东垣李明之曰。诸 疹皆从寒水逆流而作也。子之初生也。在母腹中。母呼亦呼。母吸亦吸。呼吸者阳也。
而动作生焉。饥食母血。渴饮母血。饮食者阴也。而形质生焉。阴具阳足。十月而降。口中恶血。因啼即下。却
归男子生精之所。女子结胎之处。命宗所谓玄牝玄关者也。此血僻伏而不时发。或因乳食内伤。或因湿
热下溜。营气不从。逆于肉理。所僻伏者。乃为所发。初则膀胱壬水挟脊逆流。而克小肠丙火。故颈项以上
先见也。次则肾经癸水。又克心火。故胸腹以上次见也。终则二火炽盛。反制寒水。故胸腹以下后见也。至
此则五脏六腑皆病也。七日齐。七日盛。七日谢。三七二十一日而愈者。七日为火数故也。愈后或有疽病
疮者。是皆余毒尚在。今其病目者亦然。与风热不制之病。稍同而异。总以羚羊角散主之。便不硬者减硝
黄。未满二十一日而病作者。消毒化 汤主之。此药功非独能于目。盖专于 者之药也。不问初起已着。
服之便令消化。稀者则不复出。方随四时加减。
羚羊角散（治小儿 痘后。余毒不解。上攻眼目。生翳羞明。眵泪俱多。红赤肿闭。）
草决明 芒硝 升麻 防风 车前子 黄芩 黄 大黄 羚羊角（将角细锉俱各等分）
上为末。每服二钱。水一钟。煎至半钟。去滓温服。
上方以羚羊角主明目为君。升麻补足太阴以实内。逐其毒也。黄 补手太阴以实外。御其邪也。为臣。
防风升清阳。车前子泻浊阴。为佐。草决明疗赤痛泪出。黄芩、大黄、芒硝用以攻其固热。为使。然大黄、芒
硝乃大苦寒之药。智者当量其虚实。以为加减。未满二十一日而疾作者。消毒化 汤主之。
消毒化 汤（治小儿 疹未满二十一日而目疾作者。余证同上。）
柴胡 本 生地黄 连翘 细辛 黄柏（酒制） 川黄连
当归 甘草（各四分） 花粉 吴茱萸 白术 苏木 陈皮 干葛根（各二分） 麻黄 防风
升麻 川羌活（各五分） 黄芩（酒制） 苍术（泔水制） 川芎（各三分）
上锉剂。水二钟。煎至一钟。去滓温服。
上方功非独能于目。盖专于 而置也。今以治 之剂治目者。以其毒尚炽盛。又傍害于目也。夫 疹
之发。初在膀胱。壬水克小肠丙火。羌活。 本。乃治足太阳之药。次则肾经癸水。又克心火。细辛主少阴
之药。故为君。终则二火炽盛。反制寒水。故为臣。麻黄、防风、川芎。升发阳气。祛诸风邪。葛根、柴胡。解利邪
毒。升麻散诸郁结。白术、苍术。除湿和胃。生甘草大退诸热为佐。气不得上下。吴茱萸、陈皮通之。血不得
流行。红花、苏木顺之。当归愈恶疮。连翘除客热。故为使。此方君臣佐使。逆从反正。用药治法俱备。通造
化。明药性者。能知也。如未见 疹之前。小儿耳尖冷。呵欠。睡中惊。喷嚏。眼涩。知其必出 者。急以此药
投之。甚者则稀。稀者立已。已后无复出之患。
李东垣（李明之）说：所有的疹病，都是从寒水逆流而引发的。婴儿刚出生时，在母腹中，母亲呼气他也呼气，母亲吸气他也吸气。呼吸属于阳，动作由此产生；饥饿时吃母亲的血，口渴时喝母亲的血，饮食属于阴，形体质料由此生成。阴气完备、阳气充足，经过十个月便降生下来。口中的恶血，因为啼哭随即排出，又回归到男子生成精液的地方，女子结胎之处，也就是命门宗筋所说的“玄牝”和“玄关”。这些血液僻伏潜藏而不及时发散，或者因为乳食内伤，或者因为湿热下注，营气运行不畅，逆乱于肌肉纹理之间，那些僻伏的血液，就被激发出来。起初是膀胱壬水挟带脊柱逆流，从而克制小肠丙火，所以颈项以上先出现症状。接着是肾经癸水，又克制心火，所以胸腹以上随后出现。最后是两火炽盛，反过来制约寒水，所以胸腹以下最后出现。到了这个阶段，五脏六腑都受到影响了。病程七天整齐（指皮疹出齐），七天达到鼎盛，七天开始消退，三七二十一天痊愈，这是因为七是火数的缘故。痊愈后如果有疽疮等病症，都是余毒尚存。现在这个病发生在眼睛上也是如此，与风热不能制约的病证，稍微相同但又有差异。总体都用羚羊角散来主治。如果大便不硬，就减少芒硝和大黄的用量。未满二十一天而发病的，用消毒化斑汤主治。这药的功效不仅仅在于治眼，更是专门治疗痘疹的药物。不论初起还是已经发作，服用它就能让毒邪消散，稀疏的就不再发出。方剂根据四季变化进行加减。
羚羊角散（治疗小儿痘疹后，余毒不解，向上攻冲眼目，导致生翳膜、羞明、眼屎眼泪俱多、红赤肿胀闭合。）
草决明、芒硝、升麻、防风、车前子、黄芩、黄芪、大黄、羚羊角（将角细锉，各等分）
以上药物研为末。每次服用二钱，用水一钟，煎至半钟，去渣温服。
上方以羚羊角为主药（君药），主要作用是明目；升麻补益太阴经以充实内部，驱逐毒邪；黄芪补益手太阴经以充实外部，抵御外邪，这两味作为辅药（臣药）；防风提升清阳，车前子泻除浊阴，作为佐药；草决明治疗红痛流泪，黄芩、大黄、芒硝用来攻逐固结的热邪，作为使药。然而大黄、芒硝是大苦大寒的药物，明智的人应当衡量患者的虚实情况，来进行加减。未满二十一天而发病的，用消毒化斑汤主治。
消毒化斑汤（治疗小儿痘疹未满二十一天而发生眼疾的。其他证候同上。）
柴胡、藁本、生地黄、连翘、细辛、黄柏（酒制）、川黄连、当归、甘草（各四分）、花粉、吴茱萸、白术、苏木、陈皮、干葛根（各二分）、麻黄、防风、升麻、川羌活（各五分）、黄芩（酒制）、苍术（泔水制）、川芎（各三分）
以上切碎成剂。用水二钟，煎至一钟，去渣温服。
上方的功效不仅仅在于治眼，更是专门为痘疹而设立的。现在用治疗痘疹的方剂来治疗眼病，是因为毒邪仍然炽盛，又旁及伤害眼睛。痘疹的发作，起初在膀胱，壬水克制小肠丙火，羌活、藁本是治疗足太阳经的药物，所以作为君药；接着是肾经癸水，又克制心火，细辛是主入少阴经的药物，所以作为臣药；最后是两火炽盛，反过来制约寒水，所以（此处原文逻辑似有省略或特指，结合上下文理解为针对后续病机的药物配合）作为佐使。麻黄、防风、川芎，升发阳气，祛除各种风邪；葛根、柴胡，解利邪毒；升麻疏散各种郁结；白术、苍术，除湿和胃；生甘草大大退除各种热邪，作为佐药；气机不能上下通畅，用吴茱萸、陈皮来通利；血液不能流行，用红花、苏木来顺行；当归治愈恶疮，连翘清除客热，所以作为使药。此方的君臣佐使，逆从反正，用药治法都具备齐全，通达造化，明了药性的人，能够理解。如果在未见痘疹之前，小儿耳尖冷，呵欠，睡中惊悸，喷嚏，眼涩，知道必然要出痘疹，急忙用此药投服。严重的就会变得稀疏，稀疏的立刻痊愈。此后没有再次复发的隐患。
Li Dongyuan (Li Mingzhi) stated: All rashes arise from the retrograde flow of cold water. When a child is first born, while in the mother's womb, he breathes when the mother breathes out and breathes in when the mother inhales. Respiration belongs to Yang, and movement arises from it. When hungry, he consumes the mother's blood; when thirsty, he drinks the mother's blood. Diet and drink belong to Yin, and physical form and substance are generated from them. With Yin complete and Yang sufficient, after ten months, the child descends. The foul blood in the mouth is expelled immediately upon crying, returning to the place where men generate essence and where women conceive the fetus, which is what the *Mingzong* refers to as the "Xuanpin" (Mysterious Female) and "Xuanguan" (Mysterious Portal). This blood lies latent and does not disperse timely. It may be triggered by internal injury from milk and food, or by damp-heat flowing downward. When Ying Qi (Nutritive Qi) fails to circulate smoothly and reverses within the muscle tissue, the latent blood is stimulated to erupt. Initially, Bladder Ren Water flows retrogradely along the spine, overcoming Small Intestine Bing Fire, so symptoms appear first above the neck. Subsequently, Kidney Gui Water overcomes Heart Fire, so symptoms appear next above the chest and abdomen. Finally, the two Fires become blazing hot and counter-restrict Cold Water, so symptoms appear last below the chest and abdomen. At this stage, all Zang and Fu organs are affected. The disease progresses through seven days of completion (eruption full), seven days of peak intensity, and seven days of resolution, healing in twenty-one days (3 x 7), because seven is the number associated with Fire. After recovery, if carbuncles or sores occur, these are due to residual toxins still present. Now, this disease affecting the eyes is similar; it is slightly alike yet distinct from diseases caused by uncontrolled Wind-Heat. Generally, it is treated primarily with Lingyang Jiao San (Antelope Horn Decoction). If the stool is not hard, reduce the dosage of Mangxiao (Natrii Sulfas) and Dahuang (Rhei Radix et Rhizoma). If the disease occurs before twenty-one days have passed, Xiaodu Huaban Tang (Detoxifying and Transforming Macules Decoction) is used. The efficacy of this medicine is not limited to treating the eyes; it is specifically a remedy for variola/rash diseases. Whether in the early stages or fully developed, taking it will cause the toxin to dissipate; if the rash is sparse, it will not reappear. The formula is modified according to the four seasons.
Lingyang Jiao San (Antelope Horn Decoction) (Treats post-variolal residual toxins that fail to resolve, attacking upward to the eyes, causing nebulae, photophobia, excessive discharge and tearing, redness, swelling, and closure.)
Jueming (Cassiae Semen), Mangxiao (Natrii Sulfas), Shengma (Cimicifugae Rhizoma), Fangfeng (Saposhnikoviae Radix), Cheqianzi (Plantaginis Semen), Huangqin (Scutellariae Radix), Huangqi (Astragali Radix), Dahuang (Rhei Radix et Rhizoma), Lingyangjiao (Saigae Tataricae Cornu) (The horn is finely sliced; all ingredients are in equal parts).
Grind the above into powder. Take 2 qian per dose. Add one zhong of water, decoct until half a zhong remains, remove the dregs, and take warm.
In the above formula, Lingyangjiao (Saigae Tataricae Cornu) serves as the Jun (Monarch) herb, primarily for brightening the eyes; Shengma (Cimicifugae Rhizoma) tonifies the Taiyin channel to solidify the interior and expel toxins; Huangqi (Astragali Radix) tonifies the Hand-Taiyin channel to solidify the exterior and resist pathogens, serving as the Chen (Minister) herbs; Fangfeng (Saposhnikoviae Radix) raises clear Yang, and Cheqianzi (Plantaginis Semen) drains turbid Yin, serving as the Zuo (Assistant) herbs; Jueming (Cassiae Semen) treats redness, pain, and tearing; Huangqin (Scutellariae Radix), Dahuang (Rhei Radix et Rhizoma), and Mangxiao (Natrii Sulfas) are used to attack consolidated heat, serving as the Shi (Envoy) herbs. However, Dahuang and Mangxiao are greatly bitter and cold medicines. Wise practitioners should assess the patient's deficiency or excess to adjust the dosages. For diseases occurring before twenty-one days, Xiaodu Huaban Tang (Detoxifying and Transforming Macules Decoction) is used.
Xiaodu Huaban Tang (Detoxifying and Transforming Macules Decoction) (Treats eye diseases arising in children with variola/rash before twenty-one days have passed. Other symptoms are the same as above.)
Chaihu (Bupleuri Radix), Gaoben (Ligustici Chuanxiong Rhizoma), Shengdihuang (Rehmanniae Radix Preparata), Lianqiao (Forsythiae Fructus), Xixin (Asari Radix et Rhizoma), Huangbai (Phellodendri Cortex) (prepared with wine), Chuanlianzhong (Coptidis Rhizoma), Danggui (Angelicae Sinensis Radix), Gancao (Glycyrrhizae Radix et Rhizoma) (each 4 fen), Huafen (Trichosanthis Radix), Wuzhuyu (Evodiae Fructus), Baizhu (Atractylodis Macrocephalae Rhizoma), Sumu (Pterocarpus Santalinus Lignum), Chenpi (Citri Reticulatae Pericarpium), Gegen (Puerariae Lobatae Radix) (each 2 fen), Mahuang (Ephedrae Herba), Fangfeng (Saposhnikoviae Radix), Shengma (Cimicifugae Rhizoma), Chuanqianghuo (Notopterygii Rhizoma et Radix) (each 5 fen), Huangqin (Scutellariae Radix) (prepared with wine), Cangzhu (Atractylodis Rhizoma) (processed with rice water), Chuanxiong (Ligustici Chuanxiong Rhizoma) (each 3 fen).
Cut into pieces. Add two zhongs of water, decoct until one zhong remains, remove the dregs, and take warm.
The efficacy of the above formula is not limited to treating the eyes; it is specifically established for treating variola/rash. The reason for using a variola/rash formula to treat eye disease now is that the toxin is still blazing hot and has spread to affect the eyes. The eruption of variola/rash begins in the Bladder, where Ren Water overcomes Small Intestine Bing Fire. Qianghuo (Notopterygii Rhizoma et Radix) and Gaoben (Ligustici Chuanxiong Rhizoma) are herbs for the Foot-Taiyang channel, thus serving as the Jun (Monarch); subsequently, Kidney Gui Water overcomes Heart Fire. Xixin (Asari Radix et Rhizoma) enters the Shaoyin channel, thus serving as the Chen (Minister); finally, the two Fires blaze, counter-restricting Cold Water. Mahuang (Ephedrae Herba), Fangfeng (Saposhnikoviae Radix), and Chuanxiong (Ligustici Chuanxiong Rhizoma) raise and diffuse Yang Qi and dispel various wind pathogens. Gegen (Puerariae Lobatae Radix) and Chaihu (Bupleuri Radix) resolve and benefit against toxic pathogens. Shengma (Cimicifugae Rhizoma) disperses various stagnations. Baizhu (Atractylodis Macrocephalae Rhizoma) and Cangzhu (Atractylodis Rhizoma) eliminate dampness and harmonize the Stomach. Raw Gancao (Glycyrrhizae Radix et Rhizoma) greatly reduces various heats, serving as the Zuo (Assistant). When Qi cannot move up and down, Wuzhuyu (Evodiae Fructus) and Chenpi (Citri Reticulatae Pericarpium) unblock it. When Blood cannot circulate, Honghua (Carthami Flos) and Sumu (Pterocarpus Santalinus Lignum) smooth it. Danggui (Angelicae Sinensis Radix) heals malignant sores, and Lianqiao (Forsythiae Fructus) removes pathogenic heat, serving as the Shi (Envoy). The Jun, Chen, Zuo, and Shi roles, along with contrary and direct approaches, are fully prepared in this formula. Those who understand the transformations of nature and the properties of medicines can comprehend it. Before the appearance of variola/rash, if a child has cold ear tips, yawning, startle during sleep, sneezing, and dry/itchy eyes, one knows that variola/rash will inevitably emerge. Immediately administer this medicine. Severe cases will become sparse; sparse cases will heal immediately. Thereafter, there is no risk of recurrence.