疳之新者为热疳，面黄脸赤，骨热盗汗，鼻干口臭，唇焦烦渴，心躁惊悸，情
意不乐，若疳之久者为冷疳，目肿腹胀，便利不定，泻粪肥腻，或似油珠，烦渴黄
瘦。热疳病多在外，冷疳病多在内。又有冷热二证交互，非新非久，不内外因者。
木香丸治冷疳
木香 青黛（另研） 槟榔 肉豆蔻（去皮。各一分） 麝香（另研，一钱半） 续随子（一两半，炒） 虾
蟆（三个，先用绳系、晒干，烧、存性）
上末，蜜丸如绿豆大。每服三五丸至一二十丸，薄荷汤下，食前。
汤氏云∶小儿冷疳，多渴，好卧冷地，烦躁啼叫，饮食不进，渐成羸瘦，其候
难明，有若热证，但大便滑泄，百药不效是也。因女子，百药俱试而无偶中者，
竟与钱氏木香丸，不数服而愈。自后凡有此证，无不获验。
胡黄连丸 治热疳
胡黄连 黄连（各半两） 朱砂（一分）
上，上二物为细末，研入朱砂末，都填入猪胆内，用淡浆于砂铫子内悬胎煮
一饭时久取出，研入芦荟、麝香各一分，饭丸如麻子大。每服五七丸至一二十丸，
米饮下，食后。一方，加虾蟆半两，不烧。
如圣丸 治冷热疳（方见疳泻）
巢氏∶儿面黄发直，时壮热，饮食不生肌肤，积经日月，遂致死者，谓之无辜。
言天上有鸟名无辜，昼伏夜游，洗濯小儿衣席，露之经宿，此鸟即飞从上过，
而取此衣与小儿着，并席与小儿卧，便令儿生此病。《圣惠》小儿无辜，脑后有核如弹
丸，捏之反下转是也，凡小儿有此物，如禽兽舌下有禁虫，若不速去，当损其命。
此核初生软而不痛，中有虫如米粉，得热气渐长大，大则筋结定，定即虫随血气流
散，所有停留，子母相生，侵蚀脏腑，肌肉作疮，或大便泄脓血，致使小儿渐渐黄
瘦，头大发立，手足细弱，从兹夭折也。夫小儿无辜疳痢者，大腹，泄痢脓血，毛
发皮肤枯槁，肌体日渐瘦羸，肠胃既虚，痢无时节，故名无辜疳痢也。汉东王先生
云∶小儿无辜疾者，古云天上有一鸟，名无辜，因晒小儿衣物失取过夜，遇此鸟过、
尿之，令儿啼叫，诸病所生，日渐黄瘦者非也。此盖是八邪所伤得之，其八邪者，
饥、饱、劳、役、风、惊、暑、积，谓之八邪，久则令人日渐黄瘦，吃食不长肌肉，
夜间多哭，身上或发微微壮热，多渴，吃食不知饥饱，或生疮癣是也。朱氏八片锦
歌∶孩子无辜气，多因母作为，若人能慎护，安得见 羸，惊薄成风疾，暄寒作气
痿，须交除病乳，莫更着重衣，吃食无令早，能言不怕迟，论中八不许，胸起力频
微，头皮光哲哲，毛发薄离离，肝壅侵双眼，脾黄入四肢，浑身生瘾疹，遍体是疮
痍，泻痢无休歇，憎寒少定时，绣球全罔顾，竹马岂能骑，白晕眸中现，清涎口畔
垂，斗牙须咬甲，举手要 眉，夜夜餐瓜果，朝朝食土泥，胃伤肠肚胀，肺盛喘何
疑，饮食无休歇，耽眠似醉迷。
肥儿丸 治小儿脑后项边，有物如弹子，按之转动，软而不痛，名无辜疳。久服神效。
胡黄连 神曲（炒） 麦 （各五钱） 槟榔（三钱） 木香（二钱） 肉豆蔻（面裹煨） 使君子肉（各二钱半）
上为细末，蒸饼丸如，黍米大。用米饮，食远服。
《圣惠》鳖甲散 治小儿无辜疳，项细肚大，毛发干立作穗。
鳖甲（三分，涂醋炙黄，去裙 ） 槟榔（三颗） 沉香 漏芦 牛蒡子（微炒） 使君子 赤芍药
诃梨勒皮 甘草（炙微赤，锉。各半两）
上件捣，罗为散。每服一钱，以水一小盏，煎至五分，去渣，不计时候，量儿大小分减温服。
〔张涣〕蝎虎丹 截疳祛毒。
干蝎虎（雄者，微炙，一枚） 蜗牛壳 兰香根 淀花（各一分。以上捣罗为细末，次入） 雄黄（水磨者
细研） 麝香（细研。各一分） 龙脑（半分，细研）
上件通拌匀，煎米醋打白面糊、和如黍米大。每服十粒，煎脂麻汤下，乳食后。
香甲汤 截疳辟邪。
漏芦（一两） 沉香（锉） 牛蒡子（微炒） 诃梨勒皮（微炮） 安息香 鳖甲（涂酥炙黄，去裙 ） 乳香（研。
各半两）
上件捣，罗为细末，同乳香拌匀。每服一钱，水八分，入人参少许，煎四分，
去滓放温热服，量儿大小加减。
〔张涣〕玉粉散 无辜疳痢 定痢截疳。
胡粉（一两） 白龙骨 水磨雄黄（各研，微炒） 楮木根白皮 漏芦 白马夜眼（洗净，焙干。各半两）
上件捣，罗为细末，都拌匀。每服一字至半钱，以鸡卵清调下，乳食前。
二肝丹 治无辜疳痢不止。
地胆草 菖蒲（一寸九节者） 漏芦（各一两） 胡黄连 地榆（各半两。以上捣罗为细末，次用） 鸡肝
（薄切） 猪肝（同入盐少许，用诸药煮肝熟。各一两）
上件，同于石臼中捣一二百下成膏和丸，如黍米大。每服十粒，麝香汤下，食前，量儿大小加减。
梅肉散 治无辜疳渴利不止，眼出障翳，身体浮肿。
乌梅肉（炒干） 绵黄 干葛（各一两） 川黄连 栝蒌根 干姜（炮） 甘草（炙。各半两）
上件捣，罗为细末。每服一钱，水一盏，煎至六分，去滓放温，时时与服。
蓝叶汤 治无辜疳，血痢不断。
蓝叶（一两） 地龙 人参（去芦头） 乌梅肉 冬瓜仁 黄连 赤茯苓 蜗牛壳（微炒。各半两）
上件捣，罗为细末。每服一钱，水一小盏，煎至六分，去滓温服，乳食前。
天灵丹 治无辜疳，痢久不瘥。
天灵盖（一个） 干蟾（一两，烧灰） 胡黄连 莨菪子（水淘去浮者，炒令黑色。各半两） 砒霜（一分，同天
灵盖、湿纸三五重裹，胶泥固济，于大炭火上烧令通赤，取出候冷。以上都捣罗为细末，次入） 麝香（一分）
上件都拌匀，软饭和丸，如黍米大。每服五粒，乳汁下，量儿大小加减服之。
温脏汤 治小儿无辜疳痢久不止，手足逆冷。
肉豆蔻（去壳） 干姜（炮。各一两） 龙骨 当归 浓朴（去粗皮，涂生姜汁炙令香熟。各半两） 附子（一枚，
重半两，炮，去皮脐）
茅香（半分，锉）
上件捣，罗为细末。每服一钱，水八分一盏，入生姜三片，煎至五分，去滓温服，乳食前。
朴附丹 治无辜疳痢，赤白相杂。
浓朴（涂生姜汁炙令香熟） 诃梨勒皮（面裹、炮。各一两） 附子（一枚，炮，去皮脐） 龙骨 乌梅肉 赤
石脂（各半两）
上件捣，罗为细末，炼蜜和丸，如黍米大。每服十粒，米饮下，乳食前。
人中白散 治小儿无辜疳气，寒热积滞不化，腹肚胀痛。
人中白（一分） 麝香（半分） 虾蟆（涂酥炙焦） 芦荟（各半两）
上件药细研为散。每日空心及晚后，用熟水调下半钱。服后当下恶物。量儿大小，加减服之。
朱砂丸 治小儿一切无辜疳，黄瘦腹痛，或痢有虫，冷之与热悉主之。
朱砂（一分，细研。一方用三分） 菖蒲 漏芦（各一两） 雄黄（一分，细研。一方用三分） 干蟾（一枚，醋
炙令黄） 麝香（一两，细研。一方用一分，《万全方》亦用一分）
上件药捣，罗为末，都研令匀，用粟米饭和丸，如麻子大。每服以粥饮化下二
丸，空心午后各一服，随儿大小，以意加减。
决明子丸 治小儿冷热无辜疳，或时惊热，或时夜啼，大便青黄白汁，头热身热，
头发作穗，四肢黄瘦，不多食物。
用马蹄决明子二两，捣、罗为末，炼蜜和丸，如麻子大。每于食后，以熟水下
三丸，更量儿大小，加减服之。
漏芦散 治小儿无辜疳，肚胀或时泻痢，冷热不调。
用漏芦一两，捣细，罗为散。每以猪肝一两，散子一钱，盐少许斟酌，以水煮
熟，空心顿服，粥饮下。
漏芦丸 治小儿无辜疳痢，羸弱不欲饮食。及腹内虫动作，多吐清水。
漏芦（二两） 猪肝（爆干） 楮株根白皮（锉，各一两）
上件药捣，罗为末，炼蜜和，捣一二百杵，丸如弹子大。每服以温水研一丸，
不计时候，量儿大小，分减服之。
《圣惠》又方 用地胆子一两，捣细，罗为末，每服一钱，以猪肝一两，入盐少许煮
熟，无时，量儿大小分减食之。
治小儿无辜疳痢不止方
上用没石子二枚，炒令赤黑色，捣细，罗为散，以面半匙，和作饼子，爆熟，
却研为末。不计时候，以粥饮调下半钱，量儿大小，加减服之。
《外台·备急》治小儿无辜疳痢方
当归 龙骨 黄连 人参 没石子 甘草（炙。各一两）
上六味捣散，蜜丸。服三丸，日再，以瘥为度。大小增减量之。
《外台·救急》疗小儿瘦头干无辜兼痢方
上用马齿苋捣绞汁，服三合，以瘥止。
《子母秘录》治小儿无辜痢赤白兼成疳方
上用胡粉熟蒸，熬令色变，以饮服之。
《传验》治一岁至两岁小儿无辜病方
上用夜明砂熬捣为散，任意拌饭并吃食与吃。三岁，号干无辜。
疳证中新发的称为热疳，症状表现为面色黄而脸颊红赤，骨骼发热、夜间盗汗，鼻干、口臭，嘴唇焦裂、心烦口渴，心中烦躁、惊悸不安，情绪低落不快乐。如果疳证病程较长的则称为冷疳，症状表现为眼睑肿胀、腹部胀满，大便次数不定，泻下的粪便肥腻，或者像油珠一样，伴有烦渴、身体发黄且消瘦。热疳的病位多在体表（外），冷疳的病位多在体内（内）。又有冷热两种证候相互交错，既不是新病也不是久病，不属于内因或外因的情况。
木香丸用于治疗冷疳。
药材：木香、青黛（单独研磨）、槟榔、肉豆蔻（去皮，各一分）、麝香（单独研磨，一钱半）、续随子（一两半，炒制）、虾蟆（三个，先用绳子系住、晒干，烧制至存性）。
制法：将上述药物研成细末，用蜂蜜制成如绿豆大小的丸剂。每次服用三到五丸至一二十丸，用薄荷汤送服，饭前服用。
汤氏说：小儿冷疳，大多口渴，喜欢躺在凉地上，烦躁啼哭叫喊，饮食不进，逐渐形成消瘦羸弱，其症状难以明确辨认，看起来像热证，但大便滑泄不止，各种药物都无效。有一位女子，尝试了百种药物都没有一次见效的，最终给予钱乙的木香丸，不到几服药就痊愈了。从此以后，凡是遇到这种证候，没有不获得验证有效的。
胡黄连丸 治疗热疳。
药材：胡黄连、黄连（各半两）、朱砂（一分）。
制法：将前两种药研成细末，把朱砂末填入猪胆内，用淡浆水在砂锅中悬挂猪胆煮一顿饭的时间后取出，再加入芦荟、麝香各一分，用米饭和药粉制成如麻子大小的丸剂。每次服用五七丸至一二十丸，用米饮送服，饭后服用。另一配方，加虾蟆半两，不烧制。
巢元方说：小儿面色黄、头发直竖，时常壮热，饮食不能转化为肌肤营养，经过日月积累，最终导致死亡的，称为无辜疳。传说天上有鸟名叫无辜，白天潜伏夜晚活动，洗涤小儿的衣物席子，露水经过一夜，这只鸟就从上面飞过，取走这些衣服给小儿穿，以及席子给小儿睡，便让小儿生出此病。《太平圣惠方》记载的小儿无辜疳，脑后有核状物如弹丸大小，捏它时反而能转动，这就是。凡是有小儿长有此物，就像禽兽舌下有禁虫一样，如果不迅速去除，会损害性命。这个核初生时软且不痛，里面有虫像米粉一样，得到热气后逐渐长大，大了之后筋脉结定，定了之后虫随着气血流散，所有停留之处，子母相生，侵蚀脏腑，肌肉生疮，或者大便泄出脓血，致使小儿渐渐黄瘦，头大头发直立，手足细弱，从此夭折。所谓小儿无辜疳痢，是大腹、泄痢脓血、毛发皮肤枯槁、肌体日渐消瘦羸弱，肠胃既然虚弱，痢疾没有定时，所以叫无辜疳痢。汉东王先生说：小儿无辜疾，古云天上有一鸟名无辜，因为晒小儿衣物丢失过夜，遇到此鸟飞过、排泄尿液，令小儿啼叫，诸病所生，日渐黄瘦的说法是不对的。这其实是八邪所伤导致的，所谓的八邪是：饥、饱、劳、役、风、惊、暑、积，称为八邪，时间久了让人日渐黄瘦，吃东西不长肌肉，夜间多哭，身上有时发微微壮热，多渴，吃东西不知饥饱，或者生疮癣等。朱氏《八片锦歌》唱道：孩子患无辜气，多因母亲行为不当所致。若人能谨慎护养，怎会见到消瘦羸弱？惊恐薄寒成风疾，冷暖作气痿，必须除去病乳，不要再着重厚衣，吃饭不要过早，能说话不怕晚，论中有八不许，胸起力气频繁微弱，头皮光亮，毛发稀薄稀疏，肝壅侵犯双眼，脾黄进入四肢，浑身生瘾疹，遍体是疮痍，泻痢无休歇，憎寒少定时，绣球全不顾，竹马岂能骑，白晕眸中现，清涎口畔垂，斗牙须咬甲，举手要抓眉，夜夜餐瓜果，朝朝食土泥，胃伤肠肚胀，肺盛喘何疑，饮食无休歇，耽眠似醉迷。
肥儿丸 治疗小儿脑后项边，有物如弹子，按之转动，软而不痛，名为无辜疳。长期服用神效。
药材：胡黄连、神曲（炒）、麦麸（各五钱）、槟榔（三钱）、木香（二钱）、肉豆蔻（面裹煨）、使君子肉（各二钱半）。
制法：研为细末，用蒸饼和药粉制成如黍米大小的丸剂。用米饮送服，离进食时间较远时服用。
《太平圣惠方》鳖甲散 治疗小儿无辜疳，颈细肚大，毛发干枯直立如穗状。
药材：鳖甲（三分，涂醋炙黄，去裙襕）、槟榔（三颗）、沉香、漏芦、牛蒡子（微炒）、使君子、赤芍药、诃梨勒皮、甘草（炙微赤，锉碎，各半两）。
制法：将上述药物捣碎，过筛为散剂。每次服用一钱，用水一小盏，煎至五分，去渣，不限时候，根据小儿大小分次温服。
〔张涣〕蝎虎丹 截断疳毒祛除湿毒。
药材：干蝎虎（雄性，微炙，一枚）、蜗牛壳、兰香根、淀花（各一分。以上捣罗为细末，次入）雄黄（水磨者细研）、麝香（细研，各一分）、龙脑（半分，细研）。
制法：将上述药物通拌匀，用米醋打白面糊，调和如黍米大小。每次服用十粒，煎脂麻汤送下，乳食后服用。
香甲汤 截断疳病辟除邪气。
药材：漏芦（一两）、沉香（锉碎）、牛蒡子（微炒）、诃梨勒皮（微炮）、安息香、鳖甲（涂酥炙黄，去裙襕）、乳香（研，各半两）。
制法：将上述药物捣碎，过筛为细末，同乳香拌匀。每次服用一钱，水八分，加入少许人参，煎至四分，去滓放温热服用，根据小儿大小加减。
〔张涣〕玉粉散 治疗无辜疳痢，止痢截疳。
药材：胡粉（一两）、白龙骨、水磨雄黄（各研，微炒）、楮木根白皮、漏芦、白马夜眼（洗净，焙干，各半两）。
制法：将上述药物捣碎，过筛为细末，都拌匀。每次服用一字至半钱，用鸡卵清调下，乳食前服用。
二肝丹 治疗无辜疳痢不止。
药材：地胆草、菖蒲（一寸九节者）、漏芦（各一两）、胡黄连、地榆（各半两。以上捣罗为细末，次用）鸡肝（薄切）、猪肝（同入盐少许，用诸药煮肝熟，各一两）。
制法：将上述药物同于石臼中捣一二百下成膏和丸，如黍米大小。每次服用十粒，麝香汤送下，饭前服用，根据小儿大小加减。
梅肉散 治疗无辜疳渴利不止，眼出障翳，身体浮肿。
药材：乌梅肉（炒干）、绵黄耆、干葛（各一两）、川黄连、栝蒌根、干姜（炮）、甘草（炙，各半两）。
制法：将上述药物捣碎，过筛为细末。每次服用一钱，水一盏，煎至六分，去滓放温，时时与服。
蓝叶汤 治疗无辜疳，血痢不断。
药材：蓝叶（一两）、地龙、人参（去芦头）、乌梅肉、冬瓜仁、黄连、赤茯苓、蜗牛壳（微炒，各半两）。
制法：将上述药物捣碎，过筛为细末。每次服用一钱，水一小盏，煎至六分，去滓温服，乳食前服用。
天灵丹 治疗无辜疳，痢久不愈。
药材：天灵盖（一个）、干蟾（一两，烧灰）、胡黄连、莨菪子（水淘去浮者，炒令黑色，各半两）、砒霜（一分，同天灵盖、湿纸三五重裹，胶泥固济，于大炭火上烧令通赤，取出候冷。以上都捣罗为细末，次入）麝香（一分）。
制法：将上述药物都拌匀，软饭和丸，如黍米大小。每次服用五粒，乳汁送下，根据小儿大小加减服用。
温脏汤 治疗小儿无辜疳痢久不止，手足逆冷。
药材：肉豆蔻（去壳）、干姜（炮，各一两）、龙骨、当归、浓朴（去粗皮，涂生姜汁炙令香熟，各半两）、附子（一枚，重半两，炮，去皮脐）、茅香（半分，锉）。
制法：将上述药物捣碎，过筛为细末。每次服用一钱，水八分一盏，加入生姜三片，煎至五分，去滓温服，乳食前服用。
朴附丹 治疗无辜疳痢，赤白相杂。
药材：浓朴（涂生姜汁炙令香熟）、诃梨勒皮（面裹、炮，各一两）、附子（一枚，炮，去皮脐）、龙骨、乌梅肉、赤石脂（各半两）。
制法：将上述药物捣碎，过筛为细末，炼蜜和丸，如黍米大小。每次服用十粒，米饮送下，乳食前服用。
人中白散 治疗小儿无辜疳气，寒热积滞不化，腹肚胀痛。
药材：人中白（一分）、麝香（半分）、虾蟆（涂酥炙焦）、芦荟（各半两）。
制法：将上述药物细研为散剂。每日空腹及晚后，用熟水调下半钱。服后当下恶物。根据小儿大小，加减服用。
朱砂丸 治疗小儿一切无辜疳，黄瘦腹痛，或痢有虫，冷之与热悉主之。
药材：朱砂（一分，细研。一方用三分）、菖蒲、漏芦（各一两）、雄黄（一分，细研。一方用三分）、干蟾（一枚，醋炙令黄）、麝香（一两，细研。一方用一分，《万全方》亦用一分）。
制法：将上述药物捣碎，过筛为末，都研令匀，用粟米饭和丸，如麻子大小。每次以粥饮化下二丸，空心午后各一服，随儿大小，以意加减。
决明子丸 治疗小儿冷热无辜疳，或时惊热，或时夜啼，大便青黄白汁，头热身热，头发作穗，四肢黄瘦，不多食物。
药材：马蹄决明子二两。
制法：捣、罗为末，炼蜜和丸，如麻子大小。每于食后，以熟水下三丸，更量儿大小，加减服用。
漏芦散 治疗小儿无辜疳，肚胀或时泻痢，冷热不调。
药材：漏芦一两。
制法：捣细，罗为散。每以猪肝一两，散子一钱，盐少许斟酌，以水煮熟，空心顿服，粥饮下。
漏芦丸 治疗小儿无辜疳痢，羸弱不欲饮食。及腹内虫动作，多吐清水。
药材：漏芦（二两）、猪肝（爆干）、楮株根白皮（锉，各一两）。
制法：将上述药物捣，罗为末，炼蜜和，捣一二百杵，丸如弹子大小。每次以温水研一丸，不计时候，量儿大小，分减服用。
《太平圣惠方》又方：用地胆子一两，捣细，罗为末，每服一钱，以猪肝一两，入盐少许煮熟，无时，量儿大小分减食之。
治小儿无辜疳痢不止方：
上用没石子二枚，炒令赤黑色，捣细，罗为散，以面半匙，和作饼子，爆熟，却研为末。不计时候，以粥饮调下半钱，量儿大小，加减服用。
《外台·备急》治小儿无辜疳痢方：
药材：当归、龙骨、黄连、人参、没石子、甘草（炙，各一两）。
制法：上六味捣散，蜜丸。服三丸，日再，以瘥为度。大小增减量之。
《外台·救急》疗小儿瘦头干无辜兼痢方：
上用马齿苋捣绞汁，服三合，以瘥止。
《子母秘录》治小儿无辜痢赤白兼成疳方：
上用胡粉熟蒸，熬令色变，以饮服之。
《传验》治一岁至两岁小儿无辜病方：
上用夜明砂熬捣为散，任意拌饭并吃食与吃。三岁，号干无辜。
New-onset Gan syndrome is called Heat Gan, presenting with a sallow complexion and reddish cheeks, bone fever, night sweats, dry nose, foul breath, cracked lips, irritability, thirst, mental restlessness, palpitations, low mood, and unhappiness. If the Gan syndrome has persisted for a long time, it is called Cold Gan, presenting with swollen eyelids, abdominal distension, irregular bowel movements, greasy stools or those resembling oil droplets, accompanied by irritability, thirst, yellowish discoloration, and emaciation. Heat Gan typically involves pathology in the exterior (body surface), while Cold Gan typically involves pathology in the interior (internal organs). There are also cases where cold and heat syndromes interact, neither new nor old, and not attributable to internal or external causes.
Muxiang Wan (Aucklandia Pill) treats Cold Gan.
Ingredients: Muxiang (Costus Root), Qingdai (Indigo Naturalis, separately ground), Binglang (Areca Seed), Roudoukou (Nutmeg, peeled; each 1 fen), Shexiang (Musk, separately ground, 1.5 qian), Xuisui Zi (Euphorbia Seed, 1.5 liang, stir-fried), Hamo (Toad, three pieces, tied with string, dried, burned until carbonized but retaining efficacy).
Preparation: Grind the above ingredients into fine powder, mix with honey to form pills the size of mung beans. Take 3–5 pills up to 10–20 pills per dose, washed down with Bohe Tang (Mint Decoction), before meals.
Master Tang stated: Children with Cold Gan often experience excessive thirst, prefer lying on cool surfaces, exhibit irritability and crying, refuse food, and gradually become emaciated. The symptoms are difficult to clarify, resembling Heat syndromes, but characterized by slippery diarrhea unresponsive to various medications. A woman tried hundreds of remedies without success until she was given Qian Yi’s Muxiang Wan, resulting in recovery after just a few doses. Since then, this formula has proven effective for all such cases.
Huhuanglian Wan (Picrorhiza Pill) treats Heat Gan.
Ingredients: Huhuanglian (Picrorhiza Rhizome), Huanglian (Coptis Rhizome; each 0.5 liang), Zhusha (Cinnabar, 1 fen).
Preparation: Grind the first two ingredients into fine powder, insert the Cinnabar powder into pig gallbladders, suspend the gallbladders in light fermented grain water in a clay pot, and boil for the duration of one meal. Remove, then add Lvhui (Aloe) and Shexiang (Musk; each 1 fen). Mix with rice flour to form pills the size of sesame seeds. Take 5–7 pills up to 10–20 pills per dose, washed down with Mi Yin (Rice Drink), after meals. An alternative prescription adds Hamo (Toad, 0.5 liang) without burning.
Rusheng Wan (Like-Sage Pill) treats Cold-Heat Gan (see "Gan Diarrhea" section for the formula).
Chao Yuanfang stated: When children present with a sallow face, straight hair, intermittent high fever, inability of food intake to nourish muscles and skin, and eventually death after prolonged duration, it is called Wugu Gan (Innocent Gan). Legend says there is a bird named Wugu in the sky that hides by day and roams by night, washing children's clothes and mats. After dew falls overnight, the bird flies over, takes these clothes for the child to wear and mats for the child to sleep on, causing the disease. *Taiping Shenghui Fang* records that children with Wugu Gan have a nodule behind the head like a bean, which moves when pressed. This resembles the forbidden worm under the tongue of birds and beasts. If not removed quickly, it will endanger life. Initially, the nodule is soft and painless, containing worms like rice flour. With heat, it grows larger, leading to tendon binding. Once bound, the worms disperse with Qi and Blood, multiplying and eroding viscera, causing sores on muscles, or bloody purulent diarrhea, leading to gradual emaciation, large head with erect hair, weak limbs, and early death. So-called Wugu Gan Dysentery involves abdominal distension, bloody purulent diarrhea, withered hair and skin, progressive emaciation, deficient intestines and stomach, and irregular dysentery, hence the name. Master Wang from Handong stated: The ancient claim that a bird named Wugu urinates on sun-dried children's clothes causing illness and emaciation is incorrect. This condition is actually caused by Eight Evils: hunger, fullness, fatigue, labor, wind, fright, summerheat, and accumulation. Prolonged exposure leads to emaciation, failure to gain muscle from food, nighttime crying, slight fever, thirst, lack of appetite control, or skin sores/eczema. Zhu’s *Eight-Piece Brocade Song* sings: Child’s Wugu Qi arises from maternal misconduct. If care is prudent, emaciation is avoided. Fright and thin cold cause wind diseases; warmth and cold cause Qi flaccidity. Must remove sick milk, avoid heavy clothing. Do not feed too early; speech delay is not feared. Eight prohibitions in theory: frequent weakness in chest, shiny scalp, sparse hair. Liver congestion invades eyes; Spleen yellow enters limbs. Whole body rashes, widespread sores. Unceasing diarrhea, aversion to cold with no fixed time. Cannot play with embroidered balls or bamboo horses. White halos appear in pupils, clear saliva drips from mouth. Grinding teeth biting nails, raising hands to scratch brows. Nightly eating melons/fruits, morning eating soil/mud. Stomach injury causes intestinal bloating; Lung excess causes wheezing doubtlessly. Unceasing diet, sleeping drunk-like.
Fei'er Wan (Flesh-Nourishing Pill) treats Wugu Gan in children, characterized by a bean-sized object at the back of the neck/head, movable upon pressure, soft and painless. Long-term use yields miraculous effects.
Ingredients: Huhuanglian (Picrorhiza Rhizome), Shenqu (Medicated Leaven, stir-fried), Maifu (Wheat Bran; each 5 qian), Binglang (Areca Seed, 3 qian), Muxiang (Aucklandia Root, 2 qian), Roudoukou (Nutmeg, baked in flour coating), Shijunzi Rou (Quisqualis Fruit Flesh; each 2.5 qian).
Preparation: Grind into fine powder, mix with steamed dough pills the size of millet seeds. Wash down with Rice Drink, taken far from meals.
*Taiping Shenghui Fang* Biejia San (Softshell Turtle Powder) treats pediatric Wugu Gan, characterized by a thin neck, large abdomen, and dry, erect hair resembling tufts.
Ingredients: Biejia (Softshell Turtle Shell, 3 fen, coated with vinegar, roasted yellow, remove skirt edge), Binglang (Areca Seed, 3 pieces), Chenxiang (Agarwood), Loulu (Euphrasia Root), Niubangzi (Arctium Seed, lightly stir-fried), Shijunzi (Quisqualis Fruit), Chishao Yao (Red Peony Root), Helile Pi (Terminalia Fruit Peel), Gancao (Licorice Root, roasted slightly red, cut; each 0.5 liang).
Preparation: Crush and sieve into powder. Take 1 qian per dose, decoct in one small cup of water until reduced to half a cup, strain, and take warm according to the child's age, divided into doses.
[Zhang Huan] Xiehu Dan (Gecko Pill) cuts Gan toxicity and dispels poison.
Ingredients: Gan Xiehu (Dried Gecko, male, lightly roasted, one piece), Woniu Ke (Snail Shell), Lanxiang Gen (Lysimachia Root), Dianhua (Indigo Flower; each 1 fen. Crush and sieve into fine powder, then add) Xionghuang (Realgar, water-ground and finely ground), Shexiang (Musk, finely ground; each 1 fen), Longnao (Borneol, 0.5 fen, finely ground).
Preparation: Mix thoroughly, make a paste with rice vinegar and wheat flour, form pills the size of millet seeds. Take 10 pills per dose, washed down with Sesame Decoction, after milk/meals.
Xiangjia Tang (Agarwood and Turtle Shell Decoction) cuts Gan disease and dispels evil.
Ingredients: Loulu (Euphrasia Root, 1 liang), Chenxiang (Agarwood, cut), Niubangzi (Arctium Seed, lightly stir-fried), Helile Pi (Terminalia Fruit Peel, lightly roasted), Anshixiang (Benzoin Resin), Biejia (Softshell Turtle Shell, coated with butter, roasted yellow, remove skirt edge), Ruxiang (Frankincense, ground; each 0.5 liang).
Preparation: Crush and sieve into fine powder, mix with Frankincense. Take 1 qian per dose, decoct in 0.8 cups of water with a little Ginseng, reduce to 0.4 cups, strain, and take warm, adjusting dosage based on the child's age.
[Zhang Huan] Yufen San (Jade Powder) treats Wugu Gan Dysentery, stops diarrhea and cuts Gan.
Ingredients: Hufen (Lead Carbonate, 1 liang), Bailonggu (White Dragon Bone), Shuimo Xionghuang (Water-ground Realgar; each ground and lightly roasted), Chumu Gen Baipi (Paper Mulberry Root Bark), Loulu (Euphrasia Root), Baima Yeye (White Horse Night Eye [likely a specific mineral or herb], washed and dried; each 0.5 liang).
Preparation: Crush and sieve into fine powder, mix well. Take 1 zi to 0.5 qian per dose, mixed with egg white, before milk/meals.
Er Gan Dan (Two Liver Pills) treats persistent Wugu Gan Dysentery.
Ingredients: Dichang Cao (Scrophularia Root), Changpu (Acorus Rhizome, 1 cun, 9 joints), Loulu (Euphrasia Root; each 1 liang), Huhuanglian (Picrorhiza Rhizome), Diyü (Sanguisorba Root; each 0.5 liang. Crush and sieve into fine powder, then use) Ji Gan (Chicken Liver, thinly sliced), Zhu Gan (Pig Liver, with a little salt, boiled with the above herbs until cooked; each 1 liang).
Preparation: Pound together in a stone mortar 100–200 times into a paste, form pills the size of millet seeds. Take 10 pills per dose, washed down with Musk Decoction, before meals, adjusting dosage based on the child's age.
Meirou San (Plum Flesh Powder) treats Wugu Gan with unceasing thirst and diarrhea, eye opacities, and bodily edema.
Ingredients: Wumei Rou (Dark Plum Flesh, stir-fried dry), Mian Huangqi (Astragalus Root), Gange (Kudzu Root; each 1 liang), Chuan Huanglian (Coptis Rhizome), Gualou Gen (Trichosanthes Root), Ganjiang (Dried Ginger, roasted), Gancao (Licorice Root, roasted; each 0.5 liang).
Preparation: Crush and sieve into fine powder. Take 1 qian per dose, decoct in one cup of water until reduced to 0.6 cups, strain, keep warm, and administer frequently.
Lanye Tang (Isatis Leaf Decoction) treats Wugu Gan with continuous bloody dysentery.
Ingredients: Lanye (Isatis Leaf, 1 liang), Dilong (Earthworm), Renshen (Ginseng Root, remove rhizome), Wumei Rou (Dark Plum Flesh), Donggua Ren (Winter Melon Seed), Huanglian (Coptis Rhizome), Chifuling (Red Poria, Woniu Ke (Snail Shell, lightly stir-fried; each 0.5 liang).
Preparation: Crush and sieve into fine powder. Take 1 qian per dose, decoct in one small cup of water until reduced to 0.6 cups, strain, take warm, before milk/meals.
Tianling Dan (Heavenly Spirit Pill) treats Wugu Gan with chronic dysentery not healing.
Ingredients: Tianlinggai (Skull Cap of Human Infant, one piece), Ganchan (Dried Toad, 1 liang, burned to ash), Huhuanglian (Picrorhiza Rhizome), Langdangzi (Datura Seed, washed to remove floating ones, roasted black; each 0.5 liang), Pishuang (Arsenic Trioxide, 1 fen, wrapped with Tianlinggai in wet paper and mud, roasted red-hot over charcoal, cooled. Crush and sieve into fine powder, then add) Shexiang (Musk, 1 fen).
Preparation: Mix well, form pills with soft rice the size of millet seeds. Take 5 pills per dose, washed down with breast milk, adjusting dosage based on the child's age.
Wenzang Tang (Warm Viscera Decoction) treats pediatric Wugu Gan Dysentery persisting for a long time with cold extremities.
Ingredients: Roudoukou (Nutmeg, shelled), Ganjiang (Dried Ginger, roasted; each 1 liang), Longgu (Dragon Bone), Danggui (Angelica Sinensis), Nongpou (Magnolia Bark, remove rough bark, coat with ginger juice, roast until fragrant; each 0.5 liang), Fuzi (Aconite Root, one piece, weighing 0.5 liang, roasted, remove skin and umbilicus), Maoxiang (Vetiver Root, 0.5 fen, cut).
Preparation: Crush and sieve into fine powder. Take 1 qian per dose, decoct in 0.8 cups of water with three slices of fresh ginger, reduce to 0.5 cups, strain, take warm, before milk/meals.
Pufu Dan (Magnolia and Aconite Pill) treats Wugu Gan Dysentery with mixed red and white discharge.
Ingredients: Nongpou (Magnolia Bark, coat with ginger juice, roast until fragrant), Helile Pi (Terminalia Fruit Peel, baked in flour coating; each 1 liang), Fuzi (Aconite Root, one piece, roasted, remove skin and umbilicus), Longgu (Dragon Bone), Wumei Rou (Dark Plum Flesh), Chishizhi (Red Halloysite; each 0.5 liang).
Preparation: Crush and sieve into fine powder, mix with refined honey to form pills the size of millet seeds. Take 10 pills per dose, washed down with Rice Drink, before milk/meals.
Renzhongbai San (Human Urine Deposit Powder) treats pediatric Wuggy Gan Qi, cold-heat stagnation not resolving, abdominal distension and pain.
Ingredients: Renzhongbai (Urine Deposit, 1 fen), Shexiang (Musk, 0.5 fen), Hamo (Toad, coated with butter, roasted scorched), Lvhui (Aloe; each 0.5 liang).
Preparation: Grind finely into powder. On an empty stomach and late evening, mix half a qian with warm water. After taking, foul matter should be expelled. Adjust dosage based on the child's age.
Zhusha Wan (Cinnabar Pill) treats all types of pediatric Wugu Gan, sallow emaciation, abdominal pain, or dysentery with worms; treats both cold and heat.
Ingredients: Zhusha (Cinnabar, 1 fen, finely ground. One source uses 3 fen), Changpu (Acorus Rhizome), Loulu (Euphrasia Root; each 1 liang), Xionghuang (Realgar, 1 fen, finely ground. One source uses 3 fen), Ganchan (Dried Toad, one piece, roasted in vinegar until yellow), Shexiang (Musk, 1 liang, finely ground. One source uses 1 fen, *Wanquan Fang* also uses 1 fen).
Preparation: Crush and sieve into powder, grind uniformly, mix with millet rice flour to form pills the size of sesame seeds. Dissolve 2 pills in porridge drink per dose, taken on an empty stomach and in the afternoon, adjusting dosage based on the child's age.
Juemingzi Wan (Cassia Seed Pill) treats pediatric cold-heat Wugu Gan, occasional fright-heat, nighttime crying, green-yellow-white stool, hot head and body, hair tufted like grass, yellow-emaciated limbs, poor appetite.
Ingredients: Matijuemingzi (Cassia Seed, 2 liang).
Preparation: Crush and sieve into powder, mix with refined honey to form pills the size of sesame seeds. Take 3 pills after meals with warm water, adjusting dosage based on the child's age.
Loulu San (Euphrasia Powder) treats pediatric Wugu Gan with abdominal distension or intermittent diarrhea/dysentery due to cold-heat imbalance.
Ingredients: Loulu (Euphrasia Root, 1 liang).
Preparation: Crush finely, sieve into powder. Take 1 qian of powder with 1 liang of pork liver and a little salt, boil until cooked, take on an empty stomach in one go, washed down with porridge drink.
Loulu Wan (Euphrasia Pill) treats pediatric Wugu Gan Dysentery with emaciation, loss of appetite, intra-abdominal worm movement, and frequent vomiting of clear fluid.
Ingredients: Loulu (Euphrasia Root, 2 liang), Zhu Gan (Pork Liver, dried), Chuzhu Gen Baipi (Paper Mulberry Root Bark, cut; each 1 liang).
Preparation: Crush and sieve into powder, mix with refined honey, pound 100–200 times, form pills the size of beans. Dissolve one pill in warm water per dose, take at any time, adjusting dosage based on the child's age.
*Taiping Shenghui Fang* Another Formula: Use Dizidan (Zanthoxylum Root Bark, 1 liang), crush finely, sieve into powder. Take 1 qian per dose with 1 liang of pork liver boiled with a little salt, eat at any time, adjusting dosage based on the child's age.
Formula for Persistent Pediatric Wugu Gan Dysentery:
Use Meishizi (Chebulic Myrobalan, two pieces), stir-fry until red-black, crush finely, sieve into powder. Mix with half a spoonful of flour to make cakes, bake until cooked, grind into powder. Take half a qian mixed with porridge drink at any time, adjusting dosage based on the child's age.
*Waitai Beiji* Formula for Pediatric Wugu Gan Dysentery:
Ingredients: Danggui (Angelica Sinensis), Longgu (Dragon Bone), Huanglian (Coptis Rhizome), Renshen (Ginseng Root), Meishizi (Chebulic Myrobalan), Gancao (Licorice Root, roasted; each 1 liang).
Preparation: Crush six ingredients into powder, mix with honey to form pills. Take 3 pills twice daily, stop when healed. Adjust dosage based on age/size.
*Waitai Jiuji* Treatment for Emaciated Head Dry Wugu with Dysentery:
Crush and squeeze juice from Machixian (Purslane), take 3 he, stop when healed.
*Zimu Milu* Formula for Red-White Wugu Dysentery Complicated by Gan:
Steam Hufen (Lead Carbonate) thoroughly, roast until color changes, take with drink.
*Chuanyan* Formula for Wugu Disease in Children Aged One to Two Years:
Roast and grind Yemingsha (Bat Guano) into powder, mix freely with rice and feed. For three-year-olds, it is called Dry Wugu.