(昏愦 旧以叉手冒心滥入今去之)
成 郁为郁结而气不舒冒为昏冒而神不清俗谓之昏迷是也皆因虚乘寒所致经曰诸虚乘寒者则为厥郁冒不仁此寒气
乘虚中上也骆龙吉以附子汤倍人参川芎天麻干姜之类主之又曰太阳病先下之不解因复发汗以此表里俱虚其人因冒冒家
汗出自愈由表和也若不得汗不解者以人参三白汤加川芎天麻如下虚脉微者加附子以温肾经乃固本也经曰滋苗者必固本
伐下者枯其上此之谓也要略曰新产妇人有三病一茎二郁冒三大便难亡血复汗寒多郁冒又曰产妇郁冒其脉微弱不能食大
便坚者盖由血虚而厥厥而必冒冒家欲解必大汗出观此则郁冒为虚寒可知矣又少阴病下利止而头眩时时自冒者死以其虚
极而脱也
太阳 病先下之而不愈因复发汗以此表里俱虚其人因致冒冒家汗出自愈所以然者汗出表和故也里未和然后复下之
(成氏以郁训冒疑未莹按说文冒字从曰从目曰即小儿及蛮夷头衣也此致冒者谓若物蒙蔽其目也是昏迷之义今以冒为郁
不惟失六书之本旨且失病情及仲景之意也里未和时刻作得里和或增未字而不去得字则舛于文理今以宋本正之)诸乘寒者
则为厥郁冒不仁口急不能言战栗也
太阳与少阳并病头项强痛或眩冒时如结胸心下痞硬者当刺大椎肺俞肝俞(详项强)
阳明 病患小便不利大便乍难乍易时有微热喘冒不能卧有燥屎也宜大承气汤
少阴 病但欲寐下利止而头眩时时自冒者死
厥阴 下利清谷脉沉迟其人面赤身有微热必郁冒汗出而解(详下利)
伤寒吐下后虚烦脉其微八九日心下痞硬胁下痛气上冲咽喉眩冒经脉动惕者久而成痿
海 伤寒传至五六日间渐变神昏不语或睡中独语一二句目赤唇焦舌干不饮水稀粥与之则咽不与则不思六脉细数而
不洪大心下无痞腹中不满大小便如常或传至十日以来形貌如醉医见神昏不已多用大承气汤下之则误矣盖不知此热传手
少阴心经也然又未知其何经而来答曰本太阳经伤风风为阳邪伤卫阴血自燥热结膀胱壬病逆传于丙丙丁兄妹由是传心心
火自上迫熏肺所以神昏也盖肺为清肃之脏内有火邪故令神昏宜栀子黄连黄芩汤若脉在丙者导赤散脉在丁者泻心汤若误
用凉膈散此乃气中之血药也如右手寸脉沉滑有力者则可用之或用犀角地黄汤近于是已本方所说若无犀角以升麻代之是
阳明经药也此解阳明经血中热药若脉浮沉俱有力者是丙丁俱有热可以导赤散泻心汤各半服之则宜矣此证膀胱传丙足传
手经者下传上也丙传丁者表传里也壬传丁者艮传离也越经传者又为腑传脏也活人云伤寒只传足经不传手经者此言不尽
意也有从足经而传手经者何以知之经云伤寒或止传一经或间传三经不可一途取之但视其脉与外证治之此活法也与食则
咽者邪不在胃也不与则不思者以其神昏故也邪热既不在里误用承气下之其死也必矣(脉在丙者脉浮也脉在丁者脉沉也脉
丙丁俱在有热者浮沉俱有力也)
余云衢太史形气充壮饮啖无人辛卯夏六月患热病肢体不甚热而间扬掷手足如躁扰状昏愦不知人事时发一二语不可
了而非谵也脉微细如欲绝有谓是阴证宜温者有谓当下者时座师陆葵曰先生与曾植斋冯琢庵二太史皆取决于余余谓是阳
病见阴脉在法为不治然素禀如此又值酷暑外烁酒灸内炎宜狂热如焚脉洪数有力而此何为者岂热气怫郁不得伸而然耶且
不大便七日矣姑以大柴胡汤下之时大黄止用二钱又熟煎而太医王雷庵力争以为太少不若用大承气余曰如此脉证岂宜峻
下待大柴胡不应而后用调胃承气调胃承气不应而后用小承气以及大承气未晚也已服药大便即行脉已出手足温矣余谓雷
庵曰设用大承气能免噬脐之悔哉继以黄连解毒汤数服而平七月初遂与陆先生同典试南京不复发矣明年余请告归里偶得
刘河间伤寒直格读之中有云蓄热内甚脉须疾数以其极热蓄甚而脉道不利反致脉沉细而欲绝俗未明造化之理反谓传为寒
极阴毒者或始得之阳热暴甚而便有此证候者或两感热甚者通宜解毒加大承气下之下后热稍退而未愈者黄连解毒汤调之
或微热未除者凉膈散调之或失下热极以至身冷脉微而昏冒将死若急下之则残阴暴绝而死盖阳气后竭而然也不下亦死宜
凉膈散或黄连解毒汤养阴退阳积热渐以宣散则心胸再暖而脉渐以生然后抚卷而叹曰古人先得我心矣余太史所患正失下
热极以至身冷脉微而昏冒欲绝者也下与不下大下与微下死生在呼吸间不容发呜乎可不慎哉因表而出之以为世鉴
(昏愦:旧版医书将“叉手冒心”的症状错误地归入此类,现已剔除。)
成无己注:郁是指气机郁结而不得舒展;冒是指神志昏蒙而不清晰,也就是俗称的昏迷。这些症状都是因为正气虚弱,寒气乘虚侵袭所致。《内经》说:“各种虚证遇到寒气侵袭就会发生厥逆、郁冒和肢体麻木不仁。”这是因为寒气乘人体虚弱而上侵头部。骆龙吉主张用附子汤,并倍加人参、川芎、天麻、干姜等药物来主治。又说:太阳病(太阳经受邪所致的病证)先用下法治疗未愈,接着又发汗,这样导致表里两虚。患者因此出现头目昏眩(冒)。患有郁冒的人,如果出汗则病自愈,因为这是表气调和的表现。如果不能出汗且病不解,用人参三白汤加入川芎、天麻;如果是下焦虚损、脉象微弱的,加附子以温补肾经,这是巩固根本的方法。《内经》说:“滋润苗株必须稳固其根本,砍伐树根会导致树梢枯萎”,说的就是这个道理。《金匮要略》说:刚生产后的妇女有三种病,一是痉病,二是郁冒,三是大便难。这是因为失血后又出汗,感受寒邪较多,导致郁冒。又说:产妇患郁冒,脉象微弱,不能进食,大便坚硬,这是由于血虚导致厥逆,厥逆必然导致昏冒。患有郁冒的人想要痊愈,必须出大汗。看这些情况,可知郁冒属于虚寒证。另外,少阴病(少阴经受邪所致的病证)下利停止后出现头晕目眩,时常感到昏蒙欲倒的,是死证,因为这是极度虚弱而阳气外脱的表现。
太阳病先使用下法而未愈,接着又发汗,因此导致表里俱虚。患者因此出现头目昏眩(冒)。患有郁冒的人,如果出汗则病自愈。之所以这样,是因为出汗后表气调和。如果里气尚未调和,然后再使用下法。
(成无己将“郁”解释为“冒”,我认为理解不够透彻。查《说文解字》,“冒”字由“曰”和“目”组成,“曰”即古代小孩及蛮夷戴的头巾。这里所说的“致冒”,意思是像物体遮蔽了眼睛一样,这是昏迷的意思。现在如果把“冒”解释为“郁”,不仅失去了六书造字的本义,也违背了病情及张仲景的原意。“里未和”三个字有时被误写,或者增加“未”字却不删除“得”字,这就违背了文理。现在依据宋本校正。)各种受寒气侵袭的病症,会出现厥逆、郁冒、肢体麻木不仁、口唇拘急不能说话、战栗发抖等症状。
太阳病与少阳病同时发病(并病),出现头项强痛,有时眩晕昏冒,有时感觉像结胸证那样心下部痞塞硬满的,应当针刺大椎穴、肺俞穴、肝俞穴。(关于项强的详细论述见相关章节)
阳明病(阳明经受邪所致的病证)患者小便不利,大便时而困难时而容易,偶尔有轻微发热,气喘且头目昏冒,不能平卧,这是因为体内有燥屎内结。适宜使用大承气汤。
少阴病表现为只想睡觉,下利停止后出现头晕目眩,时常感到昏蒙欲倒的,是死证。
厥阴病(厥阴经受邪所致的病证)下利排出未消化的食物,脉象沉迟,患者面部发红,身体有轻微发热,必然会出现郁冒出汗而后病解。(关于下利的详细论述见相关章节)
伤寒经过催吐或泻下治疗后,出现虚烦,脉象微弱。过了八九天,出现心下部痞塞硬满,胁下疼痛,气上冲咽喉,眩晕昏冒,经脉跳动惕动不安的,时间久了会发展成痿证。
海藏(张元素/李东垣学派医家)说:伤寒传变到五六天之间,逐渐变为神志昏迷、不语,或者在睡梦中独自说一两句梦话,眼睛发红,嘴唇焦裂,舌头干燥但不想喝水,给喝稀粥能咽下,不给就不想吃,六脉细数而不洪大,心下部没有痞块,腹部没有胀满,大小便正常。或者传变到十天左右,形貌像醉酒一样。医生见到神志昏迷不止,多用大承气汤攻下,这就错了。这是因为不知道此热邪传入手少阴心经。然而又不知道它从何经传来。回答是:原本太阳经伤风,风为阳邪,损伤卫气,阴血自然干燥,热邪结聚膀胱,病邪逆向传变于心(丙火)。丙丁如同兄妹,由此传入心经。心火从上向下逼迫熏蒸肺脏,所以导致神志昏迷。因为肺是清肃之脏,内有火邪,所以令神志昏迷。适宜使用栀子黄连黄芩汤。如果脉象显示病在丙(小肠/心包络层面,此处指代特定脉位或病机层次,通常浮为丙),用导赤散;脉象显示病在丁(心经层面,通常沉为丁),用泻心汤。如果误用凉膈散,那是气分中的血药。如果右手寸脉沉滑有力,则可以使用。或者使用犀角地黄汤,这也接近正确。原方所说如果没有犀角,可以用升麻代替,这是阳明经的药,是解除阳明经血中热邪的药物。如果脉象浮沉都有力,说明丙丁都有热,可以各半服用导赤散和泻心汤,这样就适宜了。这个证候是膀胱传丙,足经传手经,是下传上;丙传丁,是表传里;壬传丁,是艮卦传离卦。越经传变,又是腑传脏。《活人书》说伤寒只传足经不传手经,这话并不全面。也有从足经传到手的。怎么知道的呢?经文说伤寒有的只传一经,有的间传三经,不可拘泥于一种途径。只要观察脉象和外证来治疗,这才是灵活的方法。吃东西能咽下的,说明邪气不在胃;不想吃的,是因为神志昏迷的缘故。邪热既然不在里,误用承气汤攻下,死亡是必然的。(脉在丙者,指脉浮;脉在丁者,指脉沉;脉在丙丁俱有热者,指浮沉俱有力。)
余云衢太史,体质充壮,饮食旺盛。辛卯年夏六月,患热病,肢体不是很热,但间歇性地扬掷手足,像躁扰的样子,神志昏愦不知人事,偶尔说一两句话,语不成句,但不是谵语。脉象微细几乎要断绝。有人说这是阴证,宜用温法;有人说应该用下法。当时的座师陆葵说:“先生曾向曾植斋、冯琢庵两位太史请教,他们都取决于你。”我说这是阳病出现了阴脉,按法则是不治之症。但他素来体质如此,又正值酷暑,外受热邪灼烧,内有酒毒灸火炎症,理应高热如焚,脉象洪数有力,为什么却是这样呢?难道是热气怫郁不得伸展才这样的吗?而且已经七天不大便了。暂且用大柴胡汤攻下,其中大黄只用二钱,又熟煎。太医王雷庵极力争辩认为太少,不如用大承气汤。我说:“像这样的脉证,哪里适宜峻猛攻下?等待大柴胡汤无效后再用调胃承气汤,调胃承气汤无效后再用小承气汤以及大承气汤,也不晚。”服药后大便即行,脉象已出,手足温暖了。我对雷庵说:“假如用了大承气汤,能不后悔莫及吗?”随后服用几剂黄连解毒汤而病愈。七月初,我和陆先生一同主持南京的科举考试,病再未复发。第二年我告老还乡,偶然读到刘河间的《伤寒直格》,其中有云:“蓄积的热邪在内很严重,脉象必须疾数,因为极热蓄积甚多导致脉道不利,反而导致脉沉细而欲绝。”世俗之人不明白造化的道理,反而认为是传变为寒极阴毒。有的人刚开始阳热暴盛就出现这种证候,有的人两感热甚的,通宜解毒加大承气汤攻下。攻下后热势稍退但未痊愈的,用黄连解毒汤调理;或者微热未除的,用凉膈散调理;或者因失于攻下,热极以至于身冷脉微而昏冒将死的,如果急下,则残存的阴液会突然断绝而死,这是因为阳气后来竭尽导致的。不下也会死,适宜用凉膈散或黄连解毒汤养阴退阳,使积热逐渐宣散,然后心胸再次温暖,脉象逐渐恢复。于是抚卷感叹说:“古人早就说出了我的心声啊!”余太史所患的正是因失于攻下,热极以至于身冷脉微而昏冒欲绝的证候。下与不下,大下与微下,生死就在呼吸之间,不容发丝之差。唉,怎么能不谨慎呢!因此记录下来作为世人的借鉴。
(Confusion: Old medical texts erroneously included the symptom of "hands covering the heart" in this category, which has now been removed.)
Cheng Wuji's commentary: "Yu" (郁) refers to qi stagnation and inability to flow freely; "Mao" (冒) refers to mental confusion and lack of clarity, commonly known as coma. These conditions are caused by deficiency allowing cold pathogenic factors to invade. The *Neijing* states: "Various deficiency syndromes encountering cold will result in Jue (cold extremities), Mao (dizziness/confusion), and numbness." This is because cold pathogens invade upward when the body is weak. Luo Longji advocated treating this with Fuzi Tang (Aconite Decoction), doubling the dosage of Renshen (Ginseng), Chuanxiong (Sichuan Lovage Rhizome), Tianma (Gastrodia Rhizome), and Jiangtang (Dried Ginger). Furthermore, it is stated: In Taiyang disease (disease of the Taiyang channel), if purgation is used first without success, followed by sweating therapy, this leads to both exterior and interior deficiency. Consequently, the patient experiences Mao (dizziness/confusion). Patients with Mao who sweat will recover spontaneously, as this indicates the harmonization of the exterior. If sweating does not occur and the condition persists, Ren San Bai Tang (Three Whites Decoction with Ginseng) added with Chuanxiong and Tianma should be used; for those with lower jiao deficiency and a faint pulse, Fuzi (Aconite Root) is added to warm the Kidney channel, thereby consolidating the root. The *Neijing* says: "To nourish the shoots, one must solidify the roots; to chop the roots, the branches will wither." This principle applies here. The *Jingui Yaolue* states: Postpartum women suffer from three diseases: one is Jing (spasm), two is Mao (confusion), and three is difficult defecation. This is due to blood loss combined with sweating and excessive exposure to cold, leading to Mao. It also states: For postpartum Mao, the pulse is faint, there is an inability to eat, and hard stools, all resulting from blood deficiency causing Jue, which inevitably leads to Mao. Recovery from Mao requires profuse sweating. From this, we can understand that Mao belongs to deficiency-cold syndromes. Additionally, in Shaoyin disease (disease of the Shaoyin channel), if diarrhea stops but dizziness occurs and the patient frequently feels dizzy/faint, it is a death sign, indicating extreme deficiency and Yang collapse.
In Taiyang disease, if purgation is used first without success, followed by sweating, this leads to both exterior and interior deficiency. Consequently, the patient experiences Mao (dizziness/confusion). Patients with Mao who sweat will recover spontaneously. This is because sweating harmonizes the exterior. If the interior is not yet harmonized, then purgation may be used again.
(Cheng Wuji interpreted "Yu" as "Mao," which I believe is not sufficiently precise. According to *Shuowen Jiezi*, the character "Mao" consists of "Yue" (head covering) and "Mu" (eye). "Yue" refers to head coverings worn by children and barbarians. The "Mao" described here means something obscuring the eyes, implying coma. Interpreting "Mao" as "Yu" today not only loses the original etymological meaning but also contradicts the pathology and Zhang Zhongjing's intent. The phrase "Li Wei He" (Interior not harmonized) is sometimes corrupted; adding "Wei" without removing "De" violates textual logic. This is corrected according to the Song edition. Various conditions invaded by cold present with Jue (cold extremities), Mao (dizziness/confusion), numbness, oral rigidity/inability to speak, and shivering.)
When Taiyang and Shaoyang diseases occur simultaneously (Bing Bing), presenting with stiffness and pain in the head and neck, occasional dizziness and confusion, or sensations resembling Jie Xiong (chest binding) with hardness in the epigastrium, acupuncture at Dazhui (GV14), Feishu (BL13), and Ganshu (BL18) is indicated. (See relevant sections for details on neck stiffness.)
In Yangming disease (disease of the Yangming channel), patients exhibit difficulty urinating, alternating difficulty and ease in defecation, occasional slight fever, wheezing, dizziness/confusion, and inability to lie flat. This indicates dry stool accumulation. Da Chengqi Tang (Major Order the Qi Decoction) is appropriate.
Shaoyin disease presents with somnolence. If diarrhea stops but dizziness occurs and the patient frequently feels dizzy/faint, it is a death sign.
Jueyin disease (disease of the Jueyin channel) presents with diarrhea containing undigested food, a deep and slow pulse, facial redness, slight body heat, and inevitable Mao (confusion) with sweating before resolution. (See relevant sections for details on diarrhea.)
After vomiting or purgation in Shanghan (Cold Damage), restlessness and a faint pulse occur. After eight or nine days, epigastric fullness and hardness, hypochondriac pain, Qi rushing to the throat, dizziness/confusion, and twitching of meridians occur. Prolonged persistence leads to Wei syndrome (flaccidity).
Haizang (Zhang Yuansu/Li Dongyuan school physician) states: When Shanghan transmits to the fifth or sixth day, it gradually changes into unconsciousness and muteness, or speaking alone in sleep, red eyes, cracked lips, dry tongue without desire to drink, ability to swallow thin gruel if offered but refusal otherwise, fine and rapid pulses without fullness, no epigastric blockage, no abdominal distension, and normal urination/defecation. Or after ten days, the appearance resembles drunkenness. Physicians seeing persistent unconsciousness often use Da Chengqi Tang for purgation, which is an error. This is because they do not realize the heat has transmitted to the Hand-Shaoyin Heart channel. However, they fail to identify its origin. The answer is: Originally, Taiyang channel Wind-Strike. Wind is a Yang pathogen damaging Wei (Defensive) Qi, causing Yin Blood to dry. Heat accumulates in the Bladder, and the pathogen reversely transmits to Bing Fire (Small Intestine/Pericardium level). Bing and Ding are like siblings, thus transmitting to the Heart channel. Heart Fire presses down and steams the Lung, causing unconsciousness. Since the Lung is a pure and descending organ, internal fire causes unconsciousness. Zhi Zi Huang Lian Huang Qin Tang (Gardenia, Coptis, and Scutellaria Decoction) is suitable. If the pulse indicates Bing (floating), Dao Chi San (Guide Out Red Powder) is used; if Ding (deep), Xie Xin Tang (Drain the Epigastrium Decoction) is used. Misusing Liang Ge San (Cool the Terrace Powder), which acts on Qi-level blood, is incorrect. If the right Cun pulse is deep, slippery, and forceful, it may be used. Xi Jiao Di Huang Tang (Rhinoceros Horn and Rehmannia Decoction) is also close to correct. The original text suggests substitening Shengma (Cimicifuga) for Xi Jiao (Rhinoceros Horn), which is a Yangming channel herb for clearing blood-level heat. If floating and deep pulses are both forceful, indicating heat in both Bing and Ding, half doses of Dao Chi San and Xie Xin Tang taken together are appropriate. This syndrome involves Bladder transmitting to Bing, Foot channels transmitting to Hand channels (lower to upper); Bing to Ding (exterior to interior); Ren to Ding (Gen trigram to Li trigram). Transgressing channels involves Fu organs transmitting to Zang organs. *Huoren Shu* states Shanghan only transmits through Foot channels, not Hand channels; this statement is incomplete. Transmission from Foot to Hand channels does occur. How do we know? The classics state Shanghan may transmit to one channel or skip to three channels; it cannot be treated via a single route. Treatment depends on observing pulses and external signs—this is flexible practice. Swallowing food indicates the pathogen is not in the Stomach; refusal to eat is due to unconsciousness. Since the pathogenic heat is not in the interior, misusing Chengqi formulas for purgation will certainly lead to death. (Pulse in Bing refers to floating; Pulse in Ding refers to deep; Pulse in both Bing and Ding with heat refers to forceful floating and deep pulses.)
Yu Yunqu, a Grand Secretary, had a robust constitution and hearty appetite. In the summer of June in the Xinmao year, he suffered from a febrile disease. His limbs were not very hot, but he intermittently threw his limbs about in a restless manner, was confused and unaware of his surroundings, occasionally spoke incomprehensible words but not delirious speech. His pulse was faint and thin, nearly absent. Some argued it was a Yin syndrome requiring warming; others argued for purgation. My colleague Lu Kui said, "You previously advised Zeng Zhizhai and Feng Zhuo'an, both Grand Secretaries, and they deferred to you." I said, "This is a Yang syndrome presenting with Yin pulses, which is technically incurable." However, given his natural constitution and the intense summer heat externally scorching him, plus internal inflammation from alcohol and moxibustion, he should have had high fever and a full, rapid, forceful pulse. Why was it so? Was it due to constrained heat unable to extend? Moreover, he had not defecated for seven days. I tentatively used Da Chaihu Tang (Major Bupleurum Decoction) for purgation, using only two qian of Dahuang (Rhubarb), decocted thoroughly. Imperial Physician Wang Leian strongly argued this was insufficient and suggested Da Chengqi Tang instead. I replied, "With such pulses and symptoms, harsh purgation is inappropriate. Wait until Da Chaihu Tang fails, then use Tiao Wei Chengqi Tang (Regulate the Stomach Order the Qi Decoction); if that fails, then Xiao Chengqi Tang (Minor Order the Qi Decoction), and finally Da Chengqi Tang." After taking the medicine, defecation occurred, the pulse became palpable, and hands and feet warmed. I told Leian, "Had we used Da Chengqi Tang, would we not regret it later?" Subsequently, several doses of Huanglian Jiedu Tang (Coptis Decoction to Resolve Toxicity) cured him. In early July, Lu and I went to Nanjing to supervise examinations, and the illness did not recur. The following year, upon retiring, I read Liu Hejian's *Shanghan Zhige*. It states: "Severe internal heat accumulation requires rapid pulses; extreme heat obstructs pulse vessels, paradoxically causing deep, faint, nearly absent pulses." Laypeople misunderstand this mechanism, mistaking it for extreme cold/Yin toxicity. Some present with sudden severe Yang heat initially; some with simultaneous severe heat transmission should generally receive detoxification plus Da Chengqi Tang. If heat subsides slightly but persists after purgation, Huanglian Jiedu Tang regulates it; if slight heat remains, Liang Ge San regulates it. If failure to purge leads to extreme heat, cold body, faint pulse, and impending coma/death, urgent purgation causes sudden destruction of residual Yin due to exhausted Yang. Not purging also leads to death. One should use Liang Ge San or Huanglian Jiedu Tang to nourish Yin, retreat Yang, and gradually dissipate accumulated heat, restoring warmth to the chest and pulse generation. Sighing at the book, I thought, "The ancients anticipated my thoughts!" Yu Taishi's condition was exactly that of extreme heat from delayed purgation, leading to cold body, faint pulse, and coma. Life and death hung in the balance between purging and not purging, severely or mildly. Alas, how careful one must be! I record this as a warning for the world.