《全婴方》小儿每早食后发热，夜则凉，世医多谓虚劳，或为疳热，不知此血热
证也，宜龙胆丸、地黄膏、之类，时时与服节瘥。
接∶《全婴方》所云血热者，巳午发热，遇夜则凉，与东垣所谓夜则发热，昼
则明了，不同，然东垣所云血热者，指阴虚而生内热也，夜则发热，昼则明了，
取其昼阳夜阴也，郑氏所云血热者，指小儿血盛实而言也，盖谓巳午者，心火用
事之时也，心主血，血气行至巳午，则阳气盛，阳气与正气相搏，故至期而发热，
非其时者，非血热也。
〔薛〕一小儿寅卯时发热，或兼搐有痰。服抱龙、泻青、二丸而愈。后复患，服
前药兼咳嗽气喘，不时发搐，面赤色，或青黄，或浮肿，或流涎。予谓咳嗽气喘脾
肺气虚也，不时发搐肝木乘脾也，面青黄肝入心脾也，浮肿流涎脾气虚也。用益智
丸以养心血，补中益气汤以补脾气而愈。一小儿巳午时发热惊悸，发时形气倦怠，
面黄懒食，流涎饮汤。予谓心气不足所致。不信，反服凉心之药，更加吐泻，睡而
露睛，手足并冷，几至慢脾风。先用六君姜桂汤佐以地黄丸而愈。一小儿申酉时发
热面赤，腹中作痛，或用峻利之剂下之，致发搐吐痰，作渴腹痛，按之即止。此脾
胃伤而变证也。用七味白术散、补中益气汤顿安。
龙胆丸 治小儿食后多发热，或夜则凉，此血热证。疳热皆可治。
宣黄连（去毛） 赤芍药（各半两） 草龙胆（去苗） 青皮（去穣。各二钱半） 槟榔（一个大者）
麝香（少许）
上为末。猪胆汁少入面糊为丸，萝卜子大。每三、二十丸，米饮，空心服。
六合汤 治小儿血热，每日巳午间发热，遇夜则凉。
当归 大黄 川芎 熟地黄
上为末。三岁一钱，水半盏，煎至三分，无时服。
猪胆丸 治小儿每日早饭后发热，夜则身凉，此血热也。
胡黄连（二钱半） 宣黄连 赤芍药（各半两）
上为末，猪胆汁和成剂，入在胆中悬，用浆水煮熟，取出，饭为丸，如豆大。
三岁三十丸，米汤送下，日三服，无时。
《全婴方》记载：小儿每天早晨进食后出现发热，到了夜晚体温则恢复正常（凉爽），世俗医生大多将其诊断为虚劳病，或者认为是疳积发热，却不知道这实际上是血热证。适宜使用龙胆丸、地黄膏等药物，经常给予服用，病情即可逐渐痊愈。
按语：《全婴方》中所说的“血热”，表现为巳时、午时（上午9点至下午3点）发热，遇到夜晚则凉爽；这与李东垣所说的“夜间发热，白天清醒”是不同的。然而，李东垣所说的“血热”，指的是阴虚而生内热，即夜间发热、白天清醒，这是取法于昼属阳、夜属阴的理论。郑氏所说的“血热”，是指小儿气血充盛且实邪内蕴而言。大概所谓“巳午时”，是心火当令的时候，心主血脉，气血运行至巳午之时，阳气旺盛，阳气与正气相互搏结，所以在该时段出现发热；如果不是在该时段发热，就不属于血热证。
〔薛己〕有一个小儿在寅时、卯时（凌晨3点至7点）发热，有时兼有抽搐和痰多症状。服用抱龙丸、泻青丸两种药丸后痊愈。后来再次患病，服用前两种药丸的同时伴有咳嗽气喘，不时发生抽搐，面色发红，或呈青色、黄色，或面部浮肿，或流口水。我认为咳嗽气喘是由于脾肺气虚所致；不时抽搐是因为肝木乘袭脾土；面色青黄是因为肝气传入心和脾；浮肿流涎是因为脾气虚弱。于是使用益智丸来滋养心血，使用补中益气汤来补益脾气，从而治愈。另一个小儿在巳时、午时发热并伴有心惊悸动，发作时形体和精神倦怠，面色发黄，食欲不振，流口水，想喝热水。我认为这是由于心气不足引起的。家属不信，反而服用清心凉药，导致更加严重的呕吐腹泻，睡觉时眼睛半睁（露睛），手脚冰凉，几乎发展成慢脾风。先用六君姜桂汤配合地黄丸治疗而痊愈。还有一个小儿在申时、酉时（下午3点至7点）发热且面色发红，腹部疼痛，有人用峻猛的泻下剂攻下，导致出现抽搐、吐痰、口渴腹痛，按压腹部疼痛就停止。这是脾胃受损而产生的变证。使用七味白术散、补中益气汤迅速使病情安定。
龙胆丸：治疗小儿进食后容易发热，或者夜间身体凉爽，这是血热证。疳积发热也都可以治疗。
药材组成：宣黄连（去毛）、赤芍药（各半两）；草龙胆（去苗）、青皮（去瓤，各二钱半）；槟榔（一个大者）；麝香（少许）。
制法用法：以上药物研为细末。加入少量猪胆汁和面糊制成丸药，大小如萝卜子。每次服用三二十丸，米汤送服，空腹服用。
六合汤：治疗小儿血热，每天巳时、午间发热，遇到夜晚则凉爽。
药材组成：当归、大黄、川芎、熟地黄。
制法用法：以上药物研为细末。三岁儿童服用一钱，加水半盏，煎煮至剩余三分，不拘时候服用。
猪胆丸：治疗小儿每天早饭后发热，夜间身体凉爽，这是血热证。
药材组成：胡黄连（二钱半）、宣黄连、赤芍药（各半两）。
制法用法：以上药物研为细末，用猪胆汁调和成剂状，放入猪胆中悬挂起来，用浆水煮熟，取出后以米饭为黏合剂制成丸药，大小如豆粒。三岁儿童服用三十丸，米汤送下，每日三次，不拘时候。
Quan Ying Fang records: When infants and young children experience fever after eating in the morning every day, but their body temperature returns to normal (cool) at night, worldly physicians mostly diagnose it as deficiency consumption (Xu Lao), or consider it to be malnutrition fever (Gan Re). They do not realize that this is actually a pattern of Blood Heat. It is appropriate to use Long Dan Wan (Gentian Pill) and Di Huang Gao (Rehmannia Paste) and similar formulas, administering them frequently until the condition gradually resolves.
Commentary: The "Blood Heat" mentioned in Quan Ying Fang refers to fever during the Si and Wu hours (9:00 AM – 3:00 PM), with cooling occurring at night. This differs from Li Dongyuan's description of "fever at night and clarity during the day." However, Li Dongyuan's concept of "Blood Heat" refers to internal heat generated by Yin deficiency, characterized by fever at night and clarity during the day, based on the theory that day belongs to Yang and night belongs to Yin. Zheng's concept of "Blood Heat" refers to the condition where an infant's blood and Qi are abundant and excess pathogens are present internally. Specifically, the "Si and Wu hours" are when Heart Fire is dominant. Since the Heart governs Blood, when Qi and Blood circulate to the Si and Wu periods, Yang Qi becomes vigorous. The struggle between Yang Qi and Healthy Qi causes fever during these specific times; if fever occurs outside these times, it does not constitute Blood Heat.
[Xue Ji] A child experienced fever during the Yin and Mao hours (3:00 AM – 7:00 AM), sometimes accompanied by convulsions and phlegm. The condition resolved after taking Bao Long Wan (Protect Dragon Pill) and Xie Qing Wan (Drain Green Pill). Later, the illness recurred. While taking the previous two pills, the child developed coughing and wheezing, frequent convulsions, a red complexion, or complexions of green/yellow, facial edema, or salivation. I reasoned that coughing and wheezing were due to Spleen and Lung Qi deficiency; frequent convulsions were due to Liver Wood overacting on the Spleen; the green-yellow complexion indicated Liver Qi affecting the Heart and Spleen; edema and salivation indicated Spleen Qi deficiency. Therefore, I used Yi Zhi Wan (Yi Zhi Pill) to nourish Heart Blood, and Bu Zhong Yi Qi Tang (Tonify the Middle and Augment the Qi Decoction) to tonify Spleen Qi, resulting in recovery. Another child experienced fever and palpitations during the Si and Wu hours. During episodes, the child appeared physically and mentally fatigued, had a sallow complexion, poor appetite, salivation, and a desire to drink hot water. I attributed this to insufficient Heart Qi. The family disagreed and instead administered Heart-cooling medicines, which worsened the condition with vomiting and diarrhea, sleeping with eyes partially open (exposed pupils), and cold extremities, nearly developing into Slow Spasm Wind (Man Pi Feng). I first treated with Liu Jun Jiang Gui Tang (Six Gentlemen Decoction with Ginger and Cinnamon) assisted by Di Huang Wan (Rehmannia Pill), leading to recovery. Another child experienced fever and a red face during the Shen and You hours (3:00 PM – 7:00 PM), accompanied by abdominal pain. Someone used harsh purgatives to drain the bowels, causing convulsions, phlegm expectoration, thirst, and abdominal pain that ceased upon pressure. This was a complication arising from damage to the Spleen and Stomach. Administration of Qi Wei Bai Zhu San (Seven-Ingredient Atractylodes Macrocephala Powder) and Bu Zhong Yi Qi Tang quickly stabilized the condition.
Long Dan Wan: Treats infants and young children who easily develop fever after eating, or feel cool at night, indicating a Blood Heat pattern. It can also treat Malnutrition Fever (Gan Re).
Ingredients: Xuan Huang Lian (Scutellariae Radix, de-haired), Chi Shao Yao (Paeoniae Radix Rubra) (each 1.5 liang); Cao Long Dan (Gentianae Radix, de-rooted), Qing Pi (Citri Reticulatae Pericarpium Viride, de-pith) (each 0.83 liang); Bing Lang (Arecae Semen, one large fruit); She Xiang (Moschus) (a small amount).
Preparation and Administration: Grind the above ingredients into fine powder. Add a small amount of Pig Bile and rice paste to form pills, sized like radish seeds. Administer 3–20 pills per dose, taken with rice drink on an empty stomach.
Liu He Tang: Treats Blood Heat in infants and young children, characterized by fever daily during the Si and Wu hours, with cooling at night.
Ingredients: Dang Gui (Angelicae Sinensis Radix), Da Huang (Rhei Radix et Rhizoma), Chuan Xiong (Chuanxiong Rhizoma), Shu Di Huang (Rehmanniae Radix Praeparata).
Preparation and Administration: Grind the above ingredients into fine powder. For a three-year-old child, administer 1 qian, decoct with half a zhan of water until one-third remains. Take at any time.
Zhu Dan Wan: Treats infants and young children who develop fever after breakfast daily and feel cool at night, indicating Blood Heat.
Ingredients: Hu Huang Lian (Coptidis Rhizoma / Scutellariae Radix variant, 0.83 liang), Xuan Huang Lian, Chi Shao Yao (each 1.5 liang).
Preparation and Administration: Grind the above ingredients into fine powder. Mix with Pig Bile to form a paste, place inside a pig gallbladder, suspend it, and cook thoroughly using Jiang Shui (fermented rice liquid). Remove, mix with rice flour to form pills, sized like beans. For a three-year-old child, administer 30 pills with rice soup, three times daily, at any time.