附子生用则性奔窜而有毒。熟用则质温润而无毒。其大重一两三四钱以上。团坐平顶。
旁无
多角者。方称附子。性主沉补命门真火。其小仅一两以下者。或挺尖。或歪侧。或两脐。或
多角。皆为川乌。性主驱风逐寒。走散经络。而非熟附子温补之比也。若附子制以姜汁。与
干姜生姜同用。则为姜附汤主治足三阴驱散上下表里经络脏腑之客寒为要药。其疗真阳虚脱
则当用童便制者。君以人参。其姜汁制者不可混用也盖姜桂附子。同为大热。第姜性兼辛。
主发散而桂味甘而辛。可升可降。若熟附则质重性沉。主下行。所以不同也。若阳脱而误用
姜。令阳愈脱矣。何以言之。立斋曰先兄体貌丰伟。唾痰甚多。脉洪有力。殊不耐劳。遇风
头晕欲仆。口舌欲裂。或至赤烂。误食姜蒜少许。口疮益甚。服八味丸。及补中益气汤。加
附子钱许即愈。停药月余。诸症仍作此命门虚火不归元也据此则姜附虽均称热药。何可混施
乎。虞搏曰附子禀雄壮之质。有斩关夺门之功。能引补气药行十二经。以追复散失之元阳引补
血药入血分以滋养不足之真阴引发散药开腠理以驱逐在表之风寒引温暖药达下焦以祛除在里
之冷湿吴绶曰附子乃阴症要药凡伤寒传变三阴。及中寒夹阴。虽身大热而脉沉者必用之。或
厥冷腹痛。脉沉细。甚则唇青囊缩者急须用之。有退阴回阳之力起死回生之功近世阴症伤寒
往往疑似不敢用附子。直待阴极阳竭而后用之。已迟矣。且夹阴伤寒。内外皆阴。是阳气顿
衰。必须急用人参健脉以益其原佐以附子温经散
寒。舍此不用。将何以救之。王氏究原方云凡用桂附药。并宜冷服者。热因寒用也。盖阴寒
在下。虚阳上浮。治之以寒。则阴气益甚而病增。治之以热。则拒格而不纳热药冷冻饮料。下嗌
之后。冷体既消。热性便发。而病气随愈不违其情而致大益此反治之道也昔仲景治寒疝内结
。用蜜煎乌头。近效方治喉痹用蜜煎附子含之咽汁。丹溪治疝气。用乌头栀子并热因寒用也
。
东垣治冯翰林侄阴盛格阳伤寒。目赤烦渴引饮。脉来七八至。但按之则散。用姜附汤。加人
参投半斤服之。得汗而愈。此神圣之妙也。考昔荆府都昌王体瘦而冷。无他病。日以附子煎
汤饮兼嚼硫黄。如此数岁。蕲州卫张百户。平生服鹿茸附子药。至八十余康健倍常。宋张杲
医说载赵知府耽酒色。每日煎干姜熟附汤。吞硫黄金液丹百粒。乃能健啖。否则倦弱不支寿
至九十。他人服一粒即为害。此数人者皆其脏腑赋禀之偏。服之有益无害。不可以常理论也
愚以为此药唯阴藏者宜之若阳藏而误用受祸极速也凡用桂附须君以人参少佐甘草。或大枣则
无毒。仲景八味丸亦为阴火不足者设故阳盛假寒不宜妄用也桂性甘辛大热能宣导百药。通血
脉。有汗能止。无汗能出。桂枝主上行而散。肉桂主下行而补驱风理寒。定烦解渴。与附子
同补命门真火。专益脾胃之母。亦善利水通淋。止虚脱。破淤血。功能不可尽阐又治喉痹失
音
。阳虚失血。内托痈疽痘疮。九种心痛胁疼 疟奔豚疝气利肺抑肝冷痰霍乱喘胀诸症。李濒
湖曰麻黄遍彻皮毛。故专于发汗而散寒邪肺主皮毛辛走肺也桂枝透达营卫故能解肌而风邪除
脾主营肺主卫甘走脾辛走肺也肉桂下行益火之源。此东垣所谓肾苦燥急食辛以润之开腠理致
精液通其气者也又医余录云有人患赤眼肿痛。脾虚不能饮食。肝脉愈盛。但于温平药中。倍
加肉桂。杀肝而益脾。故一治两得。经云木得桂而枯是也是桂又通治寒热虚实内外上下而配
合得宜随试随效者也窃谓桂附乃斩关夺门之将。非良师莫敢轻用。然立斋每用此以救真火不
足及虚阳假热之病。叠奏殊效。非时师所能方物也。盖立斋治法。则归本命门者也。东垣则
专主脾胃者也。河涧丹溪。则专主相火湿热者也。子和则专主攻击者也节斋隐君则专主攻痰
泻
火者也。仲景则专主外感者也。法有偏擅。医当全识。若疗命门则用立斋。治脾胃则用东垣
。清湿热则用刘朱。习攻击则用子和。蠲实痰则用二
王。至伤寒虽宗长沙。而三阴主治参术归附。率多救里。则又不专于外感也若用诸子而不为
诸子所用机权在我法从人施一人而兼众人之用众人而资一人之识斯得矣至立斋先生则又集诸
家之大成。发前人所未发。开将来之聋聩者也。奈何时师视桂附如蛇蝎应用不用。卒至误人
于死。盖亦因丹溪谓附子无人表其害人之祸。故致有泥成说而坐失机宜者。虽然使用非所当
。即参 亦能为害。何独桂附乎。医学纲目有云黄 能助三焦之火人参能补诸经之阳。白术
能长五脏之气。此三者皆上药。是在人体悟而无失其气宜可也。余因续之曰桂附能救阴阳之
脱。
附子若生用,则药性猛烈窜行且有毒;若经炮制熟用,则质地温润而无毒。其中重量在一两、三两或四钱以上的,形状圆润坐底、顶部平坦,旁边没有多余棱角分叉的,才配称为“附子”。其药性主沉降,能补益命门真火。那些重量仅在一两以下的,或者形状挺尖、歪斜偏侧、有两个脐眼、或多有棱角的,都称为“川乌”。川乌的药性主驱散风邪、驱逐寒邪,走窜发散于经络之中,这与熟附子的温补作用不可相提并论。
如果将附子用姜汁炮制,并与干姜、生姜同用,就构成了“姜附汤”,它是治疗足三阴经(肝、脾、肾经)驱散上下、表里、经络、脏腑间客居寒邪的要药。若要治疗真阳虚脱之证,则应当使用童便(童子尿)炮制的附子,并以人参为君药。此时绝不可混用姜汁炮制的附子。
大抵而言,干姜、肉桂、附子均为大热之药。但干姜的药性兼有辛味,主发散;肉桂味甘而辛,作用可升可降;而熟附子质地沉重,药性沉降,主下行。这就是它们的不同之处。若是阳气外脱之证,误用干姜,会导致阳气更加耗散脱失。为什么这样说呢?薛立斋曾说:我的兄长体态丰满伟岸,唾痰非常多,脉象洪大有力,特别不耐劳累,遇到风就头晕欲倒,口舌干燥甚至开裂,有时发红溃烂。他误食了少许姜蒜,导致口疮更加严重。后来服用八味丸,并在补中益气汤中加入约一钱的附子,病即痊愈。停药月余后,各种症状再次发作。这是命门虚火不能归元所致。据此可知,虽然姜和附子都被称为热药,但怎能混用呢?
虞搏说:附子禀赋雄壮之质,有斩关夺门的功效。它能引导补气药运行于十二经脉,以追回复散失的元阳;引导补血药进入血分,以滋养不足的真阴;引导发散药打开腠理,以驱逐在表的风寒;引导温暖药到达下焦,以祛除在里的冷湿。
吴绶说:附子是治疗阴症的要药。凡是伤寒传变至三阴经,以及中寒夹阴之证,即使身体大热但脉象沉伏的,必须使用它。如果出现四肢厥冷、腹痛、脉象沉细,甚至嘴唇发青、阴囊收缩的情况,急需使用它。附子具有退阴回阳、起死回生的功效。近代人对于阴症伤寒往往因疑似而不敢使用附子,直到阴极阳竭时才使用,那就太迟了。况且夹阴伤寒,内外皆属阴证,是阳气突然衰微,必须紧急用人参健旺脉气以益其本源,佐以附子温经散寒。除了这种方法不用,还有什么可以救治呢?
王好古考究原方指出:凡是用桂枝、附子的药物,都适宜冷服,这叫作“热因寒用”。因为阴寒在下,虚阳上浮。如果用寒凉药治疗,阴气会更盛而病情加重;如果用温热药治疗,又会被格拒而不纳受。采用冷冻饮料的方式送服热药,咽下之后,冷体消散,热性随即发挥,从而疾病随之痊愈。这不违背病情表象而能达到巨大的疗效,这就是反治之道。
过去张仲景治疗寒疝内结,用蜜煎乌头;《近效方》治疗喉痹,用蜜煎附子含化咽汁;朱丹溪治疗疝气,也用乌头、栀子,这些都是“热因寒用”的方法。
李东垣治疗冯翰林侄子的阴盛格阳伤寒,症见目赤、烦躁口渴引饮,脉搏急促七八次跳动一次,但重按则散乱无力。他用姜附汤,加入人参,投药半斤服用,患者出汗后痊愈。这真是神圣般的妙手。
考察过往案例:荆府都昌王身体瘦弱且怕冷,无其他疾病,每天饮用附子煎汤并咀嚼硫黄,如此持续数年。蕲州卫张百户,平生服用鹿茸、附子等药,到了八十多岁依然健康胜过常人。宋代张杲《医说》记载赵知府沉迷酒色,每天煎煮干姜、熟附汤,吞服金液丹一百粒,才能食欲旺盛,否则疲倦虚弱无法支撑,最终寿至九十岁。其他人服用一粒这类药物就会受害。这几个人都是因为脏腑禀赋偏颇,服用这些药物有益无害,不能用常理来衡量。
我认为这些药物只适合阴脏体质的人使用。如果是阳脏体质而误用,遭受祸害的速度极快。凡是用桂枝、附子,必须以人参为君药,少佐甘草或大枣,这样就没有毒性。张仲景的八味丸也是为阴火不足者设立的,所以阳盛假寒者不宜妄用。
桂枝药性甘辛大热,能宣导百药,通血脉,有汗时能止汗,无汗时能发汗。桂枝主上行而发散,肉桂主下行而补益,能驱风理寒,定烦解渴。与附子同用可补益命门真火,专门补益脾胃之母(肾),也善于利水通淋,止虚脱,破淤血,功能不可穷尽。此外还能治疗喉痹失音、阳虚失血、内托痈疽痘疮、九种心痛、胁痛、疟疾、奔豚、疝气、利肺抑肝、冷痰、霍乱、喘胀等各种病症。
李时珍说:麻黄遍彻皮毛,故专于发汗以散寒邪,因为肺主皮毛,辛味入肺。桂枝透达营卫,故能解肌使风邪除,因为脾主营,肺主卫,甘味入脾,辛味入肺。肉桂下行,益火之源,这正是李东垣所说的“肾苦燥,急食辛以润之”,通过开腠理、致精液、通其气来实现。
又有《医余录》记载:有人患赤眼肿痛,脾虚不能饮食,肝脉愈盛。只在温平药中倍加肉桂,以此杀肝气而益脾气,故一举两得。《内经》说“木得桂而枯”,说的就是这个道理。因此,肉桂又能通治寒热虚实、内外上下之证,只要配合得当,随试随效。
我私下认为,桂附乃是斩关夺门的猛将,若非良师高手,不敢轻易使用。然而薛立斋每每用此法救治真火不足及虚阳假热之病,屡奏奇效,这不是普通医生所能比拟的。大概薛立斋的治法,是以归藏命门为主;李东垣则专主脾胃;刘河间、朱丹溪则专主相火湿热;张子和则专主攻邪;节斋隐君则专主攻痰泻火;张仲景则专主外感。治疗方法各有偏擅,医生应当全面认识。若治疗命门病则用薛立斋之法,治疗脾胃病则用李东垣之法,清湿热则用刘朱之法,习攻邪则用张子和之法,蠲实痰则用二王之法。至于伤寒,虽尊崇长沙张仲景,但在三阴病的治疗上,多用参、术、当归、附子,大多用于救里,这就又不单纯局限于外感了。若能运用诸家之长而不被诸家所局限,机权在我,法从人施,一人兼众人之用,众人资一人之识,这才是高明的境界。至于薛立斋先生,更是集诸家之大成,发前人所未发,开启将来之蒙昧。
奈何当时的医生视桂附如蛇蝎,该用不用,最终导致误人性命。这也因为朱丹溪曾谓附子无人表其害人之祸,致使人们拘泥于成说而坐失良机。虽然如此,如果使用不当,即使是人参也能造成危害,又何独桂附呢?《医学纲目》中说:黄芪能助三焦之火,人参能补诸经之阳,白术能长五脏之气。这三者都是上药,关键在于人体悟其气宜,不使其失误即可。我因此续写道:桂附能救阴阳之脱。
If used raw, Fuzi (Prepared Aconiti Lateralis Radix) has a fierce and erratic nature and is toxic. If processed and cooked, it becomes mild in quality and non-toxic. Those weighing over one tael, three taels, or four qian, which are round at the base with a flat top and lack extra angular projections on the sides, qualify as "Fuzi". Its nature is primarily sinking and tonifying, targeting the True Fire of the Mingmen (Gate of Life). Those weighing less than one tael, or those that are pointed, skewed, have two navel-like depressions, or possess multiple angles, are all called "Chuanwu" (Sichuan Aconite Root). Chuanwu's nature is to dispel wind and drive out cold, moving and dispersing through the meridians, which cannot be compared to the warming and tonifying effects of cooked Fuzi.
If Fuzi is processed with ginger juice and used together with Ganjiang (Dried Ginger) and Shengjiang (Fresh Ginger), it constitutes the Jiangfu Tang (Ginger and Aconite Decoction), which is a crucial medicine for driving off invading cold from the Taiyin, Shaoyin, and Jueyin meridians (Foot Three Yin), as well as from the interior and exterior, meridians, and zang-fu organs. For treating the collapse of True Yang, one should use Fuzi processed with tongbian (child's urine), using Renshen (Ginseng Root) as the sovereign herb. In such cases, Fuzi processed with ginger juice must not be mixed in.
Generally speaking, Ganjiang, Rougui (Cinnamon Bark), and Fuzi are all strongly hot herbs. However, Ganjiang possesses a pungent nature and primarily promotes dispersion; Rougui is sweet and pungent, capable of ascending and descending; whereas cooked Fuzi is heavy in quality and sinking in nature, primarily directing downwards. This is their difference. If Yang collapses and Ganjiang is mistakenly used, it will cause further loss of Yang. Why is this so? Xue Lizhai said: My elder brother had a robust and imposing physique, produced excessive phlegm-saliva, had a surging and forceful pulse, and was particularly intolerant of labor. Upon exposure to wind, he would feel dizzy and nearly faint, his mouth and tongue would become dry and crack, sometimes turning red and ulcerating. He mistakenly consumed a small amount of ginger and garlic, worsening his mouth ulcers. Later, he took Bawei Wan (Eight-Ingredient Pill with Rehmannia) and Buzhong Yiqi Tang (Tonify the Middle and Augment the Qi Decoction) with approximately one qian of Fuzi added, after which he recovered. After stopping medication for over a month, all symptoms recurred. This indicates that the deficient fire of the Mingmen failed to return to its source. Based on this, although both ginger and Fuzi are termed hot medicines, how can they be used interchangeably?
Yu Bo stated: Fuzi possesses a heroic and vigorous quality, having the merit of breaking through gates and seizing doors. It can guide Qi-tonifying herbs to circulate through the Twelve Meridians to recover scattered Yuan Yang; guide Blood-nourishing herbs into the Blood level to nourish insufficient True Yin; guide dispersing herbs to open the couli (pores) to expel wind-cold at the exterior; and guide warming herbs to reach the Lower Jiao to remove internal cold-dampness.
Wu Shou stated: Fuzi is a key herb for treating Yin syndromes. Whenever Cold Damage transmits to the Three Yin meridians, or in cases of Cold damage with Yin involvement, even if the body is very hot but the pulse is deep, it must be used. If there are cold extremities, abdominal pain, a deep and fine pulse, or even cyanotic lips and retracted scrotum, it must be used urgently. Fuzi has the power to retreat Yin and restore Yang, bringing the dying back to life. In recent times, people often hesitate to use Fuzi for Yin-type Cold Damage due to suspicion, waiting until Yin is extreme and Yang is exhausted before using it, which is already too late. Moreover, in Cold Damage with Yin involvement, both interior and exterior are Yin, indicating a sudden decline of Yang. One must urgently use Renshen to strengthen the pulses and benefit the source, assisted by Fuzi to warm the meridians and disperse cold. Without this method, what else could save them?
Wang Haogu examined the original formulas and stated: When using Guizhi (Cinnamon Twig) or Fuzi, it is advisable to take them cold. This is called "treating heat with cold" (using hot herbs administered cold). Because Yin-cold is below and deficient Yang floats upward. If treated with cold herbs, Yin qi will increase and the disease worsen. If treated with hot herbs, they may be rejected and not absorbed. By administering hot medicinal decoctions as cold drinks, after swallowing, the cold nature dissipates, and the hot nature activates, causing the disease to heal. This does not violate the condition's appearance but achieves great benefit; this is the way of counter-treatment.
In the past, Zhang Zhongjing treated cold hernia with internal binding using honey-fried Wutou (Aconite Root); the *Jin Xiao Fang* treated throat bi (sore throat/swelling) using honey-fried Fuzi held in the mouth to swallow the juice; Zhu Danxi treated hernia qi using Wutou and Zhizi (Gardenia Fruit), all employing the method of "treating heat with cold."
Li Dongyuan treated the nephew of Hanlin Feng for Yin-excess blocking Yang Cold Damage, presenting with red eyes, irritability, thirst with desire to drink, and a rapid pulse beating seven or eight times per breath but scattering upon pressure. He prescribed Jiangfu Tang with added Renshen, administering half a jin (approx. 500g), after which the patient sweated and recovered. This was truly a divine miracle.
Examining past records: The Prince Duchang of Jing Prefecture was thin and cold, with no other illness. He drank Fuzi decoction daily and chewed sulfur, continuing this for several years. Zhang Baihu of Qizhou Garrison took Luzhrou (Deer Antler) and Fuzi throughout his life, remaining healthier than usual until over eighty years old. Song Dynasty's Zhang Gao's *Yi Shuo* records that Prefect Zhao, indulgent in wine and sex, boiled Ganjiang and Shufu (Processed Fuzi) daily, swallowing one hundred pills of Jin Ye Dan (Golden Liquid Pill), only then maintaining a good appetite; otherwise, he was weak and unsupported. He lived to ninety. Others who took one pill suffered harm. These individuals had biased organ constitutions; taking these herbs benefited them without harm, and cannot be judged by ordinary standards.
I believe these herbs are suitable only for those with Yin-predominant constitutions. If used mistakenly by those with Yang-predominant constitutions, disaster strikes quickly. Whenever using Guizhi or Fuzi, one must use Renshen as the sovereign herb, with a small adjunct of Gancao (Licorice Root) or Dazao (Jujube), rendering them non-toxic. Zhang Zhongjing's Bawei Wan was also designed for those with insufficient Yin-fire; thus, those with Yang-excess and false cold should not use it recklessly.
Guizhi is sweet, pungent, and greatly hot; it can disseminate and guide various herbs, unblock blood vessels, stop sweating when present, and induce sweating when absent. Guizhi primarily ascends and disperses; Rougui primarily descends and tonifies, dispelling wind and regulating cold, calming irritability and relieving thirst. Together with Fuzi, it tonifies the True Fire of the Mingmen, specifically benefiting the mother of the Spleen and Stomach (Kidney). It is also effective in promoting urination and unblocking strangury, stopping collapse, breaking blood stasis, and its functions cannot be fully elaborated. It also treats throat bi with loss of voice, Yang-deficient bleeding, internally supporting carbuncles and sores, nine types of heart pain, hypochondriac pain, malaria, Ben Tun (rushing pig/qi), hernia qi, benefiting the lungs and suppressing liver, cold phlegm, cholera, wheezing, and distension.
Li Shizhen stated: Mahuang (Ephedra Herb) permeates the skin and hair, specializing in inducing sweating to disperse cold pathogens, because the Lung governs skin and hair, and pungent flavors enter the Lung. Guizhi penetrates Ying and Wei levels, thus resolving the muscle layer to eliminate wind pathogens, because the Spleen governs Ying, the Lung governs Wei, sweet flavors enter the Spleen, and pungent flavors enter the Lung. Rougui descends and benefits the source of fire. This is what Li Dongyuan referred to as "The Kidney dislikes dryness; urgently eat pungent substances to moisten it," opening the couli, producing essence fluids, and unblocking Qi.
Another record from *Yi Yu Lu* states: Someone suffered from red, swollen, and painful eyes, spleen deficiency preventing eating, and an increasingly strong Liver pulse. By doubling the amount of Rougui in mild and neutral herbs, it suppressed the Liver and benefited the Spleen, achieving two goals with one treatment. The Classic says "Wood withers with Cinnamon," referring to this. Therefore, Rougui can also treat cold, heat, deficiency, excess, interior, exterior, upper, and lower conditions. As long as the combination is appropriate, it yields immediate results.
I privately consider that Guizhi and Fuzi are generals who break through gates and seize doors; only skilled masters dare to use them lightly. However, Xue Lizhai frequently used these to treat insufficient True Fire and false heat from deficient Yang, achieving remarkable effects repeatedly, which ordinary physicians cannot match. Generally, Xue Lizhai's treatment method focuses on returning to the Mingmen; Li Dongyuan focuses exclusively on the Spleen and Stomach; Liu Wansu and Zhu Danxi focus exclusively on Ministerial Fire and Damp-Heat; Zhang Zihe focuses exclusively on attacking pathogens; Jiezhai Yinjun focuses exclusively on attacking phlegm and draining fire; Zhang Zhongjing focuses exclusively on external contraction. Treatment methods have their specialties; physicians must understand them comprehensively. To treat Mingmen disorders, use Xue Lizhai's method; to treat Spleen/Stomach disorders, use Li Dongyuan's method; to clear damp-heat, use Liu and Zhu's methods; to practice attack, use Zhang Zihe's method; to eliminate solid phlegm, use the Two Wangs' methods. Regarding Cold Damage, although following Changsha (Zhang Zhongjing), the treatment of the Three Yin meridians often uses Renshen, Baizhu, Danggui, and Fuzi, mostly to rescue the interior, thus not being exclusively focused on external contraction. If one utilizes the strengths of various schools without being limited by them, keeping the initiative oneself and adapting laws to the patient, utilizing the skills of many while drawing knowledge from one, this is the ideal state. Mr. Xue Lizhai, moreover, synthesized the greatness of all schools, revealed what predecessors had not, and enlightened future generations.
Alas, contemporary physicians view Guizhi and Fuzi as snakes and scorpions, failing to use them when indicated, ultimately leading to fatal errors. This is partly because Zhu Danxi claimed no one highlighted the dangers of Fuzi, causing people to stick to established theories and miss opportunities. Nevertheless, if used inappropriately, even Renshen can cause harm; why single out Guizhi and Fuzi? *Yi Xue Gang Mu* states: Huangqi (Astragalus Root) assists the fire of the Triple Burner; Renshen tonifies the Yang of all meridians; Baizhu (Atractylodes Rhizome) grows the Qi of the five Zang organs. These three are superior herbs; it depends on human comprehension to avoid misusing their Qi properties. I therefore add: Guizhi and Fuzi can rescue the collapse of Yin and Yang.