天门冬 麦门冬 当归 柏子仁 酸枣仁 生地黄 朱砂 丹参 元参 人参 茯神 远志 五味 桔梗
心者，神明之官。过于思虑忧愁，久久则成心劳，心劳而神明伤矣。是以怔忡健忘，目暗羞涩。且心主血，
血燥便难，血濡便润。心火不能生土，则不时不利。心虚火内灼，则口舌生疮。生地、丹、元参解心热者也。砂、
神、柏、枣仁安心神者也。天麦冬、五味合人参，清心气以生心津。远志、桔梗得当归，宽心郁而养心神。诸药
专于补心，故名。久病不瘥，必有隐情，情极则羸，会成痨瘵。痨瘵如赵养葵为治，至死只六味、八味，不知情
欲致病，责在心君。经曰∶主不明，则十二官危。处以此方，谁曰不宜。
诗曰∶天门冬闭麦门开，五味三参远载来，柏枣人归怀庆地，茯神尽教梗丹崖。
枸杞一斤，碾花椒、小茴、芝麻酒拌炒，炒毕筛净，乘干速杵成粉。再入白术、茯苓、白菊花、地黄各一两，
研
匀，蜜丸。
两肾虚损，眼花白障，此方主之。
左肾，阴水也，阴衰则阳火独治而生花；右肾，阳水也，阳衰则阴气上蒸而有障。是方四制枸杞，所以益精，
亦所以兴阳，右肾与之。术、苓、菊、地，所以利湿，亦所以生阴，左肾与之。两水既盈，五火潜息，而病亦寻
瘥。以神名丸，有以也夫。
诗曰∶枸杞新收拣一斤，椒茴麻炒杵如尘，携来苓术黄花地，炼密为丸号四神。
天门冬、麦门冬、当归、柏子仁、酸枣仁、生地黄、朱砂、丹参、元参、人参、茯神、远志、五味子、桔梗。
心，是主宰精神意识的器官。如果思虑忧愁过度，久而久之就会形成心劳（心脏功能因过度消耗而受损），心劳会导致神明（精神意识）受伤。因此会出现心悸怔忡（心中悸动不安）、健忘、视力模糊和眼部分泌物增多等症状。而且心主血脉，血燥则大便干结难解，血润则大便通畅柔和。如果心火不能温煦脾土（脾胃），就会导致排便不时顺畅或不畅。心虚导致内火灼烧，就会引起口舌生疮。生地黄、丹参、玄参是用来清除心热的药物。朱砂、茯神、柏子仁、酸枣仁是用来安定心神的药物。天门冬、麦门冬、五味子配合人参，可以清泄心气并滋生心津。远志、桔梗配合当归，能够宽解心郁并滋养心神。这些药物专门用于补益心脏，所以以此命名。久病不愈，必然有隐情，情感极度压抑会导致身体消瘦，最终演变成痨瘵（慢性虚弱性消耗性疾病，类似肺结核）。治疗痨瘵像赵养葵那样，直到死亡只使用六味地黄丸、八味地黄丸，却不明白这是由情欲致病，责任在于心君（心脏作为君主之官的主导作用）。《内经》说：“主不明，则十二官危。”处以此方，谁说它不合适呢？
诗曰：天门冬闭麦门开，五味三参远载来，柏枣人归怀庆地，茯神尽教梗丹崖。
枸杞一斤，碾碎花椒、小茴香，用芝麻酒拌炒，炒完后筛去杂质，趁干燥迅速捣成粉末。再加入白术、茯苓、白菊花、地黄各一两，研磨均匀，用蜂蜜制成丸剂。
两肾虚损，眼花、眼前有白色遮蔽物（白内障或飞蚊症等），此方主治。
左肾，属于阴水，阴气衰弱则阳气之火独盛而生花（视物如见花朵闪烁）；右肾，属于阳水，阳气衰弱则阴气上蒸而有障（眼前如有遮挡）。这个方子中经过四法炮制的枸杞，是用来补益精气的，也是用来振奋阳气的，供给右肾。白术、茯苓、菊花、地黄，是用来利湿的，也是用来滋生阴液的，供给左肾。左右两肾之水既已充盈，五脏之火自然潜藏熄灭，疾病也就随之痊愈。以“神”命名此丸，是有道理的。
诗曰：枸杞新收拣一斤，椒茴麻炒杵如尘，携来苓术黄花地，炼密为丸号四神。
Tianmendong (Asparagi Radix), Maimendong (Ophiopogonis Radix), Danggui (Angelicae Sinensis Radix), Baiziren (Platycladi Semen), Szaoren (Ziziphi Spinosae Semen), Shengdihuang (Rehmanniae Radix), Zhusha (Cinnabaris), Danshen (Salviae Miltiorrhizae Radix et Rhizoma), Yuan Shen (Scrophulariae Radix), Renshen (Ginseng Radix), Fushen (Poria cum Pinus), Yuanzhi (Polygalae Radix), Wuweizi (Schisandrae Chinensis Fructus), Jiegeng (Platycodonis Radix).
The Heart is the official responsible for the spirit and consciousness. Excessive thinking, worrying, and sorrow, over a long period, lead to "Heart Labor" (damage to heart function due to excessive consumption), which injures the spirit. Consequently, palpitations (restlessness of the heart), forgetfulness, blurred vision, and ocular discharge occur. The Heart governs blood; when blood is dry, stool becomes difficult to pass; when blood is moist, stool is soft and smooth. If Heart Fire fails to warm Spleen Earth, bowel movements may be irregular. Heart deficiency with internal fire scorching leads to sores in the mouth and tongue. Shengdihuang, Danshen, and Yuanshen clear Heart heat. Zhusha, Fushen, Baiziren, and Szaoren calm the Heart spirit. Tianmendong, Maimendong, and Wuweizi, combined with Renshen, clear Heart Qi and generate Heart fluids. Yuanzhi and Jiegeng, combined with Danggui, relieve Heart depression and nourish the Heart spirit. These herbs specialize in tonifying the Heart, hence the name. Chronic illness that does not resolve must have hidden emotional causes; extreme emotional suppression leads to emaciation and eventually consumptive disease (Lao Zhai, similar to tuberculosis). Treating Lao Zhai like Zhao Yangkui did, using only Liuwei Dihuang Wan and Bawei Dihuang Wan until death, ignores that such diseases are caused by emotional desires, and the responsibility lies with the Heart Monarch. The Classics state: "If the ruler is unclear, the twelve officials are in danger." Prescribing this formula, who would say it is inappropriate?
Poem:
Tianmendong closes, Maimendong opens,
Wuweizi and three types of Shen arrive far away,
Baiziren, Szaoren, Renshen, Danggui, and Huaiqing Dihuang,
Fushen leaves all to Gengdan Cliff.
One jin (approx. 500g) of Gouqi (Lycii Fructus), crushed together with Huajiao (Zanthoxyli Pericarpium) and Xiaohuixiang (Foeniculi Fructus), stir-fried with Sesame Wine. After frying, sift clean, and while still dry, quickly pound into powder. Then add Baizhu (Atractylodis Macrocephalae Rhizoma), Fuling (Poria), Baijuhua (Chrysanthemi Indici Flos), and Dihuang (Rehmanniae Radix praeparata), each one liang (approx. 30-37g), grind uniformly, and make pills with honey.
This formula treats deficiency and damage of both Kidneys, manifesting as blurred vision and white opacities in the eyes.
The Left Kidney is Yin Water; when Yin declines, Yang Fire dominates alone, causing visual hallucinations of flowers. The Right Kidney is Yang Water; when Yang declines, Yin Qi steams upward, causing visual obstruction. This formula uses four-processed Gouqi to benefit Essence and also to stimulate Yang, supplying the Right Kidney. Baizhu, Fuling, Ju Hua, and Dihuang promote dampness drainage and also generate Yin, supplying the Left Kidney. When the waters of both Kidneys are full, the Five Fires subside quietly, and the illness heals. Naming this pill "Shen" (Spirit/God) is justified.
Poem:
Freshly selected one jin of Gouqi,
Stir-fried with pepper, fennel, and sesame, pounded like dust,
Bring Lingzhu, Atractylodes, Chrysanthemum, and Rehmannia,
Refine honey to make pills named Four Spirits.