柴胡半斤 桂枝三两（去皮） 干姜二两 黄芩三两 栝蒌根四两 牡蛎三两（熬） 甘
草
二两
上七味，以水一斗二升，煮取六升，去滓，再煎取三升，温服一升，日三服。初服微烦，
复
夏月，暑邪先伤在内之伏阴，至秋复感凉风，更伤卫阳，其疟寒多微有热，显然阴阳无
争，
柴胡
即用
药独
常山一钱 槟榔二钱 草果一钱 浓朴一钱 黄芩一钱五分 知母二钱 石菖蒲七分
青皮
上水二钟，煎八分，露一宿，发后温服。
疟发间日者，《内经》言∶邪气内薄五脏，横连募原（全元起本“募”作“膜”），其道
远，
《圣
表，
《
胃
浓朴温除肠胃之浊邪，黄芩、知母清理肠胃之热邪，复以菖蒲透膜，青皮达下，甘草和中，
而疟自解。
菊花四十分 白术十分 细辛三分 茯苓三分 左牡蛎三分 桔梗八分 防风十分 人
参三
上十四味，杵为散，酒服方寸匕，日三服。初服二十日，用温酒调服。禁一切鱼、肉、
大蒜
程云来云∶《金匮》候氏黑散，系宋人较正附入唐人之方，因逸之，其辨论颇详。而喻
嘉言
冷服
诚
药多炒黑，不从气而从味，取其苦涩以走于空窍耳。再读方下云，初服二十日，用温酒调，
是不欲其遽填也；后服六十日，并禁热食，则一任填空窍矣。夫填窍本之《内经》久塞其空
，是谓良工之语，煞有来历，余故选之。
柴胡半斤，桂枝三两（去皮），干姜二两，黄芩三两，栝蒌根四两，牡蛎三两（熬制），甘草二两。
以上七味药，用水一斗二升，煎煮至剩余六升，滤去药渣，再次煎煮至剩余三升，每次温服一升，每日服用三次。初次服药后会有轻微烦闷感，这是正常现象。
夏季，暑邪先损伤体内潜伏的阴气，到了秋季又感受凉风，进一步损伤卫阳之气，导致疟疾表现为寒多热少，这显然是阴阳之气没有激烈争斗的表现。
柴胡汤（Chaihu Tang, Bupleurum Decoction）即使用药独……（原文此处似有缺漏或断句不清，依文意推测为讨论柴胡类方剂的运用）。
常山一钱，槟榔二钱，草果一钱，厚朴一钱，黄芩一钱五分，知母二钱，石菖蒲七分，青皮……（原文此处似有缺漏）。
以上药物用水两钟，煎煮至八分，露天放置一夜，疟疾发作后温服。
疟疾每隔一日发作一次的，《黄帝内经》认为：邪气内迫五脏，横向连接募原（全元起本中“募”写作“膜”），病位深远，……《圣济总录》……表证……《……》胃……
厚朴能温散肠胃中的浊邪，黄芩、知母能清理肠胃中的热邪，再用石菖蒲透达膜原，青皮通达下焦，甘草调和脾胃，这样疟疾自然解除。
菊花四十分，白术十分，细辛三分，茯苓三分，左牡蛎三分，桔梗八分，防风十分，人参三分……（原文此处似有缺漏）。
以上十四味药，捣碎成散剂，用酒送服一方寸匕，每日服用三次。初次服用二十天，用温酒调服。禁止食用一切鱼、肉、大蒜等食物。
程云来说：《金匮要略》中的候氏黑散，是宋代人校正并附入唐代医家的方剂，因为遗失了部分内容，其辨析论述颇为详细。而喻嘉言……冷服……确实……药物多炒黑，不取其气而取其味，利用其苦涩之性以走窜空窍。再读方剂下方的说明，初次服用二十天，用温酒调服，是不希望其迅速填塞；后续服用六十天，并禁止热食，则是任由药物填补空窍。填补空窍的理论源自《黄帝内经》“久塞其空”，这是良医的话语，确有来历，所以我选择收录此方。
Bupleuri Radix (Chaihu) 8 liang, Cinnamomi Ramulus (Guizhi) 3 liang (bark removed), Zingiberis Rhizoma Recens (Ganjiang) 2 liang, Scutellariae Radix (Huangqin) 3 liang, Tetrastigomatis Radix et Caulis (Gualougen) 4 liang, Ostreae Concha (Muli) 3 liang (calcined), Glycyrrhizae Radix et Rhizoma (Gancao) 2 liang.
The above seven herbs are decocted in 12 sheng of water until reduced to 6 sheng. The dregs are strained out, and the liquid is further concentrated by boiling until 3 sheng remain. Take 1 sheng warm, three times a day. Mild irritability may occur after the first dose.
In summer, pathogenic heat (Shu-xie) first damages the latent Yin within the body; in autumn, exposure to cool wind further injures the Defensive Yang (Wei-yang). This results in malaria with predominant chills and slight fever, indicating that there is no intense struggle between Yin and Yang.
Chaihu Tang (Chaihu Tang, Bupleurum Decoction) is used... [Text fragment]
Dichroae Radix (Changshan) 1 qian, Arecae Semen (Binglang) 2 qian, Tsaoko Fructus (Caoguo) 1 qian, Magnoliae Officinalis Cortex (Houpo) 1 qian, Scutellariae Radix (Huangqin) 1.5 qian, Anemarrhenae Rhizoma (Zhimu) 2 qian, Acori Tatarinowii Rhizoma (Shichangpu) 0.7 qian, Citri Reticulatae Pericarpium Viride (Qingpi)... [Text fragment].
Decoct the above herbs in two zhong of water until reduced to eight parts. Leave exposed overnight. Take warm after the malaria attack subsides.
For malaria occurring every other day, the *Neijing* states: "Pathogenic factors invade internally towards the five Zang organs and extend horizontally to connect with the Mu-Yuan (Mo-Yuan)" (In Quan Yuanqi's edition, "Mu" is written as "Mo"). The pathway is distant... [Text fragment] *Shengji Zonglu*... Exterior syndrome... [Text fragment] Stomach...
Houpo (Magnoliae Officinalis Cortex) warms and disperses turbid pathogens in the intestines and stomach; Huangqin (Scutellariae Radix) and Zhimu (Anemarrhenae Rhizoma) clear heat pathogens from the intestines and stomach; Shichangpu (Acori Tatarinowii Rhizoma) penetrates the membranes; Qingpi (Citri Reticulatae Pericarpium Viride) reaches the lower jiao; Gancao (Glycyrrhizae Radix et Rhizoma) harmonizes the middle jiao. Thus, the malaria resolves naturally.
Chrysanthemi Flos (Juhua) 40 fen, Atractylodis Macrocephalae Rhizoma (Baizhu) 10 fen, Asari Radix et Rhizoma (Xixin) 3 fen, Poria (Fuling) 3 fen, Ostreae Concha (Muli) 3 fen (left side), Platycodonis Radix (Jiegeng) 8 fen, Saposhnikoviae Radix (Fangfeng) 10 fen, Ginseng Radix (Renshen) 3 fen... [Text fragment].
Grind the above fourteen herbs into a powder. Administer one fangcun bi (a square-inch measure) with wine, three times a day. For the first twenty days, take with warm wine. Avoid all fish, meat, and garlic.
Cheng Yunlai stated: Houshi Heisan (Houshi Black Powder) in the *Jinkui Yaolue* was corrected and appended by Song dynasty scholars to formulas of Tang dynasty physicians. Due to missing content, its commentary is quite detailed. Yu Jiayan... cold administration... Indeed... Most herbs are stir-fried until black, relying on their flavor rather than their qi, utilizing their bitter and astringent properties to enter the empty orifices. Furthermore, reading the instructions below the formula: taking it with warm wine for the first twenty days prevents rapid clogging; subsequent administration for sixty days, while avoiding hot food, allows the medicine to fill the orifices freely. The concept of filling orifices originates from the *Neijing*: "Longly obstructing the emptiness." This is the words of a skilled physician, with genuine historical precedence, which is why I selected it.