人身血气，昼行阳，夜行阴，自平旦寅时，从中焦注手太阴肺经；卯时，注手阳明
大肠经；辰时，注足阳明胃经；巳时，注足太阴脾经；午时，注手少阴心经；未时，注
手太阳小肠经；申时，注足太阳膀胱经；酉时，注足少阴肾经；戌时，注手厥阴心胞
经；亥时，注手少阳三焦经；子时，注足少阳胆经；丑时，注足厥阴肝经。气血循行，
不可太过，不可不及，候气失时，灾HT 立见。且人之手足，各有三阴三阳。手之三
阴，从脏走至手，手之三阳，从手走至头，足之三阳，从头下走至足，足之三阴，从足
上走入腹，共合十二经络。更有曰∶凡子午卯酉日阴交于阳，气不足，其痘多攻，寅申
巳亥日，阳会于阴，血不足，其痘多剥，辰日阳气行下，血留不进，其痘补血。戌日阴
气行上，气留不足，其痘补气，丑未日气血均行，其痘多吉，此以时日阴阳立说也。然
人身气血虚实，一览可知，且性禀阴阳各异，岂可拘一定之时候，以概不一之性禀哉！
一日二日，胎毒自肾而发，至骨髓之分。二日三日传心血脉之分。三日四传脾胃
肌肉之分。四日五日，传至肝筋之分。五日六日，传肺皮毛之表。七日八日浓浓渐干而
愈。否则，为倒靥，或成痈肿矣。
肝为水泡，其色青小，是即俗谓水痘也。肺为脓泡，稠浊色白而大，是即俗谓痘
子也。心为斑而主血，其色赤而小，次于水泡，是即俗谓喑子也。脾为疹，其色浅黄，
而次必斑，是即俗谓麻子也。
人体的气血，白天运行于阳经，夜晚运行于阴经。从清晨寅时开始，气血从中焦注入手太阴肺经（主管呼吸和气血运行的经脉）；卯时，注入手阳明大肠经（与肺相表里的经脉）；辰时，注入足阳明胃经（多气多血的经脉）；巳时，注入足太阴脾经（主运化的经脉）；午时，注入手少阴心经（主宰血脉的经脉）；未时，注入手太阳小肠经（受盛之官）；申时，注入足太阳膀胱经（主一身之表）；酉时，注入足少阴肾经（先天之本）；戌时，注入手厥阴心包经（代心行令的经脉）；亥时，注入手少阳三焦经（决渎之官，水道出焉）；子时，注入足少阳胆经（中正之官）；丑时，注入足厥阴肝经（主疏泄和藏血）。气血的循行，不能太过分，也不能不及，如果候气的时机失去平衡，灾祸立刻就会显现。
而且人的手足，各有三条阴经和三条阳经。手的三条阴经，从内脏走向手部；手的三条阳经，从手部走向头部；足的三条阳经，从头部向下走向足部；足的三条阴经，从足部向上走入腹部，合起来共十二条经络。
另有说法认为：凡是逢子、午、卯、酉的日子，阴气交于阳气，气不足，痘疮容易攻陷；逢寅、申、巳、亥的日子，阳气会合于阴气，血不足，痘疮容易脱落；逢辰日，阳气下行，血液停留而不进，痘疮需要补血；逢戌日，阴气上行，气停留而不足，痘疮需要补气；逢丑、未日，气血均能正常运行，痘疮大多吉利。这是根据时日阴阳来立论的说法。然而，人身气血的虚实，一眼就可以知道，况且每个人的禀赋阴阳各不相同，怎么能拘泥于固定的时辰，来概括不一的个体禀赋呢！
第一天第二天，胎毒从肾脏发出，到达骨髓的层次。第二天第三天，传变到心脏和血脉的层次。第三天第四天，传变到脾胃和肌肉的层次。第四天第五天，传变到肝脏和筋膜的层次。第五天第六天，传变到肺脏和皮毛的表面。第七天第八天，痘疹浓稠逐渐干燥而痊愈。否则，就会变成倒靥（痘疮内陷），或者形成痈肿。
肝脏对应水泡，颜色青小，这就是俗称的水痘。肺脏对应脓泡，稠浊色白且大，这就是俗称的痘子（天花）。心脏对应斑，主司血液，颜色赤红且小，次于水泡，这就是俗称的喑子（麻疹的一种或重症痘）。脾脏对应疹，颜色浅黄，其次必有斑，这就是俗称的麻子（麻疹）。
Human Qi and Blood circulate in the Yang meridians during the day and in the Yin meridians at night. Starting from the Yin hour (03:00-05:00) at dawn, Qi and Blood flow from the Middle Jiao into the Lung Meridian of Hand-Taiyin; at the Mao hour (05:00-07:00), they flow into the Large Intestine Meridian of Hand-Yangming; at the Chen hour (07:00-09:00), into the Stomach Meridian of Foot-Yangming; at the Si hour (09:00-11:00), into the Spleen Meridian of Foot-Taiyin; at the Wu hour (11:00-13:00), into the Heart Meridian of Hand-Shaoyin; at the Wei hour (13:00-15:00), into the Small Intestine Meridian of Hand-Taiyang; at the Shen hour (15:00-17:00), into the Bladder Meridian of Foot-Taiyang; at the You hour (17:00-19:00), into the Kidney Meridian of Foot-Shaoyin; at the Xu hour (19:00-21:00), into the Pericardium Meridian of Hand-Jueyin; at the Hai hour (21:00-23:00), into the Sanjiao Meridian of Hand-Shaoyang; at the Zi hour (23:00-01:00), into the Gallbladder Meridian of Foot-Shaoyang; and at the Chou hour (01:00-03:00), into the Liver Meridian of Foot-Jueyin. The circulation of Qi and Blood should be neither excessive nor insufficient. If the timing of Qi is missed or imbalanced, disaster will appear immediately.
Furthermore, each hand and foot has three Yin and three Yang meridians. The three Yin meridians of the hands travel from the Zang organs to the hands; the three Yang meridians of the hands travel from the hands to the head; the three Yang meridians of the feet travel from the head down to the feet; and the three Yin meridians of the feet travel from the feet up into the abdomen, totaling twelve meridians.
There is another theory: On days corresponding to Zi, Wu, Mao, and You, Yin intersects with Yang, leading to a deficiency of Qi, causing variola (smallpox) lesions to tend to collapse (Dao Ye). On days corresponding to Yin, Shen, Si, and Hai, Yang converges with Yin, leading to a deficiency of Blood, causing variola lesions to tend to slough off. On Chen days, Yang Qi moves downward, while Blood stagnates and does not advance, requiring blood tonification for the lesions. On Xu days, Yin Qi moves upward, while Qi stagnates and becomes deficient, requiring Qi tonification for the lesions. On Chou and Wei days, both Qi and Blood circulate evenly, indicating a generally auspicious prognosis for the lesions. This theory is established based on the Yin and Yang of time and days. However, the deficiency and excess of human Qi and Blood can be known at a glance. Moreover, since individual constitutional Yin and Yang vary, how can one rigidly adhere to fixed times to generalize over diverse constitutions?
On the first and second days, fetal toxin emerges from the Kidneys, reaching the level of the bone marrow. On the second and third days, it transmits to the level of the Heart and blood vessels. On the third and fourth days, it transmits to the level of the Spleen, Stomach, and muscles. On the fourth and fifth days, it transmits to the level of the Liver and sinews. On the fifth and sixth days, it transmits to the exterior level of the Lungs and skin/hair. By the seventh and eighth days, the lesions become thickened and gradually dry out, leading to recovery. Otherwise, it may result in Dao Ye (inverted lesions) or form carbuncles and swellings.
The Liver corresponds to water blisters, which are greenish and small; this is commonly known as chickenpox (Shui Dou). The Lungs correspond to purulent blisters, which are turbid, white, and large; this is commonly known as variola (Dou Zi). The Heart corresponds to macules, governing blood, which are reddish and small, secondary to water blisters; this is commonly known as An Zi. The Spleen corresponds to papules/rash, which are pale yellow, followed by macules; this is commonly known as measles (Ma Zi).