气大温。味辛。无毒。主五劳七伤。风虚冷。骨髓伤败。肾冷精流。及妇人血气
堕胎。（盐水炒）
补骨脂气大温。禀天阳明之火气。入足阳明胃经。味辛无毒。得地西方之金味。入手太
阴肺
经。色黑而形如肾。入足少阴肾经。气味俱升。阳也。其主五劳七伤者。五脏之劳。食忧饮
房室饥劳经络营卫七者之伤。莫不伤损先天后天真气而成也。补骨入肾。补真阳以生土。先
天与后天相接。腐水谷而化精微。则劳者可温。而伤者可益。风虚冷者。邪风乘虚而入。以
致患冷也。其主之者。辛温可以散风祛冷也。肾主骨。骨髓伤败。肾虚寒也。肾既虚寒。则
气不足摄精。精自流矣。补骨温益阳气。辛能润髓。所以主之。妇人血气。妇人血冷气寒也
。补骨温肺。肺主气。而为津液之化源。所以治血冷气寒也。胎者大气举之也。补骨辛温。
温能活血。辛能散气。气血活散。所以堕胎也。
制 方
补骨脂四两。菟丝子四两。核桃肉一两。沉香、乳香、没药各二钱半丸。治下元虚败。
同
黑
芝麻丸。治五劳七伤。同杜仲、核桃肉。名青娥丸。治腰痛。同白茯、没药、酒丸。名返精
丸。治心肾不交。同青盐末。治精气不固。同小茴香酒丸。治小便无度。同韭子末。治玉茎
不痿。同肉蔻丸。名二神丸。治虚泄。同粟壳。治久痢不止。
【补骨脂】
气味大温。味辛。无毒。主治五劳七伤（泛指多种慢性虚损性疾病）、风邪导致的虚冷证、骨髓损伤败坏、肾脏寒冷导致精液滑脱，以及妇女气血虚弱导致的堕胎。（需用盐水炒制）
补骨脂气性大温，禀受天地阳明经的火气，入足阳明胃经；味辛且无毒，得地西方金的滋味，入手太阴肺经；颜色黑且形状像肾，入足少阴肾经。其气味都主升，属于阳。它主治五劳七伤的机理是：五脏的劳损，以及因饮食、忧愁、饮酒、房事、饥饿、劳累、经络营卫失调这七种因素造成的损伤，无不损伤先天和后天之本的真气。补骨脂能补肾，通过补充真阳来生助脾土（火生土），使先天与后天相互衔接，腐熟水谷并转化为精微物质，那么劳损者可以得到温养，受伤者可以得到补益。所谓风虚冷证，是指邪风乘虚而入，从而导致患冷症。补骨脂之所以能主治此症，是因为其辛温之性能疏散风邪、祛除寒冷。肾主骨，骨髓损伤败坏，是因为肾虚寒所致。肾脏既已虚寒，则气不足以固摄精液，精液就会自行流出。补骨脂能温补阳气，辛味又能润髓，所以能主治此症。所谓妇人血气病，是指妇女血冷气寒。补骨脂能温肺，肺主气，且为津液生成的源头，所以能治疗血冷气寒之症。胎儿是靠大气举托的。补骨脂辛温，温能活血，辛能散气，气血流通发散，所以会导致堕胎。
【制剂方】
补骨脂四两，菟丝子四两，核桃肉一两，沉香、乳香、没药各二钱半，研末泛丸。主治下元虚败（肾阳不足，元气亏损）。
与黑芝麻同用制成丸剂，主治五劳七伤。
与杜仲、核桃肉同用，名为青娥丸，主治腰痛。
与白茯苓、没药同用，酒泛为丸，名为返精丸，主治心肾不交。
与青盐末同用，主治精气不固。
与小茴香同用，酒泛为丸，主治小便频数无度。
与韭菜子末同用，主治阴茎勃起功能障碍（玉茎不痿）。
与肉豆蔻同用制成丸剂，名为二神丸，主治虚寒泄泻。
与罂粟壳同用，主治久痢不止。
[Bu Gu Zhi] (Psoraleae Fructus)
The Qi is greatly warm. The taste is pungent. It is non-toxic. It primarily treats Wu Lao Qi Shang (five labors and seven injuries, referring to various chronic deficiency syndromes), wind-induced deficiency-cold, bone marrow injury and degeneration, kidney cold with seminal emission, and spontaneous abortion due to blood and qi deficiency in women. (Processed with salt water.)
Bu Gu Zhi has a greatly warm Qi, inheriting the fire Qi of the Heavenly Yangming channels. It enters the Foot-Yangming Stomach Channel. Its taste is pungent and non-toxic, obtaining the metal flavor of the Earthly West. It enters the Hand-Taiyin Lung Channel. Its color is black and its shape resembles the kidney, so it enters the Foot-Shaoyin Kidney Channel. Both its Qi and taste are ascending, which belongs to Yang. The reason it treats Wu Lao Qi Shang is that the labor of the five zang organs, as well as the injuries caused by the seven factors—diet, worry, drinking, sexual intercourse, hunger, fatigue, and disorders of the meridians, Ying, and Wei—damage the True Qi of both the Pre-Heaven (Innate) and Post-Heaven (Acquired) foundations. Bu Gu Zhi tonifies the kidney, supplementing True Yang to generate Earth (Fire generates Earth), connecting the Pre-Heaven and Post-Heaven. This allows for the rotting and cooking of food and fluids into essence and subtle nutrients, thereby warming those who are labored and benefiting those who are injured. Regarding wind-deficiency-cold, pathogenic wind enters due to deficiency, resulting in cold syndromes. It treats this because its pungent-warm nature can disperse wind and dispel cold. The Kidney governs bones; bone marrow injury and degeneration are due to Kidney deficiency and cold. Since the Kidney is deficient and cold, Qi is insufficient to secure the essence, leading to spontaneous seminal emission. Bu Gu Zhi warms and benefits Yang Qi, and its pungency can moisten the marrow, thus treating these conditions. Regarding women's blood and Qi disorders, this refers to blood deficiency and cold Qi in women. Bu Gu Zhi warms the Lung; the Lung governs Qi and serves as the source of transformation for body fluids, thus treating blood deficiency and cold Qi. The fetus is held up by the Great Qi. Bu Gu Zhi is pungent and warm; warmth can invigorate blood, and pungency can disperse Qi. When blood and Qi circulate and disperse freely, it leads to spontaneous abortion.
[Preparation Formulas]
Bu Gu Zhi (4 liang), Tu Si Zi (4 liang), He Tao Rou (1 liang), Chen Xiang, Ru Xiang, and Mo Yao (each 2 qian 5 fen), processed into pills. Treats deficiency and degeneration of the Lower Yuan (Kidney Yang deficiency and depletion of primal Qi).
Combined with Hei Zhi Ma (black sesame) into pills: treats Wu Lao Qi Shang.
Combined with Du Zhong and He Tao Rou, named Qing E Wan: treats lower back pain.
Combined with Bai Fu Ling and Mo Yao, wine-coated into pills, named Fan Jing Wan: treats Heart-Kidney non-interaction.
Combined with Qing Yan (green salt) powder: treats insecurity of essence and Qi.
Combined with Xiao Hui Xiang, wine-coated into pills: treats excessive frequency of urination.
Combined with Jiu Zi (leek seed) powder: treats impotence.
Combined with Rou Dou Kou into pills, named Er Shen Wan: treats deficiency-cold diarrhea.
Combined with Su Ke (poppy shell): treats persistent dysentery that does not cease.