房弟 阴疟寒热俱重，汗多不寐，气促，腹痛大便频，左脉微软，右关尺弦长，此脾虚肝乘而心阳不摄
也。用法宜以温通甘缓，兼佐酸泄，理中汤加茯神、龙眼肉、草蔻、肉蔻、白芍。三服而神爽，痛泻止，
寒热亦减。继用归脾汤丸加山药、莲子、何首乌等，渐瘳。
毛 三疟早用截剂，寒热无定，头汗冷，呃逆，沫吐青色，面惨黑，手足厥，脉沉数小。乃邪入厥阴，
在里瘀浊上犯清道，治先通阳泄浊。用吴茱萸汤加丁香、干姜、制半夏、青皮、茯苓，浊逆已止。嗣用四逆汤，
肢和，疟二日发，用四兽饮，寒热渐轻，接服八珍丸料加首乌、牛膝、砂仁、半夏、姜汁、煮枣肉为丸。
病除。
朱 深秋疟发三阴，头眩，热甚不渴，溺痛，右脉较大。必系暑湿伏邪内蕴，昔人治疟无汗须令有汗，
乃邪从外泄。今值霜降，气令收肃，虽用辛解，邪不得越，尚难稳许愈期。紫苏、半夏、青蒿、石斛、生薏仁、
当归、鲜何首乌、知母，数服微汗，寒热减，右脉平，两关稍虚，治宜扶正兼去邪。六君子汤加鲜何首乌、
炙鳖甲、当归、知母以清透营分，加姜、枣煎服，得痊。
钱氏 怀妊六月余，客岁阴疟未止，因食牛脯，腹满不饥，谷食亦胀，致寒热沉绵，盛暑怯寒，衣絮无
汗。此卫阳大衰，腑失通降，正虚邪锢，须防胎损，治宜温卫通腑，忌用 术守补。潞参、鹿胶、当归、茯苓、
草果、煨姜、炒楂肉、半夏、陈皮。六服疟止。
族某 三日疟经年未止，处暑后燥气加临，日发寒热，食顷烦嘈干呕，色悴甚，渴眩痔痛。此燥热伤
阴，胃液虚而阴火上乘下迫也。仿甘露饮意。用生地黄（炒）、知母（酒炒）、麦冬、石斛、花粉、生白芍、
阿胶（水化），数服症退，用何人饮疟止。
朱 三阴疟发日晏，脘痞呕酸，乃半夏泻心汤症耳。犹服知母、乌梅、穿山甲等苦酸透络截剂，遂令
寒热无汗，三日两发，
舌有蟹爪纹，是脾脏寒水旁溢支络，别成窠臼，一增为两，求轻反重矣。宜六君子汤温脾以运湿，水湿去则寒
热轻，不致邪伤肝肾，延成羸怯。潞参、于术、云苓、陈皮、半夏姜制、砂仁、草果、煨姜。数服已去其一，
仍二日一发，又数服，发益早，即寒热亦微。以原方药制末，加牛膝（炒），去草果，用姜汁和枣肉为丸，服
愈。
房弟 三日疟初发，寒痰甚多。先令将陈香橼去蒂，纳明雄黄（五钱，水飞研），炭火 （勿令烟泄），
存性，共研细，空心开水下。卧片时，以箸探吐痰涎，再服再吐，（能吐出胶痰更好。）吐半日，饮粥汤吐
止，病愈后，调补元气以杜复发。
李 患前症夜发。用何首乌散，后以劳力鼻衄，寒止热甚，治宜和阴透邪。乌梅肉（二钱）、白芍（三钱）、
知母（酒炒，钱半）、鳖甲（炙，三钱）、生首乌（四钱）、生地黄（二钱半）、牛膝（酒蒸，钱半），
数服而止。（此酸味可以和阴，阴药可以透邪。）
秦 阴疟误药，寒热缠绵，无汗，面浮腹肿，眼色如金，肉黄便泻，脉左沉缓，右虚濡，水湿渍里溢肤，
势成痞胀。用分消法。大腹皮、茵陈、制半夏、生薏仁、茯苓（各二钱）、苏梗、陈皮、谷芽（各一钱）、
枳壳、砂仁（各八分）、浓朴（五分）、姜（三钱）、车前子（五分），溺爽汗出，诸症俱退，去苏梗、枳、
朴、加鸡内金（炙三钱）、于术（炒一钱。）仿利水实脾法得愈。
房某之弟：患阴疟，寒战与发热均严重，汗出多且失眠，气短促，腹痛伴大便次数增多。左脉微弱柔软，右关尺部脉象弦长。此为脾虚导致肝木乘克，且心阳不能固摄所致。治疗法则宜采用温通、甘缓之法，兼佐以酸味泄降之品。处方用理中汤加茯神、龙眼肉、草蔻、肉蔻、白芍。服用三剂后精神清爽，腹痛腹泻停止，寒热症状亦减轻。继服归脾汤丸剂加山药、莲子、何首乌等药，逐渐痊愈。
毛某：患三日疟，早期误用截疟药物，导致寒热发作无定时，头部出汗且冷汗，呃逆，呕吐青色泡沫，面色惨黑，手足厥冷，脉象沉数而细小。这是邪气深入厥阴经，在里的瘀浊之气上犯清窍所致。治疗应先通阳泄浊。使用吴茱萸汤加丁香、干姜、制半夏、青皮、茯苓，浊逆之气已止。随后改用四逆汤，四肢转温，疟疾改为两日一发，再用四兽饮，寒热逐渐减轻。接着服用八珍丸料加何首乌、牛膝、砂仁、半夏、姜汁、煮枣肉制成丸药，病除。
朱某：深秋时节疟疾发作于三阴经，头晕目眩，发热重但不口渴，小便疼痛，右脉较大。必定是暑湿伏邪内蕴所致。古人治疟疾若无汗，须令其发汗，使邪气从体表外泄。如今正值霜降节气，气候收敛肃杀，即使使用辛散解表药，邪气也难以透达，尚难保证确切痊愈日期。用紫苏、半夏、青蒿、石斛、生薏仁、当归、鲜何首乌、知母，服用数剂后微汗出，寒热减轻，右脉平和，两关部稍显虚弱，治疗宜扶正兼去邪。用六君子汤加鲜何首乌、炙鳖甲、当归、知母以清透营分，加生姜、大枣煎服，得以痊愈。
钱氏（女性）：怀孕六个多月，去年患阴疟未愈，因食用牛肉干，导致腹部胀满不思饮食，吃谷物食物也觉胀闷，致使寒热缠绵不断，盛夏时节却怕冷，穿棉絮衣物仍无汗。此为卫阳大衰，腑气失于通降，正气虚弱邪气锢结，须防止胎元受损，治疗宜温补卫阳、通降腑气，忌用白术等守补之品。用潞参、鹿角胶、当归、茯苓、草果、煨姜、炒山楂肉、半夏、陈皮。服用六剂后疟疾停止。
同族某人：患三日疟经年未愈，处暑后燥气加重，每日发作寒热，进食片刻后心烦嘈杂并干呕，神色憔悴严重，口渴、眩晕、痔疮疼痛。此为燥热伤阴，胃液亏虚而阴火上冲下迫所致。仿照甘露饮之意。用生地黄（炒）、知母（酒炒）、麦冬、石斛、花粉、生白芍、阿胶（水化），服用数剂症状消退，后用何人饮疟疾停止。
朱某：三阴疟发作时间日益推迟，胃脘痞闷、呕吐酸水，本是半夏泻心汤证。却继续服用知母、乌梅、穿山甲等苦酸透络截疟药，遂致寒热无汗，三日发作两次，舌面出现蟹爪纹，这是脾脏寒水旁溢支络，另成窠臼，病情由一增为二，求轻反重。宜用六君子汤温脾以运化湿气，水湿去除则寒热减轻，不致使邪气损伤肝肾，拖延成羸弱怯症。用潞参、于术、云苓、陈皮、姜制半夏、砂仁、草果、煨姜。服用数剂后去除了三分之一病程，仍两日一发，又服数剂，发作时间提前，即寒热也变轻微。将原方药制成粉末，加炒牛膝，去掉草果，用姜汁和枣肉制成丸药，服用痊愈。
房某之弟：三日疟初发，寒痰甚多。先令取陈香橼去蒂，纳入明雄黄（五钱，水飞研细），用炭火煅烧（勿让烟泄露），存性，共研细末，空腹开水送服。躺片刻后，用筷子探喉催吐痰涎，再服再吐（能吐出胶状痰更好）。吐了半日，喝粥汤后停止呕吐，病愈后，调补元气以防复发。
李某：患前症夜间发作。用何首乌散，后因劳累导致鼻出血，寒战停止但发热严重，治疗宜调和阴液透达邪气。用乌梅肉（二钱）、白芍（三钱）、知母（酒炒，钱半）、鳖甲（炙，三钱）、生首乌（四钱）、生地黄（二钱半）、牛膝（酒蒸，钱半），服用数剂而止。（此酸味可以调和阴液，阴药可以透达邪气。）
秦某：阴疟误治用药，寒热缠绵，无汗，面部浮肿腹部肿胀，眼色如金，肌肉发黄大便泄泻，脉象左沉缓，右虚濡，水湿浸渍体内溢于皮肤，势成痞胀。用分消法。用大腹皮、茵陈、制半夏、生薏仁、茯苓（各二钱）、苏梗、陈皮、谷芽（各一钱）、枳壳、砂仁（各八分）、浓朴（五分）、姜（三钱）、车前子（五分），小便通畅汗出，诸症俱退，去掉苏梗、枳壳、厚朴，加鸡内金（炙三钱）、于术（炒一钱）。仿利水实脾法得以痊愈。
Patient Fang's younger brother: Suffered from Yin malaria, with severe chills and fever, profuse sweating, insomnia, shortness of breath, abdominal pain accompanied by frequent stools. The left pulse was weak and soft; the right Guan and Chi positions showed a wiry and long pulse. This indicates Spleen deficiency leading to Liver Wood overacting on Earth, and Heart Yang failing to secure and control. The treatment principle should employ warming and unblocking, sweet and缓和 (soothing) methods, assisted by sour astringents to drain downward. The prescription used Lizhong Tang (Regulate the Middle Decoction) added with Fushen (Poria with Hostwood), Longyanrou (Longan Aril), Cao Kou (Nutmeg Seed), Rou Kou (Nutmeg), and Baishao (White Peony Root). After three doses, mental clarity returned, abdominal pain and diarrhea ceased, and chills and fever also decreased. Subsequently, Guipi Wan (Restore the Spleen Pill) added with Shanyao (Chinese Yam), Lianzi (Lotus Seed), and Heshouwu (Polygonum Multiflorum Root) was taken gradually until recovery.
Patient Mao: Suffered from tertian malaria. Early use of antimalarial agents resulted in irregular chills and fever, cold sweat on the head, hiccups, vomiting of green froth, a ghastly black complexion, cold extremities, and a deep, rapid, small pulse. This signifies pathogenic factors entering the Jueyin channel, where internal stasis and turbidity rise to invade the clear orifices. Treatment should first focus on unblocking Yang and draining turbidity. Wuzhuyu Tang (Evodia Decoction) added with Dingxiang (Clove), Ganjiang (Dried Ginger), Zhibanxia (Prepared Pinellia Rhizome), Qingpi (Green Tangerine Peel), and Fuling (Poria) was used, stopping the turbid rebellion. Thereafter, Sini Tang (Frigid Extremities Decoction) was employed; limbs became warm, and malaria shifted to every other day. Six Beasts Drink (Sishou Yin) was then used, gradually alleviating chills and fever. Finally, Bazhen Wan material (Eight Treasures Pill base) added with Heshouwu, Niuxi (Achyranthes Root), Sharen (Amomum Fruit), Banxia, Jiangzhi (Ginger Juice), and boiled Jiazrou (Date Flesh) was made into pills. The disease was cured.
Patient Zhu: Malaria occurred in late autumn affecting the Three Yin channels, presenting with dizziness, intense heat without thirst, painful urination, and a larger right pulse. This must be due to summer-heat and dampness latent pathogens accumulating internally. Ancients treated malaria without sweating by inducing perspiration so that pathogens could escape from the exterior. Now, at the Frost Descent solar term, the climate is converging and肃 (desolate/cold); even with acrid-releasing herbs, pathogens cannot vent outward, making a definite prognosis for cure difficult. Zisu (Perilla Leaf), Banxia, Qinghao (Sweet Wormwood), Shihu (Dendrobium Stem), Sheng Yiren (Raw Coix Seed), Danggui (Angelica Sinensis), Xian Heshouwu (Fresh Polygonum Multiflorum Root), and Zhimu (Anemarrhena Rhizome) were used. After several doses, slight sweating occurred, chills and fever reduced, the right pulse normalized, but both Guan positions remained slightly deficient. Treatment should support healthy Qi while eliminating pathogens. Liujunzi Tang (Six Gentlemen Decoction) added with Xian Heshouwu, Zhi Biejia (Baked Turtle Shell), Danggui, and Zhimu was used to clear and vent the Ying (Nutritive) level, with Shengjiang (Fresh Ginger) and Dazao (Jujube) added for decoction. Recovery was achieved.
Ms. Qian: Pregnant for over six months, she had not recovered from Yin malaria last year. Due to eating beef jerky, she developed abdominal fullness, anorexia, and bloating after eating grains, leading to lingering chills and fever. Despite the peak of summer, she feared cold, wore cotton padding, yet had no sweat. This indicates severe decline of Wei (Defensive) Yang, failure of the Fu organs to descend and circulate, deficiency of Zheng Qi (Upright Qi) with entrenched pathogens. Care must be taken to prevent fetal damage. Treatment should warm the Wei and unblock the Fu organs; caution against using Atractylodes (Zhu Ru/Bai Zhu) which retains and tonifies stagnation. Lushen (Codonopsis Root), Lu Jiao Jiao (Deer Antler Glue), Danggui, Fuling, Caoguo (Black Cardamom), Wei Jiang (Roasted Ginger), Chao Zhangrou (Stir-fried Hawthorn Flesh), Banxia, and Chenpi (Tangerine Peel) were used. After six doses, malaria stopped.
Relative: Suffering from tertian malaria for years without cessation. After the End of Heat solar term, dryness intensified, causing daily chills and fever. Within moments of eating, he felt irritability, epigastric discomfort, and dry retching. His complexion was extremely sallow, accompanied by thirst, dizziness, and hemorrhoid pain. This indicates dryness-heat injuring Yin, with deficiency of Stomach fluids allowing Deficient Fire to ascend and press downward. Following the intent of Ganlu Yin (Sweet Dew Drink), Sheng Dihuang (Raw Rehmannia Root), Zhimu (wine-fried), Maidong (Ophiopogon Tuber), Shihu, Huafen (Trichosanthes Root), Sheng Baishao (Raw White Peony Root), and Ejiao (Donkey-hide Gelatin dissolved in water) were used. Symptoms subsided after several doses; Hetou Yin (He Ren Yin) was then used to stop the malaria.
Patient Zhu: The onset of Three Yin malaria was delayed daily, accompanied by epigastric stuffiness and sour regurgitation, indicating a Banxia Xiexin Tang (Pinellia Decoct to Drain the Epigastrium) pattern. However, bitter-acid collaterals-penetrating antimalarial agents like Zhimu, Wu Mei (Mume Fruit), and Chuanshanjia (Pangolin Scales) were still taken, resulting in chills and fever without sweat, occurring twice in three days. Crab-claw patterns appeared on the tongue, indicating Cold Water of the Spleen overflowing into collateral branches, forming new pathological foci. The condition worsened from one manifestation to two, seeking lightness but gaining heaviness. Liujunzi Tang (Six Gentlemen Decoction) should be used to warm the Spleen and transform dampness. Once water-dampness is removed, chills and fever will lighten, preventing pathogenic invasion of the Liver and Kidney, which would prolong into emaciation and weakness. Lushen, Yuzhu (Atractylodes Macrocephala), Yunling (Poria), Chenpi, Jiang-zhi Banxia (Ginger-processed Pinellia), Sharen, Caoguo, and Wei Jiang were used. After several doses, one-third of the course was eliminated, though it still occurred every other day. After more doses, attacks occurred earlier, and chills/fever became milder. The original formula was processed into powder, added with Chao Niuxi (Stir-fried Achyranthes), Caoguo removed, and mixed with Jiangzhi and Jiazrou to form pills. Taken to cure.
Patient Fang's younger brother: Initial onset of tertian malaria with excessive cold phlegm. First, aged Xiangyuan (Citron fruit) was prepared by removing the stem, filled with Ming Xionghuang (Realgar, 5 qian, water-ground and powdered), calcined over charcoal fire (preventing smoke leakage) to preserve its nature, then ground together into fine powder. Taken with warm water on an empty stomach. After lying down for a while, a chopstick was used to induce vomiting of phlegm-saliva. Repeat administration and induction (better if gelatinous phlegm is expelled). After half a day of vomiting, porridge soup was drunk to stop vomiting. Post-cure, Yuan Qi (Primordial Qi) was regulated and supplemented to prevent recurrence.
Patient Li: Suffered from the aforementioned symptoms occurring at night. Hetou San (Hetou Powder) was used. Later, due to labor, he suffered epistaxis; chills stopped but fever intensified. Treatment should harmonize Yin and vent pathogens. Wu Mei Rou (Mume Flesh, 2 qian), Baishao (3 qian), Zhimu (wine-fried, 1.5 qian), Biejia (roasted, 3 qian), Sheng Shouwu (4 qian), Sheng Dihuang (2.5 qian), and Niuxi (wine-steamed, 1.5 qian) were used. Cured after several doses. (Note: Sour flavors can harmonize Yin; Yin-nourishing herbs can vent pathogens.)
Patient Qin: Yin malaria mismanaged with medication, resulting in lingering chills and fever, no sweat, facial edema, abdominal swelling, yellow eyes (jaundice), yellowish skin, and diarrhea. Left pulse was deep and slow; right pulse was deficient and soggy. Water-dampness soaked internally and overflowed to the skin, threatening pi-zhang (abdominal distension). Fenxiao Fa (Separating and Eliminating Method) was applied. Dafupi (Areca Peel), Yinchen (Artemisia Capillaris), Zhibanxia, Sheng Yiren, Fuling (each 2 qian), Sugeng (Perilla Stem), Chenpi, Guya (Sprouted Grain, each 1 qian), Zhike (Bitter Orange), Sharen (each 0.8 fen), Houpo (Magnolia Bark, 0.5 fen), Jiang (3 qian), and Cheqianzi (Plantago Seed, 0.5 fen) were used. With smooth urination and sweating, all symptoms receded. Sugeng, Zhike, and Houpo were removed; Ji Neijin (Chicken Gizzard Lining, roasted 3 qian) and Yuzhu (stir-fried 1 qian) were added. Recovered following the method of promoting diuresis and strengthening the Spleen.