺，表疮疹甚验。若误用早，则一变十，不可胜数，为斑烂，为虚脱，为里寒，不可不知，
又有田舍及市井间小儿，患疮痘中，行走当风，任服朴硝大黄之类无害者，恐富贵之禀，非
贫荷者比，各随宜而治。前云∶服人齿散，脉微而疮色白为外阳微，濡泻为内阴盛，自非先
用二气丹，后尚濡泻，若用之迟，岂不为虚脱也。
一百三十、内补散。治小儿正患疮疹中，或感外寒，或内伤生冷，或服冷药过多，因生
吐泻脾虚血涩，疮疹迟迟不出，肌肤瘦而无血色，里服诸调脾胃药，外服此可以滋养血气，
疮毒得出。
人参 黄 白芷 当归 肉桂 桔梗（炒） 川芎 木香 甘草（炙） 防风 浓朴
（姜制） 橘皮（去白）
上等分为细末，每服一钱，入酒二匙，温汤浸调服之，不拘时候。王子建云∶仲景论证
多而用药少，男子详而妇人略。云∶此乃穿凿之过，若使仲景存日，其方有余用。盖无坏病
矣。今则医者治病，纷纷扰扰，为利是图，动辄差误，后贤处方，救其不及，是乃方愈多，
皆是救差误尔。治疮疹用内补散，亦救其差误尔。俚俗人常云∶疮疹是热毒，见其药稍温，
便以为误，此不审之过也。殊不知伤寒是伤其寒，却有间或用大黄朴硝升麻知母之类，此皆
救一时不及。若不述此，恐人执而不移，一向偏见，使缓急疗病，意议不能完备，疑谋败事
者则多矣。
第一百二十八、活血散。治疗这种疮疹证候，皮疹发不出来，或者发出迟缓，或者发出后倒靥（皮疹消退不良）的，都适宜服用此药。
以上用白芍药炒制后研成细末，用温酒调服，如果加入一匙酒，则皮疹出得更快。如果想要止痛，只用温热水调服即可，请根据具体情况斟酌使用，这是调和营卫的药物。大概张氏《妙选方》中说：疮疹之气均匀则能发出，气行通畅，是因为营卫没有阻碍的缘故。另外芍药主治时行寒热、消除痈肿，所以能治疗疮痘。《素问》论述脚得到血液滋养就能行走，眼睛得到血液滋养就能视物，手得到血液滋养就能握持物体。《活人书》中记载一种证候感受寒邪，寸脉大尺脉弱，两足拘挛，这是因为下焦血少，不能舒展，用芍药甘草汤服用三次，随后脚就能伸直不拘挛并能行走，常用有效。又有位年长贵人不能拜跪，宣医使用六辛汤，乃是白芍药六两，甘草半两，服用十日后就能行走，这也是活血散，运行营卫的作用。
第一百二十九、人齿散。治疗疮疹已经发出但不畅快，既已发出又出现倒靥，患疮疹伴有寒热但脉搏反而迟缓的，或者因攻伐皮肤导致发出迟缓，或者面额发红，脉搏不洪大的，或者服用凉药过多，导致血涩气弱，或者皮疹发出得不畅快，隐隐约约在皮肤之间的，用酒调服。钱乙附方，治疗疮疹倒靥，加入麝香用酒调服，尤其好。又说：疮疹倒靥不出，加赤小豆七粒，用薄荷酒调服。如果是黑色的，名叫“鬼疮子”，用猪血调下二钱，过一会儿再服用。
以上用人齿脱落者，用瓷瓶密封固济，大火烧至通红，冷却后取出研为细末，用薄荷酒调服，每次半钱。过了很久脉搏平稳，毒瓦斯消散，皮疹像粟米一样发出，详细分析，这是发出疮疹的药物。如同伤寒解表的发汗药，所以伤寒发汗，必须看营卫的浅深，疮疹从表发出，必须看蕴热的多少，恐怕蕴热少而用药过重，导致斑烂的缘故。那些已经发出但不畅快的，可以用活血散、蒺藜酒、葡萄酒之类。既已发出又倒靥的，必须用人齿散，这样病、药与禀赋虚弱之人三者才能相当，不然的话，就是病轻药重，反而成为累赘。后人不能探究毒瓦斯的轻重，一概用药，因此夭折横死者很多。过去有士族富贵人家，患疮疹已经发出但稍迟，于是用正气散加白芍药，又用胡荽酒、猴梨酒，也是发出迟缓。他们家说：大抵医家用药太缓，从夜里开始烧五个牙齿，用酒调服，全身疮疹全部发出，令人惊骇听闻其用法，于是再次诊视，脉搏已经微弱，观察脑后并双脚尽是白色，这是营卫弱，热毒少而药力过猛，则阳气少而无法应接，所以没有血色。告知说：阳气尽出于体表之外，现在里寒，寒气化成湿，湿必然导致濡泻（水样腹泻），急忙用二气丹做成小丸，服用到半两，水泻两天才停止。又服用内补散治疗疮痘，其疮痘服用人齿散，表证过后变成斑烂，遍体融合为一，调养月余才痊愈。其人精神稍微缓和，大概是耗竭心液缘故，详细考察人齿治疗奶乳痈破溃肿毒，拔出箭镞刺伤，治疗疮疹非常灵验。如果误用过早，则一变十，不可胜数，导致斑烂、虚脱、里寒，不可不知。又有田舍及市井间小儿，患疮痘中，行走当风，任服朴硝大黄之类无害的，恐怕富贵之人的禀赋，不是贫苦者能比的，各自随宜而治。前文说：服人齿散，脉微而疮色白为外阳微，濡泻为内阴盛，自非先用二气丹，后来尚且濡泻，如果用之迟，岂不为虚脱吗。
第一百三十、内补散。治疗小儿正患疮疹期间，或感受外寒，或内伤生冷，或服用冷药过多，因而产生吐泻脾虚血涩，疮疹迟迟不出，肌肤消瘦而没有血色，内服各种调理脾胃的药，外服此药可以滋养血气，使疮毒透出。
人参 黄芪 白芷 当归 肉桂 桔梗（炒） 川芎 木香 甘草（炙） 防风 浓朴（姜制） 橘皮（去白）
上等分研为细末，每服一钱，加入两匙酒，用温水浸调服，不限时候。王子建说：仲景论证多而用药少，男子详而妇人略。说：这是穿凿附会的过错，假如仲景在世，他的方剂有余地可用。大概就没有坏病了。现在医生治病，纷纷扰扰，唯利是图，动辄出差错，后贤处方，补救其不及，这就是方子越多，都是补救差错罢了。治疗疮疹用内补散，也是补救其差错罢了。俚俗人常说：疮疹是热毒，见其药稍温，便以为是误治，这是不审慎的过错。殊不知伤寒是伤于寒，却有间或用大黄、朴硝、升麻、知母之类的，这都是补救一时的不及。如果不叙述这些，恐怕人固执而不改变，一向偏见，使得缓急疗病，意议不能完备，疑谋败事者就多了。
One hundred and twenty-eight, Huoxue San (Blood-Invigorating Powder). It treats this type of chuangzhen (smallpox/rubella-like eruption) syndrome where the rash fails to emerge, emerges slowly, or exhibits daoye (retraction/poor resolution after emergence). All such cases are suitable for taking this medicine.
Take Bai Shaoyao (White Peony Root, *Paeonia lactiflora*) stir-fried and ground into a fine powder. Mix with warm Jiu (Alcohol/Wine) for oral administration; adding one spoonful of wine may accelerate the emergence of the rash. If pain relief is desired, mix only with warm water for administration; please adjust according to circumstances. This is a medicine that regulates Yingwei (Nutritive and Defensive Qi). As stated in Zhang’s *Miaoxuan Fang* (Miraculous Selection Formulas): When the Qi of chuangzhen is even, it emerges; when Qi flows smoothly, it is because Yingwei are unobstructed. Furthermore, Shaoyao (Peony Root) treats epidemic chills and fever and dissipates carbuncles and swellings, thus treating chuangdou (smallpox/variolous eruptions). The *Suwen* (Plain Questions) discusses that the feet can walk when nourished by blood, the eyes can see when nourished by blood, and the hands can grasp objects when nourished by blood. In the *Heren Shu* (Book of Living People), a case describes contracting cold, with a large Cun pulse and weak Chi pulse, and spasms in both legs, attributed to deficiency of blood in the Lower Jiao preventing extension. Three doses of Shaoyao Gancao Tang (Peony and Licorice Decoction) allowed the legs to extend without spasms and enabled walking; it is commonly effective. Another case involved an elderly noble who could not kneel or bow; Physician Xuan used Lixin Tang (Six Pungent Decoction), consisting of six taels of Bai Shaoyao (White Peony Root) and half a tael of Gancao (Licorice Root). After ten days of consumption, he could walk. This too is Huoxue San, promoting the circulation of Yingwei.
One hundred and twenty-nine, Renci San (Human Tooth Powder). It treats chuangzhen that has emerged but not smoothly, or exhibits daoye (retraction) after emergence, accompanied by chills and fever but with a slow pulse. It also treats cases where purgative actions on the skin cause delayed emergence, redness on the face and forehead with a non-surging pulse, excessive intake of cooling medicines leading to stagnant blood and weak Qi, or rash emerging sluggishly, faintly visible under the skin. Administer mixed with wine. Qian Yi’s supplementary formula treats daoye of chuangzhen by adding Shexiang (Musk) and mixing with wine, which is especially good. It further states: for daoye where the rash does not emerge, add seven Chi Xiaodou (Adzuki Beans) and mix with Bohe Jiu (Mint Wine). If the color is black, it is called "Gui Chuangzi" (Ghost Eruption); administer two qian mixed with Pig Blood, and repeat after some time.
Take shed human teeth, seal them tightly in a porcelain bottle, fire intensely until red-hot, allow to cool, remove, and grind into powder. Mix with Bohe Jiu (Mint Wine) for administration, half a qian per dose. After a while, the pulse becomes calm, toxic factors disperse, and the rash emerges like millet grains. Detailed analysis shows this is a medicine to bring out chuangzhen. Similar to sweating agents for Taihan (Cold Damage) exterior syndrome, treating Taihan requires assessing the depth of Yingwei involvement; bringing out chuangzhen from the exterior requires assessing the degree of accumulated heat. One must fear that if accumulated heat is slight but medication is too heavy, it will lead to banlan (diffuse macular eruptions). For those already emerged but not smooth, Huoxue San, Jili Jiu (Tribulus Wine), or Grape Wine are suitable. For those emerged yet exhibiting daoye, Renci San is necessary, so that the disease, the medicine, and the patient’s weak constitution are appropriately matched. Otherwise, mild disease treated with heavy medicine becomes a burden. Later generations fail to investigate the severity of toxic factors and apply medicines uniformly, resulting in many premature deaths. Previously, a scholar from a wealthy family suffered from chuangzhen that emerged slightly late. He used Zhengqi San (Regular Qi Powder) plus Bai Shaoyao, and also Hui Su Jiu (Coriander Wine) and Hou Li Jiu (Monkey Pear Wine), yet emergence remained slow. His family stated: generally, physicians use medicines too mildly. Starting from nightfall, five teeth were burned and administered with wine, causing all body rashes to emerge, shocking listeners with its efficacy. Upon re-examination, the pulse was faint, and the back of the head and both feet were entirely white, indicating weak Yingwei, scant heat-toxin, and excessive medicinal force, leading to insufficient Yang Qi to respond, hence lack of blood color. It was advised: Yang Qi has exhausted itself at the exterior; now there is interior cold, transforming into dampness, which inevitably causes ru xie (watery diarrhea). Urgently administer Erqi Dan (Two Qi Pill) as small pills. After consuming half a liang, watery diarrhea stopped after two days. Subsequently, Neibu San (Interior-Nourishing Powder) was taken to treat chuangdou. Having taken Renci San, the exterior resolved into banlan (diffuse macular eruptions), merging into one mass over the whole body, requiring over a month of recuperation to heal. The person’s spirit gradually recovered, likely due to depletion of Heart fluids. Detailed examination shows Renci (Human Teeth) effectively treats mastitis with abscess rupture and extracts arrowhead splinters; it is very effective for chuangzhen. However, mistaken early use leads to exponential worsening, causing banlan, collapse, and interior cold, which must be known. There are also children in rural and market areas who, while suffering from chuangdou, walk in the wind and tolerate Puxiao (Mirabilite) and Dahuang (Rhubarb) without harm. It is feared that the constitution of the wealthy differs from the poor; treatment should follow individual suitability. As mentioned earlier: taking Renci San with a faint pulse and white rash indicates weak exterior Yang; watery diarrhea indicates abundant interior Yin. Unless Erqi Dan is used first, if diarrhea persists and treatment is delayed, it would surely lead to collapse.
One hundred and thirty, Neibu San (Interior-Nourishing Powder). It treats children currently suffering from chuangzhen who contract external cold, suffer internal injury from raw/cold foods, or take excessive cold medicines, resulting in vomiting, diarrhea, Spleen deficiency, and stagnant blood. The chuangzhen emerges slowly, the skin is emaciated and lacks blood color. While internally taking various medicines to regulate the Spleen and Stomach, externally taking this medicine can nourish Blood and Qi, allowing the chuang toxin to emerge.
Ren Shen (Ginseng Root), Huang Qi (Astragalus Root), Bai Zhi (Angelica Dahurica Root), Dang Gui (Chinese Angelica Root), Rou Gui (Cinnamon Bark), Jie Geng (Platycodon Root, stir-fried), Chuan Xiong (Sichuan Lovage Rhizome), Mu Xiang (Aucklandia Root), Gan Cao (Licorice Root, honey-fried), Fang Feng (Saposhnikovia Root), Nong Po (Magnolia Bark, ginger-processed), Ju Pi (Citrus Peel, pith removed).
Grind equal parts into a fine powder. Take one qian per dose, add two spoonfuls of wine, mix with warm water, and administer orally, regardless of timing. Wang Zijian said: Zhang Zhongjing discussed syndromes extensively but used few medicines, detailing treatments for men while briefly mentioning women. He claimed this was due to forced interpretation; had Zhang Zhongjing been alive, his formulas would have had room for application, and there would have been no "huai bing" (ruined diseases). Today, physicians treat illnesses chaotically, seeking profit, often making errors. Later sages prescribe remedies to compensate for these inadequacies; thus, more formulas exist merely to correct mistakes. Using Neibu San for chuangzhen is also correcting mistakes. Vulgar people often say: chuangzhen is a heat-toxin; seeing the medicine is slightly warm, they assume it is a mistake. This is an error of imprudence. They do not realize that Taihan (Cold Damage) is caused by cold, yet sometimes Da Huang (Rhubarb Root), Pu Xiao (Mirabilite), Sheng Ma (Cimicifuga Rhizome), and Zhi Mu (Anemarrhena Rhizome) are used. These all remedy temporary inadequacies. If these are not recorded, people may remain stubborn and biased, failing to complete comprehensive strategies for urgent and chronic care, leading to many failures due to doubt and poor planning.