五脏有六腑六腑有十二原十二原出于四关主治五脏五脏有疾当取之十二原十二原者五脏
之所
以禀三百六十五节气味也五脏有疾应出十二原而原各有出阳中之少阴肺也其原出于太渊阳中
之太阳心也其原出于大陵阴中之少阳肝也其原出于太冲阴中之至阴脾也其原出于太白阴中之
太阴肾也其原出于太溪膏之原出于鸠尾肓之原出于气海此十二原主治五脏六腑之有疾也(灵
枢)○四关者合谷太冲穴也十二经原皆出于四关(入门)
五脏 二十五穴六腑 三十六穴并巨虚上下廉共六十四 实切要之穴也脏腑有病此六十
四穴
皆主之其太渊太陵太冲太白太溪为五脏之原其三里巨虚上下廉委中委阳阳陵泉为六腑之合又
切要中之切要而医所最当先者也(藏 二十五府 三十六合为六十一 加委阳上廉下廉是为
六十四 也纲目)
帝曰荣 与合各有名乎岐伯曰荣 治外经合治内府帝曰合各有名乎岐伯曰胃合入于三里
大肠
合入于巨虚上廉小肠合入于巨虚下廉此三府皆出足阳明也三焦合入于委阳膀胱合入于委中此
二府皆出足太阳也胆合入于阳陵泉此一府出足少阳也帝曰取之奈何岐伯曰取三里者低跗取
之
取巨虚者举足取之委阳者屈伸而索之委中者屈而取之阳陵泉者正竖膝与之脐下至委阳之阳取
之(灵枢)
五脏各有对应的六腑，六腑共有十二个原穴。这十二个原穴出于四肢肘膝关节以下的“四关”部位，主治五脏的疾病。当五脏发生病变时，应当选取这十二个原穴进行治疗。所谓十二原穴，是五脏之气禀受三百六十五节气味的所在之处。五脏有病，其病气会反映在十二原穴上，而每个原穴都有其特定的出处：位于阳中的少阴经肺脏，其原穴出于太渊；位于阳中的太阳经心脏，其原穴出于大陵（注：此处原文有误，心之原穴应为神门，大陵为心包络原穴，但依原文翻译）；位于阴中之少阳经肝脏，其原穴出于太冲；位于阴中之至阴经脾脏，其原穴出于太白；位于阴中之太阴经肾脏，其原穴出于太溪。膏的根源出自鸠尾，肓的根源出自气海。这十二个原穴主治五脏六腑的疾病。（引自《灵枢》）○所谓的“四关”，是指合谷和太冲这两个穴位。十二经脉的原穴都出于四关。（引自《入门》）
五脏有二十五个原穴，六腑有三十六个合穴，加上上巨虚和下巨虚两个穴位，共计六十四个切实重要的穴位。脏腑发生疾病时，这六十四个穴位都可以主治。其中，太渊、太陵、太冲、太白、太溪是五脏的原穴；足三里、上巨虚、下巨虚、委中、委阳、阳陵泉是六腑的合穴。这些更是重要穴位中的重要穴位，是医生最应当首先掌握的。（五脏二十五穴，六腑三十六合穴，共六十一穴，再加上委阳、上廉、下廉三穴，共计六十四穴。）（引自《纲目》）
黄帝问：荣穴与合穴各自有什么名称呢？岐伯回答：荣穴治疗外经的病证，合穴治疗内腑的病证。黄帝又问：合穴各自叫什么名字呢？岐伯说：胃的合穴进入足三里；大肠的合穴进入上巨虚；小肠的合穴进入下巨虚。这三个腑都归属于足阳明胃经。三焦的合穴进入委阳；膀胱的合穴进入委中。这两个腑都归属于足太阳膀胱经。胆的合穴进入阳陵泉。这一个腑归属于足少阳胆经。黄帝问：如何取用这些穴位呢？岐伯说：取足三里穴时，需低伏脚背来寻找；取上巨虚和下巨虚穴时，需抬起脚来寻找；取委阳穴时，需屈伸腿部来探寻；取委中穴时，需弯曲膝盖来寻找；取阳陵泉穴时，需正坐竖膝，从脐下至委阳的阳侧来寻找。（引自《灵枢》）
The five Zang organs correspond to the six Fu organs, and the six Fu organs have twelve Yuan-source points. These twelve Yuan-source points emerge from the "Four Passes" (Sìguān) located at the elbows and knees, and they govern diseases of the five Zang organs. When diseases occur in the five Zang organs, one should select these twelve Yuan-source points for treatment. The so-called twelve Yuan-source points are where the Qi of the five Zang organs receives and distributes the essence from the three hundred and sixty-five acupoints. When diseases arise in the five Zang organs, their pathological changes manifest at the twelve Yuan-source points, each having its specific location: For the Lung, a Shaoyin organ within Yang, its Yuan-source point emerges from Taiyuan (LU-9); for the Heart, a Taiyang organ within Yang, its Yuan-source point emerges from Daling (PC-7); for the Liver, a Shaoyang organ within Yin, its Yuan-source point emerges from Taichong (LR-3); for the Spleen, a Zhìyīn organ within Yin, its Yuan-source point emerges from Taibai (SP-3); for the Kidney, a Taiyin organ within Yin, its Yuan-source point emerges from Taixi (KI-3). The source of the Gao (膏, deep fat/marrow) emerges from Jiutui (CV-15), and the source of the Huang (肓, diaphragm/abdominal cavity) emerges from Qihai (CV-6). These twelve Yuan-source points treat diseases of the five Zang and six Fu organs (Ling Shu). ○ The "Four Passes" refer to Hegu (LI-4) and Taichong (LR-3). The Yuan-source points of the twelve meridians all emerge from the Four Passes (Ru Men).
There are twenty-five Yuan-source points for the five Zang organs and thirty-six He-sea points for the six Fu organs. Together with Shangjuxu (ST-37) and Xiajuxu (BL-39), there are sixty-four essential and crucial points. When diseases affect the Zang and Fu organs, these sixty-four points can all be used for treatment. Among them, Taiyuan (LU-9), Daling (PC-7), Taichong (LR-3), Taibai (SP-3), and Taixi (KI-3) are the Yuan-source points of the five Zang organs; Zusanli (ST-36), Shangjuxu (ST-37), Xiajuxu (BL-39), Weizhong (BL-40), Weiyang (BL-39), and Yanglingquan (GB-34) are the He-sea points of the six Fu organs. These are the most crucial among the crucial points and are what physicians must master first (Zang organs have twenty-five points, Fu organs have thirty-six He-sea points, totaling sixty-one points; adding Weiyang, Shanglian, and Xialian makes sixty-four points) (Gang Mu).
The Yellow Emperor asked: Do Ying-spring points and He-sea points have distinct names? Qibo replied: Ying-spring points treat disorders of the exterior meridians, while He-sea points treat disorders of the interior Fu organs. The Yellow Emperor asked again: What are the specific names of the He-sea points? Qibo said: The He-sea point of the Stomach enters Zusanli (ST-36); the He-sea point of the Large Intestine enters Shangjuxu (ST-37); the He-sea point of the Small Intestine enters Xiajuxu (BL-39). These three Fu organs belong to the Foot-Yangming Stomach Meridian. The He-sea point of the Sanjiao (Triple Burner) enters Weiyang (BL-39); the He-sea point of the Bladder enters Weizhong (BL-40). These two Fu organs belong to the Foot-Taiyang Bladder Meridian. The He-sea point of the Gallbladder enters Yanglingquan (GB-34). This one Fu organ belongs to the Foot-Shaoyang Gallbladder Meridian. The Yellow Emperor asked: How should these points be accessed? Qibo said: To access Zusanli (ST-36), depress the dorsum of the foot to locate it; to access Shangjuxu and Xiajuxu, elevate the foot to locate them; to access Weiyang, flex and extend the leg to search for it; to access Weizhong, flex the knee to locate it; to access Yanglingquan, sit upright with knees vertical, locating it below the navel towards the Yang side of Weiyang (Ling Shu).