人之阴气，赖胃以养。胃火上冲，肝胆之火亦相随助之，肺金之气不能下降，由清道而上冲喉咙，故
呃而有声。
邪入于胃则吐，毒犹因吐而得发越，至于干呕则重矣。总因内有伏毒，清胃自不容缓。
瘟毒移于大肠，里急后重，赤白相兼，或下恶垢，或下紫血。其人必恶寒发热，小水短缩。此热滞大
肠，只宜清热利水，其痢自止。误用通利止涩之剂不救。
毒火注于大肠，有下恶垢者，有利清水者，有倾肠直注者，有完谷不化者。此邪热不杀谷，非脾虚也，
较之似痢者稍轻。考其症，身必大热，气必雄壮，小水必短，唇必焦紫，大渴喜冷，四肢时而厥逆，腹
痛不已。此热注大肠，因其势而清利之，泄自止矣。
大肠为传送之官，欲通则易，欲实则难。杂症见此，有补有下，而疫症闭结，因毒火煎熬，大肠枯燥
不能润下，误用通利，速其死也。
小便涩赤，亦属膀胱热极，况短而且缩，其色如油乎！盖因热毒下注，结于膀胱。
小便出血，小腹必胀而痛。至于血出不痛，乃心移热于小肠，故血从精窍中来也。
猖狂刚暴，骂詈不避亲疏，甚至登高而歌，弃衣而走，逾垣上屋，非寻常力所能及，语生平未有之事、
未见之人，如有邪附者。此阳明邪热扰乱神明，病患亦不自知。多有看香、送祟、服符以驱邪者，可发一笑。
心主宰神志，心神安宁则精神清爽；若心被烈火焚烧，神志自然不清，谵语（神志不清、胡言乱语）由此产生。
人体的阴气，依赖胃气的滋养。若胃火向上冲逆，肝胆之火也会随之助长，导致肺金之气无法下降，反而沿着清道向上冲至喉咙，因此出现呃逆并伴有声音。
邪气侵入胃部则引起呕吐，毒邪或许能随呕吐而得以发散；但若仅表现为干呕，病情则更为严重。这总归是因为体内有伏留的毒邪，清泻胃火刻不容缓。
瘟毒转移至大肠，会出现里急后重（腹痛窘迫，时时欲便，肛门重坠，便出不爽），大便中赤白相兼，或者排出恶臭垢腻之物，或者排出紫黑色血液。患者必定伴有恶寒发热，小便短少。这是热邪阻滞于大肠，只宜采用清热利水的方法，痢疾自会停止。若误用通下或止涩的药物，则会导致不可挽救的后果。
毒火注人大肠，有的排出恶臭垢腻之物，有的排出清水，有的如倾盆大雨般直泻而下，有的完谷不化（食物未经消化即排出）。这是因为邪热导致食物无法被正常腐熟消化，并非脾虚所致，比那种看似痢疾的症状稍轻。考察其症状，身体必定大热，气息必定雄壮有力，小便必定短少，嘴唇必定焦黑紫暗，极度口渴且喜饮冷水，四肢时而发生厥逆（手足冰冷），腹痛不止。这是热邪注人大肠，顺应病势采用清热利下的方法，泄泻自会停止。
大肠是传导排泄的器官，想要通畅容易，想要闭塞困难。杂病中出现这种情况，有的用补法，有的用下法；但疫病中的闭结不通，是因为毒火煎熬，导致大肠干枯燥涩，不能滋润下行，此时若误用通利药物，会加速死亡。
邪气侵犯五脏，导致三阴经脉脉络不和，血液自行停滞，渗入大肠，因此血液从大便排出。
小便涩滞且颜色红赤，也属于膀胱热极的表现，何况小便短少且收缩，颜色像油一样浑浊！这是因为热毒向下灌注，结聚于膀胱。
小便出血，小腹必定胀满疼痛。至于出血而不痛，则是心将热邪移注于小肠，因此血液从尿道（精窍）中流出。
猖狂刚烈暴躁，骂人时不顾及亲疏关系，甚至登上高处唱歌，扔掉衣服奔跑，翻越墙垣屋顶，这些行为不是普通人力所能及的，说着生平从未做过的事、未见过的景象，好像有邪气附着在身上。这是阳明经的邪热扰乱了神明，患者自己也不知情。其中多有烧香拜佛、驱赶鬼祟、服用符咒以驱邪的人，这足以引人发笑。
The Heart governs the Shen (Spirit); when the Heart is tranquil, the Shen is clear and bright. If the Heart is scorched by fierce fire, the Shen becomes unclear, which gives rise to delirious speech (confused talking due to mental disorder).
The body's Yin Qi relies on the Stomach for nourishment. When Stomach Fire rushes upward, the Fire of the Liver and Gallbladder follows to assist it. Consequently, the Qi of Lung Metal cannot descend but instead rushes up along the clear pathways to the throat, resulting in hiccups accompanied by sound.
When pathogenic factors invade the Stomach, vomiting occurs; the toxin may be expelled through vomiting. However, if only dry heaving occurs, the condition is severe. This is fundamentally due to latent toxins within, making the clearing of Stomach Heat urgent.
When plague toxins shift to the Large Intestine, there is tenesmus (urgent need to defecate with a feeling of incomplete evacuation), mixed red and white discharge, or passage of foul-smelling filth or purple blood. The patient must experience aversion to cold and fever, with short, scanty urine. This indicates heat stagnation in the Large Intestine; one should only employ methods to clear heat and promote urination, after which the dysentery will cease. Misusing purgatives or astringents will lead to untreatable conditions.
When toxic fire pours into the Large Intestine, some pass foul filth, some pass clear water, some suffer from profuse direct diarrhea, and some pass undigested food. This is because pathogenic heat fails to digest food properly, not due to Spleen deficiency; it is slightly milder than cases resembling dysentery. Examining the symptoms: the body must be highly febrile, the breath vigorous, urine short, lips charred and purple, extreme thirst with preference for cold drinks, occasional coldness of the four limbs, and unceasing abdominal pain. This is heat pouring into the Large Intestine; by following the pathological trend to clear heat and promote drainage, the diarrhea will stop.
The Large Intestine is the official organ of transmission. It is easy to make it flow freely but difficult to make it obstructed. In miscellaneous diseases presenting this way, treatments include tonification or purging. However, in epidemic diseases, constipation arises because toxic fire has boiled away fluids, causing the Large Intestine to become dry and unable to lubricate downward. Misusing purgatives here accelerates death.
When pathogens invade the five Zang organs, the meridians of the three Yin channels become disharmonious, blood stagnates, and infiltrates the Large Intestine, causing blood to exit via stool.
Astringent, red urine also belongs to extreme heat in the Bladder. Moreover, if it is short and contracted, with a color like oil! This is because heat-toxin pours downward and knots in the Bladder.
Hematuria (blood in urine) implies the lower abdomen must be distended and painful. As for bleeding without pain, this is the Heart transferring heat to the Small Intestine, so blood flows from the urethra.
Frenzied, violent, and aggressive behavior, cursing without regard for kinship or distance, even climbing high places to sing, discarding clothes to run, leaping over walls and roofs—actions beyond ordinary capability—speaking of things never done or seen in one's life, as if possessed by evil spirits. This is Yangming pathogenic heat disturbing the Shen (Spirit); the patient is unaware of their own actions. Many resort to burning incense, exorcising ghosts, or taking talismans to drive out evil, which is laughable.