【方歌】杨梅疮生有二般，精化气化是其源，精化淫欲气传染，
气宜发汗精下痊。
【注】此证一名广疮，因其毒出自岭南；一名时疮，以时气乖
变，邪气凑袭之故；一名棉花疮，因其缠绵不已也；一
名翻花杨梅，因窠粒破烂，肉反突于外，如黄蜡色；一
名天泡疮，因其夹湿而生白疱也。有形如赤豆，嵌于肉
内，坚硬如针，名杨梅痘；有形如风疹作痒，名杨梅疹
；先起红晕，后发斑点者，名杨梅斑；色红作痒，其圈
大小不一，二三相套，因食秽毒之物，入大肠而发，名
杨梅圈。其名形虽异，总不出气化、精化二因。但气化
传染者轻，精化欲染者重。气化者，或遇生此疮之人，
鼻闻其气，或误食不洁之物，或登圊受梅毒不洁之气，
脾、肺受毒，故先从上部见之，皮肤作痒，筋骨微疼，
其形小而且干也。精化者，由交媾不洁，精泄时，毒气
乘肝、肾之虚而入于里，此为欲染，先从下部见之，筋
骨多痛，或小水涩淋，疮形大而且坚。气化者毒在表，
未经入里，稍有萌动，宜急服透骨搜风散；元气实者，
杨梅一剂散汗之。精化者毒在里，深伏骨髓，未透肌肤
，宜服九龙丹，通利大、小二便，以泻骨中之毒，甚者
二服，降下毒物，以土深压之。行泻之后，体实者，升
麻解毒汤；体虚者，归灵内托散，服至筋骨不疼，疮色
淡白，内毒已解，再用金蟾脱壳酒一料扫余毒，以绝其
源。
如梅毒初发，服表药时，恐上攻头面，宜豫服护面散；
或疮势已发于面，愈后斑痕不退，宜翠云散点之，以灭
痕迹。若梅疮溃烂时，脓秽浸淫成片而痛者，以鹅黄散
撒之。又翻花杨梅，亦以本方加雄黄末，香油调敷之。
外有护从丸，于发疮时，令侍从人服之，可免传染。梅
疮初起，头不痛，筋骨不疼，小水通利，疮形碎小色鲜
，头面稀少，口角无疮，胸背稠密，谷道清楚者为顺；
若先发下疳，次生便毒、鱼口，便觉筋骨疼痛，而梅疮
随发，色紫坚硬，手足多生，形如汤泼起疱者为险。总
之始终调治得法，轻者半年，重者一载，始得全愈。若
患者不遵正法医治，欲求速效，强服轻粉、水银、白粉
霜劫药等类，妄用熏、擦、哈、吸等法，以致毒含藏骨
髓，复为倒发结毒，轻则累及妻子，甚则腐烂损形，不
可不慎。
方剂：透骨搜风散＇
组成：透骨草（白花者，阴干） 生脂麻
羌活 独活
小黑豆 紫葡萄
槐子 白糖
六安茶 核桃肉（各一钱五分）
生姜三片，红枣肉三枚，水三钟，煎一钟；露一宿
，空心热服，盖被出汗，避风。
【方歌】透骨搜风散梅毒，筋骨微疼痒皮肤，脂麻羌独豆葡萄，
槐子糖茶核桃肉。
又方：杨梅一剂散
组成：麻黄（蜜炙，一两） 威灵仙（八钱）
大黄（七钱） 羌活
白芷 皂刺
金银花 穿山甲（炙，研）
蝉蜕（各五钱） 防风（三钱）
山羊肉一斤，河水煮熟，取清汤二碗，用黄酒一碗
，将药煎至一碗，令患者空心将羊肉淡食令饱，随后服
药，盖被出汗，避风。
【方歌】杨梅一剂元气壮，上部生毒气化疮，麻黄羌芷威灵刺，
银花风甲蝉大黄。
又方：升麻解毒汤
组成：升麻 皂刺（各四钱）
土茯苓（一斤）
水八碗，煎四碗，作四次，一日服尽。每次炖热，
加香油三茶匙和匀，量病上、下，食前后服之。
如疮生顶上加白芷。咽内加桔梗，胸腹加白芍，肩
背加羌活，下部加牛膝。
【方歌】升麻解毒筋骨疼，梅毒缠绵壮服灵，土苓皂刺香油服，
按部须加药引经。
又方：归灵内托散
组成：人参 木瓜
白术（土炒） 金银花
防己 天花粉
白鲜皮 薏苡仁（各一钱）
当归 熟地
白芍（酒炒） 川芎（各一钱）
土茯苓（二两） 威灵仙（六分）
甘草（五分）
水三钟，煎二钟，作二次，随病上下服之，渣再煎
服。
下部加牛膝五分，元气虚者倍加参、归，毒气盛者
倍金银花，加蒲公英。
外以麦冬五钱（去心），薏苡仁五钱，土茯苓一两
，煎汤常服以代茶。
【方歌】归灵内托参木瓜，术银四物己天花，土苓鲜薏威灵草，
梅疮体弱服堪夸。
又方：金蝉脱壳酒
组成：醇酒五斤，大虾蟆一个，土茯苓五两浸酒内，瓶口封严
，重汤煮二炷香时取出。待次日饮之，以醉为度。无论
冬夏，盖暖出汗为效。余存之酒，次日随量饮之，酒尽
疮愈。又治结毒筋骨疼痛，诸药不效者更妙。服酒七日
后，禁见风为效，忌口及房欲。
又方：护面散
组成：女人头发（〔火段〕，存性）明雄黄（各三分）
共研细，香油半酒钟调匀，滚黄酒冲服，一日三服
。
【方歌】护面散医梅疮现，豫服毒不攻头面，香油调药黄酒冲，
只用雄黄头发〔火段〕。
又方：翠云散
组成：轻粉（一两） 石膏（〔火段〕，一两）
蟾矾 铜绿（各五钱）
共研极细末，湿疮干撒，干疮以公猪胆汁调浓点之
每日三次，斑疮自退。
【方歌】翠云散去疮后斑，轻粉石膏共胆矾，铜绿共研湿干撒，
猪胆汁调能润干。
又方：鹅黄散
组成：轻粉 石膏（〔火段〕）
黄柏（炒，各等分）
共为末，干撒患处，即可生痂；再烂再撒，毒尽即
愈。
【方歌】鹅黄散治梅疮烂，脓秽多疼浸成片，轻粉石膏黄柏研，
干撒止疼解毒验。
又方：护从丸
组成：雄黄 川椒（各五钱）
杏仁（炒，去皮、尖）
共研末，烧酒打飞罗面糊为丸，如梧桐子大。每服
十五丸，白滚水送下。
【方歌】护从丸避梅疮患，雄黄川椒各五钱，杏仁百粒酒糊入，
从人服之毒不传。
又方：九龙丹（见下部悬痈）
【方歌】杨梅疮的发生主要有两种类型，精气化生和气机传染是其根源。精气化生的多因淫欲过度，气机传染的则通过空气传播；对于气机传染型的宜采用发汗法治疗，精气化生的宜采用攻下法治疗。
【注】此病又名广疮，因为毒邪出自岭南地区；又名时疮，因为时令气候乖变，邪气乘虚侵袭所致；又名棉花疮，因为其病情缠绵难愈；又名翻花杨梅，因为疮窠颗粒破烂，肌肉反突于外部，呈黄蜡色；又名天泡疮，因为夹杂湿气而生白疱。形态像赤豆，嵌入肉内，坚硬如针，称为杨梅痘；形态像风疹且瘙痒，称为杨梅疹；先出现红晕，后发出斑点的，称为杨梅斑；颜色红且瘙痒，圆圈大小不一，两三个套叠在一起，因为食用了秽毒之物，毒入大肠而发作，称为杨梅圈。虽然名称和形态各异，但总不出气化和精化这两种病因。但是气机传染者病情较轻，精气欲染者病情较重。气机传染型，或者是遇到患有此疮的人，鼻子闻到其气味，或者误食不洁之物，或者上厕所受到梅毒不洁之气的侵袭，脾、肺受毒，所以先从上部显现，皮肤瘙痒，筋骨轻微疼痛，疮形小而且干燥。精气化生型，由性交不洁，射精时，毒气趁肝、肾虚弱而入里，这属于欲染，先从下部显现，筋骨多疼痛，或者小便涩滞淋沥，疮形大而且坚硬。气机传染型毒在体表，未进入体内，稍有萌动迹象，宜急服透骨搜风散；元气充实者，用杨梅一剂散发汗。精气化生型毒在体内，深伏骨髓，未透达肌肤，宜服用九龙丹，通利大、小便，以泻出骨中之毒，严重的服两次，降下毒物，以土性药物压制它。行泻之后，体质强者，用升麻解毒汤；体质弱者，用归灵内托散，服用至筋骨不疼，疮色淡白，内毒已解，再用金蟾脱壳酒一料清除余毒，以绝其根源。
如果梅毒初发，服用解表药时，担心毒气上攻头面，宜预先服用护面散；或者疮势已经发于面部，痊愈后面部斑痕不退，宜用翠云散点涂，以消除痕迹。若梅疮溃烂时，脓液秽物浸淫成片且疼痛的，用鹅黄散撒敷。又有翻花杨梅，也用本方加雄黄末，香油调匀外敷。外用有护从丸，在发病时，让侍从人员服用，可避免传染。梅疮初起，头部不痛，筋骨不疼，小便通利，疮形碎小颜色鲜艳，头面稀少，口角无疮，胸背稠密，肛门部位清楚者为顺证；如果先发下疳，接着生便毒、鱼口，便觉得筋骨疼痛，而梅疮随之发作，颜色紫暗坚硬，手足多处生长，形状像被热水烫起泡的为险证。总之始终调理治疗得当，轻者半年，重者一年，才能完全痊愈。如果患者不遵循正确方法医治，想求速效，强行服用轻粉、水银、白粉霜等劫毒药类，妄用熏、擦、哈、吸等方法，导致毒邪含藏于骨髓，再次复发为结毒，轻则连累妻子，重则腐烂损形，不可不慎。
方剂：透骨搜风散
组成：透骨草（白花者，阴干） 生脂麻
羌活 独活
小黑豆 紫葡萄
槐子 白糖
六安茶 核桃肉（各一钱五分）
生姜三片，红枣肉三枚，水三钟，煎取一钟；露置一夜，空腹热服，盖被出汗，避风。
【方歌】透骨搜风散治梅毒，筋骨微疼皮肤痒，脂麻羌活独活黑豆葡萄，槐子糖茶核桃肉。
又方：杨梅一剂散
组成：麻黄（蜜炙，一两） 威灵仙（八钱）
大黄（七钱） 羌活
白芷 皂刺
金银花 穿山甲（炙，研）
蝉蜕（各五钱） 防风（三钱）
山羊肉一斤，河水煮熟，取清汤二碗，用黄酒一碗，将药煎至一碗，令患者空腹将羊肉清淡食用至饱，随后服药，盖被出汗，避风。
【方歌】杨梅一剂元气壮，上部生毒气化疮，麻黄羌活白芷威灵仙皂刺，银花防风穿山甲蝉蜕大黄。
又方：升麻解毒汤
组成：升麻 皂刺（各四钱）
土茯苓（一斤）
水八碗，煎至四碗，分四次，一日服尽。每次炖热，加香油三茶匙和匀，根据病位在上或在下，饭前或饭后服用。
如果疮生在头顶加白芷。咽内加桔梗，胸腹加白芍，肩背加羌活，下部加牛膝。
【方歌】升麻解毒治筋骨疼，梅毒缠绵体壮服灵，土茯苓皂刺香油服，按部位须加引经药。
又方：归灵内托散
组成：人参 木瓜
白术（土炒） 金银花
防己 天花粉
白鲜皮 薏苡仁（各一钱）
当归 熟地
白芍（酒炒） 川芎（各一钱）
土茯苓（二两） 威灵仙（六分）
甘草（五分）
水三钟，煎取二钟，分二次，根据病位上下服用，药渣再煎服。
下部加牛膝五分，元气虚者加倍加入参、当归，毒气盛者加倍金银花，加蒲公英。
外用麦冬五钱（去心），薏苡仁五钱，土茯苓一两，煎汤常服以代茶。
【方歌】归灵内托散用人参木瓜，白术金银花四物汤防己天花粉，土茯苓白鲜皮薏苡仁威灵仙甘草，梅疮体弱者服用值得夸耀。
又方：金蟾脱壳酒
组成：醇酒五斤，大虾蟆一个，土茯苓五两浸酒内，瓶口封严，隔水加热煮两炷香时间取出。待次日饮用，以喝醉为限度。无论冬夏，盖暖出汗为有效。剩余的酒，次日随量饮用，酒尽疮愈。又治结毒引起的筋骨疼痛，其他药物无效的更妙。服酒后七日内，禁止见风为有效，忌口及房事。
又方：护面散
组成：女人头发（烧炭存性）明雄黄（各三分）
共研细，香油半酒钟调匀，滚黄酒冲服，一日三次。
【方歌】护面散医梅疮现，预防毒气攻头面，香油调药黄酒冲，只用雄黄头发烧炭。
又方：翠云散
组成：轻粉（一两） 石膏（烧，一两）
蟾矾 铜绿（各五钱）
共研极细末，湿疮干撒，干疮以公猪胆汁调浓点涂，每日三次，斑疮自退。
【方歌】翠云散去疮后斑，轻粉石膏共胆矾，铜绿共研湿疮干撒，猪胆汁调能润干疮。
又方：鹅黄散
组成：轻粉 石膏（烧）
黄柏（炒，各等分）
共为末，干撒患处，即可生痂；再烂再撒，毒尽即愈。
【方歌】鹅黄散治梅疮烂，脓秽多疼浸成片，轻粉石膏黄柏研，干撒止疼解毒验。
又方：护从丸
组成：雄黄 川椒（各五钱）
杏仁（炒，去皮、尖）
共研末，烧酒打飞罗面糊为丸，如梧桐子大。每服十五丸，白开水送下。
【方歌】护从丸避梅疮患，雄黄川椒各五钱，杏仁百粒酒糊入，随从人员服之毒不传。
又方：九龙丹（见下部悬痈章节）
[Prescription Verse] Chancre (Chancre) arises in two types; essence transformation and qi transmission are their sources. Essence transformation stems from lust, while qi transmission is contagious. For qi transmission, sweating therapy is indicated; for essence transformation, purgation is indicated.
[Annotation] This condition is also known as Guang Chuang (Broad Chancre), because the toxin originates from the Lingnan region; it is also called Shi Chuang (Seasonal Chancre), due to abnormal seasonal climate changes allowing pathogenic factors to invade; it is named Mian Hua Chuang (Cotton Chancre) because of its lingering and persistent nature; it is called Fan Hua Yang Mei (Reversed Flower Myrtle Berry) because the craterous granules break open, with flesh protruding outward like yellow wax; it is named Tian Pao Chuang (Heaven Blister Chancre) because it involves dampness generating white blisters. Those resembling red beans, embedded in the flesh and hard as needles, are called Yang Mei Dou (Myrtle Berry Pox); those resembling wind rash with itching are called Yang Mei Zhen (Myrtle Berry Rash); those starting with a red halo and later developing spots are called Yang Mei Ban (Myrtle Berry Spots); those that are red, itchy, with circles of varying sizes, two or three concentric rings, caused by consuming toxic substances entering the large intestine, are called Yang Mei Quan (Myrtle Berry Rings). Although names and forms differ, they all stem from either qi transformation or essence transformation. However, qi transmission cases are mild, while essence contamination cases are severe. In qi transmission cases, one may inhale the odor of an infected person, ingest unclean food, or be exposed to toxic vapors in latrines. The Spleen and Lung receive the toxin, so symptoms appear first on the upper body: skin itching and slight bone/joint pain, with small, dry lesions. In essence transformation cases, caused by impure sexual intercourse, when semen is discharged, toxins enter the interior taking advantage of Liver and Kidney deficiency. This is "desire contamination," appearing first on the lower body: frequent bone/joint pain, difficult or painful urination, with large, hard lesions. Qi transmission toxins remain on the exterior, not yet penetrating the interior; if just beginning to manifest, urgently administer Tou Gu Sou Feng San (Bone-Penetrating Wind-Searching Powder). If Yuan Qi (Primal Qi) is robust, use Yang Mei Yi Ji San (Myrtle Berry One-Dose Powder) to induce sweating. Essence transformation toxins reside in the interior, deeply hidden in the marrow, not yet reaching the skin; administer Jiu Long Dan (Nine Dragons Pill) to promote bowel and urinary movement, draining toxins from the bones. Severe cases may require two doses to purge toxic matter, using earth-natured herbs to suppress them. After purgation, if the constitution is strong, use Sheng Ma Jie Du Tang (Cimicifuga Detoxification Decoction); if weak, use Gui Ling Nei Tuo San (Gui Ling Internal-Supporting Powder). Continue until bone/joint pain ceases, lesions turn pale white, and internal toxins are resolved. Then, use Jin Chan Tuo Qiao Jiu (Golden Cicada Molting Wine) to clear residual toxins and cut off the source.
If Syphilis (Mei Chuang) is in its initial stage and taking exterior-releasing medicines, fear of toxins attacking the head and face warrants pre-administration of Hu Mian San (Face-Protection Powder). If lesions have already appeared on the face and scars remain after healing, apply Cui Yun San (Emerald Cloud Powder) to fade marks. If chancre ulcerates with pus and filth spreading over a large area causing pain, sprinkle E Huang San (Goose Yellow Powder). For Fan Hua Yang Mei, add Realgar powder to this formula, mixed with sesame oil for external application. There is also Hu Cong Wan (Attendant-Protecting Pill); having attendants take it during outbreaks prevents transmission. Initial Chancre presenting without headache, bone/joint pain, or urinary difficulty, with small, bright red lesions sparse on the head/face but dense on chest/back, and clear anal region, indicates a favorable prognosis (Shun). If Chancre follows the appearance of Chancre Ulcer (Xia Gan) and Buboes (Bian Du/Yu Kou), accompanied by bone/joint pain, dark purple hard lesions, widespread on hands/feet, resembling scald blisters, indicates a dangerous prognosis (Xian). Ultimately, with proper treatment throughout, mild cases resolve in half a year, severe cases in one year. If patients do not follow correct methods, seeking quick results by forcibly taking corrosive drugs like Calomel (Qing Fen), Mercury (Shui Yin), or White Frost (Bai Fen Shuang), or abusing fumigation, rubbing, inhalation methods, toxins hide in the marrow, leading to recurrent Condyloma (Dao Fa Jie Du). Mildly, it affects spouses; severely, it causes rotting and deformity. Caution is essential.
Formula: Tou Gu Sou Feng San (Bone-Penetrating Wind-Searching Powder)
Composition: Tou Gu Cao (Daphne Genkwa, white-flowered variety, dried in shade), Sesame Seed (Sheng Zhi Ma), Notopterygium Root (Qiang Huo), Angelica Pubescens Root (Du Huo), Black Soybean (Xiao Hei Dou), Purple Grape (Zi Pu Tao), Sophora Fruit (Huai Zi), White Sugar (Bai Tang), Lu'an Tea (Liu An Cha), Walnut Meat (Tao He Rou) (each 1.5 qian).
Ginger (3 slices), Red Date Flesh (3 pieces), Water (3 zhong), decoct to obtain 1 zhong. Expose overnight, drink hot on an empty stomach, cover with blankets to induce sweating, avoid wind.
[Verse] Tou Gu Sou Feng San treats Syphilis, slight bone/joint pain and skin itching; Sesame, Notopterygium, Angelica, Black Bean, Grape, Sophora, Sugar, Tea, Walnut.
Another Formula: Yang Mei Yi Ji San (Myrtle Berry One-Dose Powder)
Composition: Ephedra Stem (Ma Huang, honey-fried, 1 liang), Spirit Vine Stem (Wei Ling Xian, 8 qian), Rhubarb Root (Da Huang, 7 qian), Notopterygium Root (Qiang Huo), Angelica Dahurica Root (Bai Zhi), Gleditsia Sinensis Thorn (Zao Ci), Chrysanthemum Indicum Flower (Jin Yin Hua), Pangolin Scale (Chuan Shan Jia, fried, ground), Silkworm Moth Cocoon (Chan Tui, each 5 qian), Saposhnikovia Root (Fang Feng, 3 qian).
Mountain Goat Meat (1 jin), boiled in river water, take 2 bowls of clear broth. Add 1 bowl of Yellow Wine, decoct herbs to 1 bowl. Patient eats goat meat plainly until full on an empty stomach, then takes medicine, covers blankets to sweat, avoids wind.
[Verse] Yang Mei Yi Ji San strengthens Yuan Qi, for upper body toxins from qi transmission; Ephedra, Notopterygium, Angelica, Spirit Vine, Thorn, Chrysanthemum, Saposhnikovia, Pangolin, Silkworm, Rhubarb.
Another Formula: Sheng Ma Jie Du Tang (Cimicifuga Detoxification Decoction)
Composition: Cimicifuga Rhizome (Sheng Ma), Gleditsia Sinensis Thorn (Zao Ci) (each 4 qian), Smilax Glabra Rhizome (Tu Fu Ling, 1 jin).
Water (8 bowls), decoct to 4 bowls, divide into 4 doses, consume within one day. Heat each dose, mix with 3 teaspoons of Sesame Oil. Take before or after meals depending on lesion location (upper/lower).
Add Bai Zhi if lesions are on the vertex. Add Platycodon Root (Jie Geng) for throat involvement. Add White Peony Root (Bai Shao) for chest/abdomen. Add Notopterygium Root (Qiang Huo) for shoulders/back. Add Achyranthes Root (Niu Xi) for lower body.
[Verse] Sheng Ma Jie Du Tang relieves bone/joint pain, for lingering Syphilis in robust constitutions; Tu Fu Ling, Zao Ci, Sesame Oil; add meridian-guiding herbs by location.
Another Formula: Gui Ling Nei Tuo San (Gui Ling Internal-Supporting Powder)
Composition: Ginseng Root (Ren Shen), Papaya (Mu Gua), Atractylodes Macrocephala Rhizome (Bai Zhu, soil-fried), Chrysanthemum Indicum Flower (Jin Yin Hua), Pyracantha Root (Fang Ji), Trichosanthes Root (Tian Hua Fen), Dictamnus Bark (Bai Xian Pi), Coix Seed (Yi Yi Ren) (each 1 qian), Angelica Sinensis Root (Dang Gui), Rehmannia Root (Shu Di), White Peony Root (Bai Shao, wine-fried), Szechwan Lovage Root (Chuan Xiong) (each 1 qian), Smilax Glabra Rhizome (Tu Fu Ling, 2 liang), Spirit Vine Stem (Wei Ling Xian, 6 fen), Licorice Root (Gan Cao, 5 fen).
Water (3 zhong), decoct to 2 zhong, divide into 2 doses, take according to lesion location. Decoct dregs again for second use.
Add Niu Xi (5 fen) for lower body. Double Ren Shen and Dang Gui for deficient Yuan Qi. Double Jin Yin Hua and add Dandelion (Pu Gong Ying) for intense toxins.
Externally: Ophiopogon Root (Mai Dong, heart removed, 5 qian), Coix Seed (Yi Yi Ren, 5 qian), Smilax Glabra Rhizome (Tu Fu Ling, 1 liang), decoct and drink regularly as tea.
[Verse] Gui Ling Nei Tuo San uses Ren Shen, Mu Gua, Bai Zhu, Jin Yin Si Wu Tang, Fang Ji, Tian Hua Fen, Tu Fu Ling, Bai Xian Pi, Yi Yi Ren, Wei Ling Xian, Gan Cao; praised for weak constitutions with Chancre.
Another Formula: Jin Chan Tuo Qiao Jiu (Golden Cicada Molting Wine)
Composition: Strong Wine (5 jin), Large Toad (1), Smilax Glabra Rhizome (Tu Fu Ling, 5 liang) soaked in wine. Seal bottle tightly, heat in water bath for duration of two incense sticks, then remove. Drink next day, up to intoxication. Regardless of season, warmth and sweating indicate efficacy. Remaining wine can be drunk next day in moderation; cure occurs when wine is finished. Also excellent for Condyloma causing bone/joint pain unresponsive to other drugs. After 7 days of drinking, avoid wind for efficacy; observe dietary restrictions and abstain from sex.
Another Formula: Hu Mian San (Face-Protection Powder)
Composition: Woman's Hair (burnt to charcoal, retaining nature), Realgar (Ming Xiong Huang) (each 3 fen).
Grind finely, mix with half a wine-cup of Sesame Oil. Take with boiling Yellow Wine, 3 times daily.
[Verse] Hu Mian San treats emerging Chancre, preventing toxins from attacking head/face; mix with Sesame Oil, take with Yellow Wine; only Realgar and burnt hair used.
Another Formula: Cui Yun San (Emerald Cloud Powder)
Composition: Calomel (Qing Fen, 1 liang), Gypsum Fibrosum (Shi Gao, calcined, 1 liang), Toad Venom Salt (Chan Fan), Malachite (Tong Lv) (each 5 qian).
Grind to ultra-fine powder. Sprinkle dry on wet lesions; for dry lesions, mix with male pig bile to a thick paste for application, 3 times daily. Spots will fade naturally.
[Verse] Cui Yun San removes post-chancre spots; Calomel, Gypsum, Toad Venom Salt; Malachite ground together, sprinkle dry on wet lesions; Pig bile moistens dry lesions.
Another Formula: E Huang San (Goose Yellow Powder)
Composition: Calomel (Qing Fen), Gypsum Fibrosum (Shi Gao, calcined), Phellodendron Bark (Huang Bo, stir-fried) (equal parts).
Grind to powder. Sprinkle dry on affected areas to form scabs; reapply if ulcerated again. Cure upon complete toxin elimination.
[Verse] E Huang San treats ulcerated Chancre, pus/filth spreading and painful; Calomel, Gypsum, Phellodendrum ground; dry sprinkling stops pain and detoxifies effectively.
Another Formula: Hu Cong Wan (Attendant-Protecting Pill)
Composition: Realgar (Xiong Huang), Sichuan Pepper (Chuan Jiao) (each 5 qian), Apricot Kernel (Xing Ren, stir-fried, peeled, de-seeded).
Grind to powder, make pills with flour paste using Shaoxing Wine, size of Sophora seeds. Take 15 pills per dose, wash down with plain boiled water.
[Verse] Hu Cong Wan prevents Chancre infection; Realgar, Chuan Jiao 5 qian each; 100 Apricot Kernels, wine-paste pills; attendants take them to prevent transmission.
Another Formula: Jiu Long Dan (Nine Dragons Pill) (See section on Perineal Abscess below)